Top Tech Startups in South America in 2026

We're building the data platform to power safe and fair decisions. Checkr provides fast, accurate information to power informed decisions. Our innovative technology and robust data platform help customers assess risk and ensure safety and compliance to build trusted workplaces and communities. We’re a team that thrives on solving complex problems with innovative solutions that advance our mission. Come join us!

Through the development of a first of its kind open platform, Platform Science provides the hardware and software that allows clients to fully capture, analyze and apply a wealth of data, dramatically increasing performance, compliance, time management and savings.

AssemblyAI is a remote-first company building powerful AI models for developers, startups, and enterprises to transcribe and understand their audio data. Our mission is to make production-ready, state-of-the-art AI models accessible to developers and product teams at extremely large scale through simple APIs. Customers, including Spotify, Algolia, Dow Jones, Happy Scribe, BBC, The Wall Street Journal, and NBCUniversal, use our APIs to transcribe and understand millions of videos, podcasts, phone calls, and zoom meetings every day. Our APIs power innovative products like conversational intelligence platforms, meeting summarizers, content moderation, and automatic closed captioning. We're growing at breakneck speed, and recently announced our Series B round. We've raised $63M in total funding, backed by leading investors including Insight Partners, Accel, Y Combinator, Patrick and John Collision (Founders of Stripe), Nat Friedman (Former CEO of GitHub), and Daniel Gross (Entrepreneur & Investor in companies including GitHub, Uber & SpaceX). Our team is made up of problem solvers, innovators, and top AI researchers from companies like DeepMind, Google Brain, Meta AI, Amazon and Apple. They conduct cutting-edge AI research and develop novel algorithms and techniques to continually push the state-of-the-art in speech recognition and NLP. Join our world-class, remote team and help us build an iconic deep learning company!

Domino powers model-driven business for the world’s most advanced enterprises, including over 20% of the Fortune 100. Our Enterprise MLOps platform speeds up the development and deployment of data science work while increasing collaboration and governance, to scale data science into a competitive advantage. Our platform enables thousands of data scientists to develop better medicines, grow more productive crops, adapt risk models to major economic shifts, build better cars, improve customer support, or simply recommend the best purchase to make at the right time. Domino is backed by leading venture capital firms: Sequoia Capital, Bloomberg Beta, Coatue Management, Dell Technologies Capital, Highland Capital Partners, In-Q-Tel, and Zetta Venture Partners.

Brex is building a first-of-its-kind solution to integrate the financial services and software that businesses need to be successful. While they build the future, we’ll be building everything they need to launch confidently and scale smarter. We are a hybrid company, optimizing for flexibility and connection. Our employees work remotely while coming to the office for a few coordinated days per week. We have offices in San Francisco, New York, Seattle, Salt Lake, Vancouver BC and Sao Paulo.

MongoDB is the leading modern, general purpose database platform, designed to unleash the power of software and data for developers and the applications they build. Headquartered in New York, MongoDB has more than 15,000 customers over 100 countries. The MongoDB database platform has been downloaded over 60 million times and there have been more than one million MongoDB University registrations.

Altinity is the leading service and software provider for ClickHouse - an open source SQL data warehouse offering industry-leading query speeds on petabyte-scale data. Altinity offers the highest expertise on the market to help customers deploy and run the most demanding analytic applications. We also provide innovative software to manage ClickHouse in Kubernetes, cloud, and bare metal environments.

LILT is a language translation services and technology company. We're building the next generation of localization, making it possible for every organization to communicate with their customers in the language of their choice through LILT's high-quality, scalable, and affordable translation services. We recruit the world's best human translators and equip them with our software, allowing them to translate better and faster than ever. By combining human expertise and machine efficiency in a complete enterprise localization solution, we can deliver technology-enabled translation services to our customers. Lilt is backed by some of the world's leading investors including Sequoia Capital, Intel Capital, and Redpoint. Our customers include some of the largest Fortune 500 companies in the world who rely on Lilt every day to provide more personal customer experiences in 300+ languages. Our team is headquartered in the Bay Area with additional hubs in Indianapolis, Washington DC, Berlin, Dublin, and the UK.

Topsort is the leading AI and Auction-based retail media global company, transforming retailers and marketplaces into top ad networks on par with industry giants. Through seamless integration, Topsort provides a comprehensive Bidless™ retail media tech stack featuring highly flexible API tools, an industry-leading privacy-safe clean room with robust online and in-store attribution, and a transparent ad network for streamlined media buying across multiple ad networks. In just three years since launch, Topsort has raised $38 million in funding from investors like Pear Ventures, Quiet Capital, FJ Labs, and Upload Ventures.