Top Tech Startups in United States in 2026

Pico MES is a team of engineers and designers with a strong background in manufacturing, web development, hardware, and UX/UI design. We produce a web-based product which allows manufacturing engineers and technicians to create and manage their entire workflows within the factory. We also provide a distributed hardware system for integrating the hundreds if not thousands of devices on the factory floor. Ultimately our goal is simple: we like to build stuff - and we want to help others build their products with a tool that meets their needs. We're a team of technical experts and humble learners that understand what it takes to build a highly capable manufacturing line. And now we need your help as we evolve and improve each and every day.

Volta Labs was spun out of MIT in 2018 with the simple mission of building biological automation from the ground up. Volta is in the proximity of Kendall Square, known as "the most innovative square mile on the planet". Being part of the open biotech culture in Kendall Square made us realize that today’s biologists are held back by the limitations of existing automation tools. With DNA sequencing in particular, we observed that the advances in DNA readout technologies had moved further along than the advances in the upstream steps of preparing samples for sequencing (sample prep). ‍ What started out as a simple printed circuit board to manipulate colored droplets at the MIT Media Lab during co-founder Udayan Umapathi’s graduate work was quickly directed toward solving the “sample prep bottleneck”. The company raised Seed Funding from top VCs in 2019 and later that year added Will Langford as a co-founder and Head of Engineering. ‍ Since then, we have been heads down in the lab inventing and building novel fluidic and sample manipulation technologies. We take an anti-disciplinary approach to solve very hard problems and weave together instrumentation, fluidics, software, biology and chemistry. While our current focus is on sequencing sample prep, we envision a new approach where a single universal machine automates most biological workflows in genomics, proteomics and synthetic biology.

At Willow Innovations, Inc., our vision is to create a better world for moms. We are focused on identifying where moms need support in the motherhood journey, and building hardware- and software-based solutions around their needs. In 2014, we created the first-ever cord-free Willow™ Wearable Breast Pump, revolutionizing the industry. Fast forward to today, we are building a portfolio of physical and digital products to solve mom's most meaningful problems and improve their lives. Willow Innovations, Inc. sits at the unique and exciting intersection of HealthTech, FemTech, Consumer Goods, and Med device. Our potential for scale and impact is extraordinary—we’re just getting started. We’re looking for talented, passionate team players to help us deliver our mission and vision. If this sounds like you, we'd love to hear from you! Recent awards we’ve won include: - Great Place to Work Certified 2021–2022 - Omnis Awards, Outstanding Culture and Communication

Contra is a professional community for your independent journey. Digital professionals use Contra to create stunning visual profiles, earn money commission-free, and build high-quality professional communities and referral networks. Contra was started by a group of independents who were tired of existing professional networks that are blind to the needs of digital professionals. We’re creating a new way to work for the independent digital workforce.

Astra is a next-generation financial services company focused on providing advanced payment technology for financial institutions, fintech startups, and enterprises. The company’s full-stack payments platform enables its customers to offer real-time, programmatic transfers between their users’ accounts.

Construction is an industry built on change. With each new project, we change skylines, strengthen communities, and transform cities for the better.‍ But the reality isn’t always so simple. Between compliance and change orders, false starts and permit delays, the construction industry has a paperwork problem—especially when it comes to getting paid.‍ Cash flow is the lifeline of any contractor’s business, but billing is painful and slow. With so much manual work involved, a small, honest mistake can hold up millions of dollars in cash flow. And even when things go right, the time and effort it takes to get paid takes away from the work that really matters. We believe that when you free up payments, you free up people to take on whatever’s next. We started Siteline to give construction teams a financial foundation to build on. Because when people are on the same page about getting paid, they can focus on whatever's next—whether that’s a new idea, a new project, or more time with their family. We’re reimagining construction finance to help contractors get paid, grow their business, and build a better future for all of us.

Ascend is revolutionizing the financial operations of the insurance industry. Insurance accounts for a staggering 7.2% of global GDP but more than 40% of payments still reliant on paper checks. We automate the financial tasks associated with selling and buying insurance from end-to-end — from online customer payments, premium financing, to the distribution of commissions and carrier payables. We help digital distributors sell more insurance by simplifying operations, reducing payment friction and delivering the modern checkout experience customers expect. 

Headquartered in New York City, Take-Two Interactive Software is a leading developer, publisher and marketer of interactive entertainment for consumers around the globe. Our company develops and publishes products principally through its wholly-owned labels Rockstar Games and 2K, as well as its Private Division label and Social Point, a leading developer of mobile games. Some of our largest hits include the Civilization series, NBA2K, Bioshock Infinite as well as many other titles throughout the years.

We are a "one-stop" sales and marketing agency servicing every phase of the sales and marketing cycle. Our services include lead generation, marketing, sales, customer service, prospect list building, and CRM consulting.

Volley builds the best voice-controlled games and entertainment experiences for Amazon Alexa, Google Assistant, smartphones, and Fire TVs. Popular Volley voice games include Song Quiz, Jeopardy!, and The Price Is Right. Our voice apps are used by millions of people every month. We believe voice control will become the main way people access entertainment in their bedrooms, kitchens, living rooms, and cars, and our goal is to become the "Netflix of Voice" for this emerging category of devices. Volley was founded by Max Child and James Wilsterman in 2016. We're a 60+ person hybrid remote/in-person company, headquartered in the Hayes Valley neighborhood of San Francisco. While we work to make home entertainment more accessible and engaging, we like to have fun along the way, with team lunches, Friday happy hours, and very active #food and #pets slack channels. If any of this sounds fun to you (we promise it is), come join us! Read more about Volley's culture and mission here: volleythat.com/post/volley-mission-culture-and-what-we-create