Top B2B Startups in North America

6sense is a B2B predictive intelligence engine for marketing and sales. Using its private network of billions of time-sensitive intent interactions, 6sense uncovers net-new prospects at every stage of the funnel and determines which existing prospects are in market to buy. 6sense predicts what products prospects will buy, how much they will buy, and when. 6sense is backed by Bain Capital Ventures, Battery Ventures, Venrock, and Salesforce and is based in San Francisco. 6sense.com

Modern Treasury builds payment operations software for high-growth companies. Our API and app modernize payment operations for disruptive companies building products that move and track money—think: rideshare marketplaces, digital wallet, fiat-crypto onramps—providing tools that help them grow faster. Enabling real-time payments, automatic reconciliation, continuous accounting, and compliance solutions, Modern Treasury’s platform is used to reconcile over three billion dollars per month. Founded in 2018, San Francisco-based Modern Treasury is backed by Benchmark, Altimeter, SVB Capital, Salesforce Ventures, NewView Capital, and Y Combinator.

Podium exists to help local businesses win. Using Podium’s technology, local businesses are able to simplify the way they build their business and modernize the way they communicate with their customers – from collecting payments, facilitating online reviews, launching marketing campaigns, and much more. Our work and focus on local business and helping them to build thriving businesses has been recognized across the industry, including Forbes’ Next Billion Dollar Startups, Forbes’ Cloud 100, the Inc. 5000 (#13), and Fast Company’s World’s Most Innovative Companies. For more about our product, watch this video. Podium has a positive, inclusive, and supportive culture and was recently named one of Inc. Magazine’s Best Workplaces for 2021 (4 years in a row). We look for people who are curious, creative and are willing to do the work to be a little better every day. We also embody our company values in all that we do, which always starts with being Customer Obsessed, followed by Be a Founder, Zero Drama, and Enjoy the Ride.

Field sales powers the economy — but most teams are struggling. Reps are buried in admin work, managers are stretched thin, and leaders can’t see what’s really happening in the field. Siro is redefining how field sales teams learn, perform, and win. We started as an AI-powered coaching platform that helped reps improve their outcomes in the field. Today, we’re something much bigger — an intelligent companion that automates sales reps’ tedious admin work, gives managers real-time visibility, and helps executives see around corners. Our platform integrates with systems like Salesforce, analyzing thousands of in-person sales conversations to surface insights, automate workflows, and drive better outcomes across the org. Think Iron Man’s Jarvis for sales — proactive, personalized, and built directly into the tools teams already use. Siro has raised $75M and is backed by world-class investors like Index, Fika, CRV, and SignalFire. We are trusted by leading home-improvement, retail, hospitality, and automotive brands, and powered by a lean team from Meta, McKinsey, Doordash, and Uber. We’re building the future of human-AI collaboration in sales — and we’re just getting started. ✔️ World-class team (McKinsey, Meta, DoorDash, Amazon) ✔️ Ambitious, high-ownership, collaborative culture built on relational responsibility ✔️ $75M raised from world-class investors (SignalFire, 01Advisors, CRV, Index Ventures, Fika Ventures) ✔️ 3x ARR YoY ✔️ Real traction with over 10,000,000 sales conversations recorded

Topsort is the leading AI and Auction-based retail media global company, transforming retailers and marketplaces into top ad networks on par with industry giants. Through seamless integration, Topsort provides a comprehensive Bidless™ retail media tech stack featuring highly flexible API tools, an industry-leading privacy-safe clean room with robust online and in-store attribution, and a transparent ad network for streamlined media buying across multiple ad networks. In just three years since launch, Topsort has raised $38 million in funding from investors like Pear Ventures, Quiet Capital, FJ Labs, and Upload Ventures.

At Paystand, we’re not just another fintech company—we’re trailblazers in decentralized finance (DeFi), transforming how businesses manage their finances. With thriving hubs in Santa Cruz, San Francisco, Austin, Minneapolis, Mexico City, Hermosillo, and Guadalajara, we’re leading a global revolution in financial systems. Recognized on the Inc. 5000 list for five consecutive years, we’re among the fastest-growing companies reshaping the future of finance. Our Expanding Ecosystem: Paystand isn’t just a company—it’s a growing global network. With the strategic acquisitions of Teampay, a leader in spend management, and Yaydoo, a top AR and AP platform in Latin America, we’re building an expansive ecosystem designed to revolutionize financial operations and fuel business growth worldwide.

One platform. One API. All Channels - from Pure-Play Webstore to Omnichannel infrastructure.

Modern Health is a mental health benefits platform for employers. They are the only solution to cover the full spectrum of mental well-being needs through both evidence-based technology and professional support from a certified coach or therapist. Whether someone wants to proactively manage stress or treat depression, Modern Health guides people to the right care at the right time and helps companies save money in engagement and healthcare costs. Modern Health has raised over $11M from Kleiner Perkins and Y Combinator and works with top companies that want to take a proactive approach to mental well-being.

Check is a payroll-as-a-service API that lets you embed payroll directly in your vertical SaaS, HR, or time-tracking platform. Our API abstracts away the complexities of running payroll: tax calculation, remittance, and filing, plus the movement of money between companies and employees. This enables companies to easily build fully integrated payroll products to offer to their customers. Check believes in a future where small business owners don’t have to think about payroll — it’ll simply be embedded in the platforms they already use to run their businesses. With the strong tailwinds of (1) the rise of vertical software and (2) the growth of embedded fin-tech at our back, Check is building the infrastructure to power that future, and ultimately we believe we’ll enable thousands of new platforms, millions of businesses, and hundreds of millions of workers.

Founded with a mission to revolutionize commercial real estate through innovation, VTS is the industry's leading leasing and asset management platform. By centralizing all of their critical data and workflows in one place, VTS empowers landlords and brokers to better attract, convert and retain their most valuable asset – tenants. Over 7 billion square feet is managed on the VTS platform by a user base exceeding 28,000. The firm's client roster comprises global commercial real estate leaders including Boston Properties, Beacon Capital Partners, Equity Office, LaSalle Investment Management, Hines, JLL and CBRE.