Top Medical Devices Startups in 2026

THE PROMISE With ultrasound a doctor can see into the heart of someone in cardiac arrest or into the abdomen of a woman with an ectopic pregnancy, and save their lives. 75 years after its invention, ultrasound remains an indispensable tool for diagnosis and monitoring. THE PROBLEM 60% of the world lacks access to medical imaging because current technologies are unwieldy, expensive, and require extensive training. While doctors carry supercomputers in their pockets, they still rely on the 200-year old stethoscope​ as their primary diagnostic tool. THE SOLUTION Our mission is to democratize healthcare by making medical imaging accessible to everyone around the world. Butterfly Network has raised >$350M to develop and commercialize a handheld, smartphone-connected ultrasound probe powered by AI. We operate at the intersection of medicine, engineering, and machine learning to create breakthrough technology that becomes smarter with each new patient.

As population continues to age, there is a growing demand for motor rehabilitation services. The problem is that the way we address this growth or rehabilitation services (physical therapy) has not changed in thirty years because we are still heavily reliant on a one-to-one patient therapist interaction which is costly, non scalable, and difficult to ensure consistent quality. At SWORD Health, we saw the opportunity to take a truly disruptive and transformative approach to this problem by creating the first digital therapy solution that addresses the growing demand for therapy while reducing costs, empowering patients with their recovery to ultimately recover faster, and providing a rich source of data for clinical teams and decision makers. Video: vimeo.com/118489111

Kalogon is the trusted leader in seated health, delivering inventive seating solutions that eliminate the stresses of sitting. Driven by clinical research, deep customer empathy and rapid product iterations, Kalogon's solutions serve anyone who sits for extended periods, across healthcare, aviation and beyond. Kalogon’s proprietary technology combines real-time sensors, adaptive surfaces and personalized control to restore circulation, protect skin integrity and reduce fatigue. Founded in 2019 and headquartered in Melbourne, Fla., Kalogon manufactures all products in-house. Our team is a blend of experienced tech industry veterans, passionate engineer, and people focused on ways to help folks stay seated and stay healthy.

At 4Catalyzer we strive to transform 21st century medicine by solving today’s most challenging problems – across life science research tools, medical devices and therapeutics. We aspire to create significant societal impact and are motivated by the idea that our products will change the lives of people we love. Fundamentally, we are focused on developing new types of sensors and pairing them with deep learning to get a window into biology and medicine that nobody has ever had before. We have audacious plans – but we have an unbeatable team and a founder that has disrupted biomedical science successfully more than once. If you have experience in image reconstruction, mixed-signal IC design, high-speed electronics, nanophotonics, microfabrication, MEMs, biophysics, biochemistry, molecular biology, deep learning, cloud computing, embedded systems, or hold any dual degree with distinction along with computer science please contact us and “put a dent in the universe”.

iSono Health is developing AI-powered solutions for accessible and personalized health monitoring . Our first solution, ATUSA, combines a wearable, automated ultrasound and AI to transform breast cancer screening by increasing quality, improving access, and lowering cost. ATUSA system produces repeatable 3D images, independent of operator skill in 1min, enabling accurate and rapid diagnosis. iSono Health’s deep learning technology extracts acoustic biomarkers from quantitative ultrasound data to identify and track functional properties of breast tissue enabling early detection and monitoring of breast cancer.

Element Science is currently focused on developing a device to protect vulnerable populations experiencing temporary periods of elevated risk for sudden cardiac death, successfully and cost-effectively while delivering an outstanding patient experience. By leveraging significant advances in technology and materials, it is creating a novel therapeutic wearable that will allow many more patients at risk of sudden cardiac death globally to receive a potentially life-saving therapy.

The biggest waste in manufacturing today is not on the shop floor. It's in the meetings, emails, and data transfer that overwhelm knowledge processes (eg quality assurance, vendor management, engineering, R&D, and sales). That's because traditional enterprise tools split collaboration and processes into disparate systems, resulting in up to 85% of time and effort being wasted. Unifize solves this problem by bringing collaboration and process into one place. By creating a conversation for every process record, Unifize measurably reduces waste in knowledge processes by up to 95%.

Eko is a digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its suite of AI-powered digital tools. Its FDA-cleared technology is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect disease earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko is headquartered in Oakland, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. Eko exists to ensure all patients have access to early heart and lung disease detection that improves and extends their lives.

Leucine is multiplying on its mission to make global drug manufacturing compliant and audit-ready. Within a short period, we have signed up Fortune 500 companies as customers and raised funds from marquee VC investors. Hundreds of pharmaceutical manufacturing & quality teams globally use the Leucine no-code platform daily to improve drug quality, efficiency, and sustainability by orchestrating 300+ complex regulated workflows from material receipt to batch release. We are now looking to onboard ambitious individuals across engineering, product, design, customer success, and sales to scale the product.

At Willow Innovations, Inc., our vision is to create a better world for moms. We are focused on identifying where moms need support in the motherhood journey, and building hardware- and software-based solutions around their needs. In 2014, we created the first-ever cord-free Willow™ Wearable Breast Pump, revolutionizing the industry. Fast forward to today, we are building a portfolio of physical and digital products to solve mom's most meaningful problems and improve their lives. Willow Innovations, Inc. sits at the unique and exciting intersection of HealthTech, FemTech, Consumer Goods, and Med device. Our potential for scale and impact is extraordinary—we’re just getting started. We’re looking for talented, passionate team players to help us deliver our mission and vision. If this sounds like you, we'd love to hear from you! Recent awards we’ve won include: - Great Place to Work Certified 2021–2022 - Omnis Awards, Outstanding Culture and Communication