Top Tech Startups in United States in 2027

PE backed start-up, DoseSpot is a dynamic and innovative leader in the electronic prescribing software market. We are on a hyper-growth curve at the intersection of the software and healthcare industries. DoseSpot provides ePrescription software enabling clinicians to write and transmit prescriptions to pharmacies electronically. Founded in 2009 and based in Dedham, MA, DoseSpot serves more than 300 healthcare clients, from digital/telehealth providers and hospice pharmacies to dental services organizations and EMR/EHR and practice management software companies. pVerify, a division of DoseSpot, is the leader in Real-time Healthcare APIs for Eligibility, Insurance Discovery, Instant Prior Authorization, Estimation, Claim Status, and DME Solutions. pVerify is a unique service-oriented healthcare company that focuses on value-added solutions for ambitious health and wellness providers. We shine in the industry for unparalleled hands-on support, excellent development tools, and a pre-and post-development foundation unrivaled as a service-oriented partner. pVerify was recently acquired by DoseSpot and will operate independently while working together to identify natural points of cross-collaboration and integration. This position will be on the pVerify Team.

iSpot.tv helps advertisers measure the brand and business impact of TV and streaming advertising, from concept to airing to conversion. Fast, accurate and actionable measurement and attribution solutions enable advertisers to assess creative effectiveness, enhance media plans and attribute advertising results for cross-platform campaigns, all while benchmarking against competitors and historical norms. Unlike legacy and ad hoc solutions, iSpot is purpose-built to measure the performance of every ad on television with digital-like precision and granularity in real time. With always-on performance insights unified across linear and streaming TV, advertisers can take quick and confident action to consistently drive business results.

Dentistry Automation builds revenue cycle automation software for dental practices and DSOs. Our platform helps clinics reduce administrative friction across insurance and billing workflows — from eligibility and claims to payment posting and reconciliation. By replacing manual, error-prone processes with automation and APIs, we help practices improve cash flow, lower operating costs, and scale revenue without proportional increases in staffing. We work with forward-thinking dental organizations that want modern infrastructure behind their financial operations — not more spreadsheets, portals, or back-office chaos.We build RCM products to help dental office to reduce friction, improve bottom line and collect faster

Matriosh is a US-based stealth-mode consumer tech startup headquartered in Wilmington, Delaware (USA). We are focused on building an innovative, service-based tech product designed to solve real-world problems. As a stealth startup, we intentionally maintain a low public profile while we develop and refine our product, protect our intellectual property, and build our founding team. Matriosh is currently in the beta development stage, where we are testing features, improving functionality, and preparing for a strategic launch. Our long-term vision is to create a scalable, high-impact technology platform with strong market potential. The company is led by Co-Founder & Advisor, Akaash Pandya, along with a growing executive team. We operate fully remotely and are actively hiring interns, advisors, and future co-founders to support operations, investor relations, and strategic growth. Our culture is collaborative, non-hierarchical, and impact-driven, giving every team member the opportunity to contribute ideas, work closely with leadership, and gain real experience in a fast-growing startup environment. Our goals for the upcoming phases include: Completing the beta version Securing early-stage funding Launching the platform Scaling operations, partners, and user base Moving toward profitability and potential IPO/acquisition

MAXimize Your Brokerage Business with Smarter Solutions Transform the way you do real estate—starting today.

DharmikVibes is a community-driven spiritual and wellness experience company and phygital platform. We are building the trust layer for India's spiritual economy: Divine Experiences, spiritual and wellness content, and local communities, connected in one ecosystem for seekers in India and abroad. What we are building: - Divine Experiences: satsang, kirtan, pujas, darshan, rituals and heritage, with clear information on when, what and how - Wellness experiences and content: calm, meditation and mindful routines (wellness.dharmikvibes.com) - DharmikGuide: bringing local pandits, guides and experience providers online as micro-entrepreneurs - DharmikHubs: physical local anchors for community, learning and services - Spiritual stories and content in English, Hindi and regional languages (blog.dharmikvibes.com) - Curated experiences for NRIs, senior citizens, Gen Z, women and families Our vision is to enable 1M+ micro-entrepreneurs and local livelihoods around India's sacred places, with trust, experience and economy designed in. Hiring: we are growing fast across sales, relationships and operations. Write to [email protected].

At 4Catalyzer we strive to transform 21st century medicine by solving today’s most challenging problems – across life science research tools, medical devices and therapeutics. We aspire to create significant societal impact and are motivated by the idea that our products will change the lives of people we love. Fundamentally, we are focused on developing new types of sensors and pairing them with deep learning to get a window into biology and medicine that nobody has ever had before. We have audacious plans – but we have an unbeatable team and a founder that has disrupted biomedical science successfully more than once. If you have experience in image reconstruction, mixed-signal IC design, high-speed electronics, nanophotonics, microfabrication, MEMs, biophysics, biochemistry, molecular biology, deep learning, cloud computing, embedded systems, or hold any dual degree with distinction along with computer science please contact us and “put a dent in the universe”.

Amazon Web Services provides a highly reliable, scalable, low-cost infrastructure platform in the cloud that powers hundreds of thousands of businesses in 190 countries around the world. With data center locations in the U.S., Europe, Singapore, and Japan, customers across all industries are taking advantage of our low cost, elastic, open and flexible, secure platform.

Ursa Major was founded to address a critical shortfall in the U.S. industrial base and bring a new model to aerospace and defense systems: we design and manufacture the world’s leading propulsion systems for space, hypersonic applications, and missile systems. Our products and technologies require an extraordinary team – a team that will mold tomorrow’s technologies while deploying today’s best. We are an intrinsically motivated team that has a passion for solving problems and empowering each other every day to develop our skills, knowing that there is always room for growth.