Top Non Profit Startups in 2026

At ActBlue, we build and power the premier online fundraising platform for Democratic campaigns, progressive organizations, and nonprofits working to create a better future. We put power in the hands of small-dollar donors and make giving online as easy as possible. And we work with thousands of groups -- from presidential candidates to environmental organizations to local school board members.

Talkdesk is the world's leading browser-based call center software. Our out-of-the-box call center software solution helps growing businesses improve customer satisfaction, while simultaneously reducing support costs. Using Talkdesk, businesses can create an entire call center in the browser in 5 minutes. No phones, hardware, coding or downloads required - all that is needed is a computer and Internet. With one click, Talkdesk integrates with Salesforce, Zendesk, Shopify, Olark and others to provide comprehensive information about customers. Using IVR, ACD and skills-based routing, callers are routed to the agent who is most qualified to meet their needs based on customizable data. Talkdesk then displays the caller's name, image, contact information, purchase history and contact history in the agent's browser in real-time. With real-time and historical reporting, call monitoring and call recording, teams can make data-driven decisions based on comprehensive information.

We started Box in 2005 to make it easy to access information from anywhere and collaborate with anyone. While that vision still lies at the core of our business, it has transformed into our mission to power how the world works together. Today, we're proud to call 97,000 companies and 68% of the Fortune 500 our customers — but we're just getting started. As work continues to evolve, we stay focused on delivering innovation to organizations across the globe and blowing our customers' minds every day.

charity: water is reinventing charity - 100% model that uses every cent of public money to directly fund water projects - Proving every dollar with online reports with GPS coordinates and photos - Working with local implementing partners, ensuring longterm sustainability in all of our solutions Currently, about 130 private donors fund our staff and operating costs through a private giving program called The Well. That means 2M+ public donors have been able to help us serve over 10M people clean water since 2006.

CharterUP aims to be the leading charter bus platform in the world and is looking for people that want to be along for the ride! We are disrupting the highly fragmented bus industry by connecting supply-side bus companies to demand-side clients (corporations, non-profits, and governmental entities). We strive towards having as many enthusiastic customers as possible, which leads to increased group travel and a greener earth.

For nearly 100 years, the ACLU has been our nation’s guardian of liberty, working in courts, legislatures, and communities to defend and preserve the individual rights and liberties guaranteed by the Constitution and laws of the United States. Whether it’s ending mass incarceration, achieving full equality for the LGBT community, establishing new privacy protections for our digital age, or preserving the right to vote or the right to have an abortion, the ACLU takes up the toughest civil liberties cases and issues to defend all people from government abuse and overreach. With more than a million members, activists, and supporters, the ACLU is a nationwide organization that fights tirelessly in all 50 states, Puerto Rico, and Washington, D.C., for the principle that every individual’s rights must be protected equally under the law, regardless of race, religion, gender, sexual orientation, gender identity or expression, age, disability, national origin, record of arrest or conviction.

In partnership with the New York City Mayor’s Office of Criminal Justice, the Criminal Justice Agency, (CJA) is New York City’s main pretrial services agency, combining operations, demonstration projects, and research under one roof. CJA provides pretrial services to the courts and about 250,000 persons arrested annually in New York City.

Moonshot edVentures envisions a learner-centered system, led by individuals who share and empathize with the experience of the students and communities they aim to serve, where all children become life-long learners who persist through life and meaningfully contribute to their communities.

mHUB is creating the conditions for product innovation to thrive. Our mission is to galvanize Chicago's manufacturing ecosystem by providing access to labs and equipment, attracting world-class talent, and fostering collaboration between industry and entrepreneurs to solve challenges and spark new ideas. mHUB helps turn ideas into prototypes, and prototypes into sustainable new businesses that drive economic impact, and ensure the region's continued leadership in global manufacturing. mHUB Accelerated Incubation is a six-month, hands-on startup accelerator focused on the product development and commercialization of early-stage, high-potential hardtech startups. mHUB will focus on startups building and growing demand-driven technologies in industries such as Industrial Internet of Things (IIoT), medical devices, connected buildings and home, communication technologies, smart cities, smart mobility and energy technology. Applications for the MedTech cohort will open in summer 2021 with the program commencing in Chicago in Q4. MedTech is the second vertical accelerator cohort of six that will launch over the next three and a half years and be supported by mHUB’s Product Impact Fund. More information on the accelerator and the Product Impact Fund can be found at mhubaccelerator.com. mHUB’s Product Impact Fund I Is a $15M venture fund that invests in seed and early-stage physical product and hardware companies with deployment from 2020 To 2023. The fund will invest in 60 high-performance startups that participate in six sector-specific cohorts of mHUB’s Accelerated Incubation program. The Fund will invest $75,000 cash and $56,750 in product development, resources and programming during a six-month highly structured incubation (with two full years of support) in exchange for 5% equity with pro rata rights. 30% of the fund will be reserved for follow- on capital to exercise pro rata rights for a select set of portfolio companies’ Series A rounds.

Code for America is committed to building a team as diverse as the nation we serve. We’re made up of people-centered problem solvers: technologists, advocates, storytellers, and organizers from many different backgrounds and communities around the country. We merge the best parts of technology, nonprofit, and government. We believe government at all levels can and should work well for everyone— and the mindful use of technology makes it possible. We’re known for building digital tools, but the work doesn’t stop there. We seek to transform government by showing what’s possible when communities are included in policy and service design. We use insights and ideas from real people to guide us to real solutions that break down barriers to meet community needs and improve government in meaningful ways. Want to use your skills for good and help us drive change that lasts? Join our team!