Top Tech Startups in United States in 2027

TrialSpark is transforming the way new medical treatments are brought to market. We’re a technology company that runs end-to-end clinical trials through a network of our own TrialSpark-operated trial sites, making the entire lifecycle of clinical trials more efficient, accessible, and patient-centric. We're growing quickly and would love to have you join us!

NextRoll is a leading marketing technology company that empowers businesses to drive sustainable growth while building trusted connections with their audiences. Built on nearly two decades of AI and data expertise, NextRoll delivers its solutions through AdRoll, its flagship brand and connected advertising platform. The AdRoll platform brings together two powerful offerings: the AdRoll product, which helps brands generate awareness, deepen engagement, and drive measurable revenue through AI-powered multi-channel campaigns; and AdRoll ABM, a full-funnel account-based marketing product that unifies buyer insights, predictive AI, and multi-touch advertising to accelerate pipeline and revenue for B2B teams. Together, these solutions give marketers the clarity, efficiency, and performance they need to grow with confidence. NextRoll is a privately held company headquartered in San Francisco, CA.

AssemblyAI is a remote-first company building powerful AI models for developers, startups, and enterprises to transcribe and understand their audio data. Our mission is to make production-ready, state-of-the-art AI models accessible to developers and product teams at extremely large scale through simple APIs. Customers, including Spotify, Algolia, Dow Jones, Happy Scribe, BBC, The Wall Street Journal, and NBCUniversal, use our APIs to transcribe and understand millions of videos, podcasts, phone calls, and zoom meetings every day. Our APIs power innovative products like conversational intelligence platforms, meeting summarizers, content moderation, and automatic closed captioning. We're growing at breakneck speed, and recently announced our Series B round. We've raised $63M in total funding, backed by leading investors including Insight Partners, Accel, Y Combinator, Patrick and John Collision (Founders of Stripe), Nat Friedman (Former CEO of GitHub), and Daniel Gross (Entrepreneur & Investor in companies including GitHub, Uber & SpaceX). Our team is made up of problem solvers, innovators, and top AI researchers from companies like DeepMind, Google Brain, Meta AI, Amazon and Apple. They conduct cutting-edge AI research and develop novel algorithms and techniques to continually push the state-of-the-art in speech recognition and NLP. Join our world-class, remote team and help us build an iconic deep learning company!

Humaans is the fastest way to onboard and manage your staff. It turns complex processes like employee onboarding, offboarding, and compensation management into simple workflows by integrating with other point solutions, such as Gsuite, Slack, Docusign, and Greenhouse. We're building a new kind of employee management system designed to help People Ops, Finance, and IT teams operate collaboratively by using the best in class point solutions they want for their staff while maintaining a central record of employee data. How do we get there? By focusing relentlessly around customers’ needs and their experience, and prioritising design, quality and performance.

Today Sudowrite is an AI assistant used by novelists, screenwriters, essayists, and more. It helps writers get unstuck and suggests language, character backstories, and plot points, all while following the tone and narrative arc of the manuscript. Tomorrow, Sudowrite will be the writer's most-trusted collaborator, always available to brainstorm and co-write their best possible story. In ten years, we imagine a suite of AI-powered tools to augment and accelerate human creativity. We believe all creative work will eventually be a collaboration between human and AI. That said, Sudowrite will be our focus for quite some time.

Caribou is a fast-growing, mission-driven fintech that delivers financial security and peace of mind to consumers by providing better auto refinancing, insurance and financial protection products. Through our partnerships with top local and community lenders, we bring customers great rates and lower monthly payments. Our secure, digital platform makes it easy for our customers to see exactly how much they can save and complete the refinance process quickly, all from the comfort of their home. What's more, we do all the heavy lifting, including paying off the old lender as well as re-titling the vehicle, saving our customers those dreaded trips to the DMV.

TapTab is a TikTok-style interface from which diners can place orders and make reservations directly from videos.

Field sales powers the economy — but most teams are struggling. Reps are buried in admin work, managers are stretched thin, and leaders can’t see what’s really happening in the field. Siro is redefining how field sales teams learn, perform, and win. We started as an AI-powered coaching platform that helped reps improve their outcomes in the field. Today, we’re something much bigger — an intelligent companion that automates sales reps’ tedious admin work, gives managers real-time visibility, and helps executives see around corners. Our platform integrates with systems like Salesforce, analyzing thousands of in-person sales conversations to surface insights, automate workflows, and drive better outcomes across the org. Think Iron Man’s Jarvis for sales — proactive, personalized, and built directly into the tools teams already use. Siro has raised $75M and is backed by world-class investors like Index, Fika, CRV, and SignalFire. We are trusted by leading home-improvement, retail, hospitality, and automotive brands, and powered by a lean team from Meta, McKinsey, Doordash, and Uber. We’re building the future of human-AI collaboration in sales — and we’re just getting started. ✔️ World-class team (McKinsey, Meta, DoorDash, Amazon) ✔️ Ambitious, high-ownership, collaborative culture built on relational responsibility ✔️ $75M raised from world-class investors (SignalFire, 01Advisors, CRV, Index Ventures, Fika Ventures) ✔️ 3x ARR YoY ✔️ Real traction with over 10,000,000 sales conversations recorded

Recent Awards / Mentions: - Apple's Top 10 Apps in the World - Business Insider's most innovative companies in the world along with Uber and Snapchat: At Lark, we’re on a mission to improve people’s health and happiness through our digital health coach AI which has become the first A.I. nurse to be reimbursed as a live healthcare professional. Our app takes data from phones and wearables, and uses it to create a personalized health "chat bot" buddy that sticks with users and helps them stay active, sleep more, and eat healthy. We are using NLP to process millions of meals, and accelerometer data to compute activity and sleep amounts from users' phones. Our chat AI is the most sophisticated digital health engagement tool in the world. Join us and make it even better!

OfferUp is changing how people buy and sell locally by making it as easy as taking and sharing a photo from your phone. We are not just about connecting buyers and sellers; we are about creating a simple and safe marketplace that changes people’s lives. OfferUp is a top 10 shopping app on Google Play and a top 20 app in the Lifestyle category on iTunes.