Top Enterprises Startups in 2026

Lyra is transforming mental health care through technology with a human touch to help people feel emotionally healthy at work and at home. We work with industry leaders, such as Morgan Stanley, Uber, Amgen, and other Fortune 500 companies, to improve access to effective, high-quality mental health care for their employees and their families. With our innovative digital care platform and global provider network, 10 million people can receive the best care and feel better, faster. Founded by David Ebersman, former CFO of Facebook and Genentech, Lyra has raised more than $900 million. Our roles can be full-time in our Burlingame, CA headquarters, OR virtual (remote candidates must be based in the United States).

H1 was built by scientists for scientists. We empower stakeholders at healthcare and life science companies to make smarter scientific decisions by providing access to critical data through an intuitive interface. Working with some of the largest and most influential global life science organizations, H1 provides insight into thought leaders, scholarly content, academics, and healthcare professionals with much more on the way.

Observe.AI, a leader in Contact Center AI, transforms customer experiences and improves agent performance by helping top brands analyze 100% of interactions, extract actionable sentiment and interaction insights, and streamline workflows. With Observe.AI, businesses transcribe every interaction with high accuracy and coach agents while gaining full visibility into their customer service operations. Observe.AI brings the power of agent assistance, automatic speech recognition, and Natural Language Processing (NLP) to modern contact centers and their frontline teams. Observe.AI is trusted by more than 160 customers and partners, including National Debt Relief, Root Insurance, Alcon Laboratories, and Pearson. Backed by Menlo Ventures, Next47, NGP Capital, Emergent Ventures, Scale Ventures, Nexus Ventures, and Y-Combinator, Observe.AI’s headquarters is in San Francisco with an office in Bangalore, India. For more information, visit observe.ai.

Security is hard. Breaches are happening daily. We watch over the networks of small and medium size businesses. We don't bother them with noise, we give them clear actions to take to make their network safe and clean.  A small appliance is dropped into the customer network. It gathers network information that we analyze with a combination of automated tools and a team of security experts. The customer gets human created instructions on addressing the issues or changing the network. 

Tipalti provides a holistic, multi-entity accounts payable solution. Organizations that employ Tipalti typically reduce 80% of their supplier payments workflow and are able to move towards a cost-neutral payables operation. Tipalti runs on a secure, cloud-based platform that includes a brandable supplier portal to enhances self-service, a true OCR-driven touchless invoice processing automation workflow with two-way and three-way PO matching, a KPMG-certified tax compliance module, global payment remittance to over 190 countries and 120 currencies across six payment methods, a friction-less early payments capability that streamlines negotiation and adoption, and bi-directional, real-time payment reconciliation. Tipalti is trusted by Amazon, GoDaddy, Roku, Twitter, and hundreds of other innovative companies looking to transform payables so their finance teams can focus on more strategic efforts and company growth.

Immuta is the unified data platform for the world’s most secure organizations. Our technology frees data science teams to securely access and work with high-value data. The Immuta platform streamlines data management workflows to solve for the organizational challenges facing modern data science operations. Our customers trust our platform for its precise controls. They depend on it to create secure virtual data collaboration environments on-demand. Immuta was founded in 2014 and is headquartered in College Park, Maryland. Platform customers include global financial institutions, telecommunications companies and national security organizations.

Pilot specializes in bookkeeping and tax prep for high-growth technology startups, ranging from pre-seed to Series C. (We're built by startup founders for startup founders. This is the third startup for this founding team and we've felt this pain before, so we know what it's like.) When you work with Pilot, you’re paired with a dedicated finance expert who takes the work off your plate (and is available to answer your questions)—so you can focus on your business.

Continuous Delivery. Simplified. Simplify Even Complex Deployments. Implement pipelines with complex delivery strategies like blue/green, canary, or rolling upgrades in a matter of minutes, and without having to maintain ginormous amounts of scripts. Protect Yourself from Failure with Machine Learning. Automatically verify the success of deployments, including performance, quality, and functionality. Automatically roll back deployments when things don’t look right. Harness’s unique machine learning gives you a safety net at all times. Practice DevOps without Sacrificing Security. Harness has everything you need—integrated secrets management, role-based access control, audit trails, and compliance reports that will keep your SecOps teams nice and happy.

Sysdig is the secure DevOps company, and we’re at the forefront of the container and Kubernetes revolution. We are passionate, technical problem-solvers, continually innovating and delivering powerful solutions to secure and operate cloud-native applications in production. Our consistent contributions to open source software projects reflect our commitment to the open cloud movement. We value diversity and open dialog to spur ideas, working closely together to achieve goals. And we're a great place to work too — we were awarded the 2019 Bay Area Best Places to Work Award from San Francisco Business Times and the Silicon Valley Business Journal. We are looking for team members who share our commitment to customers and are willing to dig deeper, understand problems and deliver innovative solutions.

As the pioneer in Continuous Product Design, Quantum Metric helps organizations put customers at the heart of everything they do. The Quantum Metric platform empowers a customer-centric culture, helping business and technology teams align faster on customer needs and prioritize the opportunities that will drive the most value. Today, Quantum Metric captures insights from 29 percent of the world’s internet users, supporting globally recognized brands in retail, travel, financial services, and telecommunications. In January of 2021, Quantum Metric secured its place as a tech unicorn with an above $1 billion valuation and a $200 million Series B funding round. For more information about Quantum Metric, visit quantummetric.com