Top Medical Devices Startups in 2027

More than a new kind of dialysis machine, Tablo is a new way of thinking about dialysis and the patients who depend on it. Tablo makes it possible to reconsider where dialysis is performed, when dialysis is performed and who can perform it. Tablo opens up opportunities for new in-center patient-powered care models designed to improve the experience while lowering costs for providers.

Kalogon is the trusted leader in seated health, delivering inventive seating solutions that eliminate the stresses of sitting. Driven by clinical research, deep customer empathy and rapid product iterations, Kalogon's solutions serve anyone who sits for extended periods, across healthcare, aviation and beyond. Kalogon’s proprietary technology combines real-time sensors, adaptive surfaces and personalized control to restore circulation, protect skin integrity and reduce fatigue. Founded in 2019 and headquartered in Melbourne, Fla., Kalogon manufactures all products in-house. Our team is a blend of experienced tech industry veterans, passionate engineer, and people focused on ways to help folks stay seated and stay healthy.

Eli is a women's health company on a mission to improve lifelong health through continuous hormone monitoring. Hormones impact physical and mental health every day and at every stage of life. Eli offers real-time insights from hormones in saliva that can be tracked continuously over time, unlike traditional testing methods or send-out tests that only provide a single snapshot. With just three simple steps, Eli's at-home technology provides women with personalized hormone profiles to make informed decisions about their health. Eli is filling a data gap to transform how women manage their hormonal health in key areas like menopause, fertility, contraception, and endocrine conditions. Eli has raised a total of $9 million so women can have the information they need to optimize their overall health from puberty to beyond menopause.

AcuityMD is bringing transparency and efficiency to the medical device market by helping suppliers build stronger and compliant relationships with doctors and other healthcare providers. Our vertical-focused SaaS and data platform helps Medical Device sales, marketing, medical education, and product development teams collaborate around the multi-faceted relationships these companies have with the users of their products.

iSono Health is developing AI-powered solutions for accessible and personalized health monitoring . Our first solution, ATUSA, combines a wearable, automated ultrasound and AI to transform breast cancer screening by increasing quality, improving access, and lowering cost. ATUSA system produces repeatable 3D images, independent of operator skill in 1min, enabling accurate and rapid diagnosis. iSono Health’s deep learning technology extracts acoustic biomarkers from quantitative ultrasound data to identify and track functional properties of breast tissue enabling early detection and monitoring of breast cancer.

Element Science is currently focused on developing a device to protect vulnerable populations experiencing temporary periods of elevated risk for sudden cardiac death, successfully and cost-effectively while delivering an outstanding patient experience. By leveraging significant advances in technology and materials, it is creating a novel therapeutic wearable that will allow many more patients at risk of sudden cardiac death globally to receive a potentially life-saving therapy.

Eko is a digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its suite of AI-powered digital tools. Its FDA-cleared technology is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect disease earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko is headquartered in Oakland, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. Eko exists to ensure all patients have access to early heart and lung disease detection that improves and extends their lives.

Leucine is multiplying on its mission to make global drug manufacturing compliant and audit-ready. Within a short period, we have signed up Fortune 500 companies as customers and raised funds from marquee VC investors. Hundreds of pharmaceutical manufacturing & quality teams globally use the Leucine no-code platform daily to improve drug quality, efficiency, and sustainability by orchestrating 300+ complex regulated workflows from material receipt to batch release. We are now looking to onboard ambitious individuals across engineering, product, design, customer success, and sales to scale the product.

At Willow Innovations, Inc., our vision is to create a better world for moms. We are focused on identifying where moms need support in the motherhood journey, and building hardware- and software-based solutions around their needs. In 2014, we created the first-ever cord-free Willow™ Wearable Breast Pump, revolutionizing the industry. Fast forward to today, we are building a portfolio of physical and digital products to solve mom's most meaningful problems and improve their lives. Willow Innovations, Inc. sits at the unique and exciting intersection of HealthTech, FemTech, Consumer Goods, and Med device. Our potential for scale and impact is extraordinary—we’re just getting started. We’re looking for talented, passionate team players to help us deliver our mission and vision. If this sounds like you, we'd love to hear from you! Recent awards we’ve won include: - Great Place to Work Certified 2021–2022 - Omnis Awards, Outstanding Culture and Communication

THE PROMISE With ultrasound a doctor can see into the heart of someone in cardiac arrest or into the abdomen of a woman with an ectopic pregnancy, and save their lives. 75 years after its invention, ultrasound remains an indispensable tool for diagnosis and monitoring. THE PROBLEM 60% of the world lacks access to medical imaging because current technologies are unwieldy, expensive, and require extensive training. While doctors carry supercomputers in their pockets, they still rely on the 200-year old stethoscope​ as their primary diagnostic tool. THE SOLUTION Our mission is to democratize healthcare by making medical imaging accessible to everyone around the world. Butterfly Network has raised >$350M to develop and commercialize a handheld, smartphone-connected ultrasound probe powered by AI. We operate at the intersection of medicine, engineering, and machine learning to create breakthrough technology that becomes smarter with each new patient.