Top Tech Startups in San Francisco, CA in 2026

Madison Reed (madison-reed.com) is an e-commerce start-up with a team of 180+ rock stars in San Francisco. We’re revolutionizing the $50B hair care market using technology (web, mobile, tablet, social) to radically innovate the user experience and business model. Madison Reed is headquartered in SF and backed by top-tier venture capital firms Norwest VP, True Ventures, Maveron and Shea Ventures.

Hi! I'm Benji, the Co-Founder and CEO at Ashby. At Ashby, we're improving the productivity of working professionals with intelligent and powerful software. We put a lot of effort into designing products that are approachable to beginners but mastered & extended by power users. In many ways, spreadsheets set the bar here. Our first products provide talent teams with clever automation, powerful analytics tools, and customizable workflows packaged in great UX. We haven't launched publicly, but we have many paying customers who love us and use us every day like Opendoor, Airtable, Duolingo, and Notion. Notion's Head of Talent said Ashby is "probably the tool we are in the most and rely on the most, as a recruiting team." Our culture is motivated by Abhik's (my co-founder and Head of Engineering) and my belief that a small talented team, given the right environment, can build a great product and service fast (and work regular hours!). We hire exceptional people and provide an environment where we can be happy, feel challenged, and do our best work. We are well funded and backed by great investors, including Y Combinator, Elad Gil, and Lachy Groom. We'll share more once we meet!

Sardine helps fintech, crypto, and web3 companies "move money confidently" by developing fraud, compliance, and payment infrastructure. With Sardine, builders can focus on growing their business instead of spending time, fighting against fraudsters. We're growing incredibly fast and powering over 100 customers around the world like Brex, MoonPay, Bakkt, Luno, Transak, Chippercash, Candy Digital, Metamask, Brave, and RelayFi.

At Mixpanel, our mission is to increase the rate of innovation. Not only as a company, but for the businesses we serve. Through our analytics platform, companies can analyze how and why their users engage, convert, and retain in real time across web, mobile, and smart devices. Then they can use that data to improve their business and products.

Check is a payroll-as-a-service API that lets you embed payroll directly in your vertical SaaS, HR, or time-tracking platform. Our API abstracts away the complexities of running payroll: tax calculation, remittance, and filing, plus the movement of money between companies and employees. This enables companies to easily build fully integrated payroll products to offer to their customers. Check believes in a future where small business owners don’t have to think about payroll — it’ll simply be embedded in the platforms they already use to run their businesses. With the strong tailwinds of (1) the rise of vertical software and (2) the growth of embedded fin-tech at our back, Check is building the infrastructure to power that future, and ultimately we believe we’ll enable thousands of new platforms, millions of businesses, and hundreds of millions of workers.

For many organizations, the most valuable asset is their data. Whether source code, product designs, customer records, financial results, or pricing models, every organization has information they don’t want to get in the hands of competitors, sold on darknet marketplaces, or exposed publicly. Keeping that data safe has been a challenge, until now. Cyberhaven gives organizations the tools to safeguard their data from theft or misuse. In the process, we’ve become the standard for Data Detection and Response (DDR), the category we helped create.

Domino powers model-driven business for the world’s most advanced enterprises, including over 20% of the Fortune 100. Our Enterprise MLOps platform speeds up the development and deployment of data science work while increasing collaboration and governance, to scale data science into a competitive advantage. Our platform enables thousands of data scientists to develop better medicines, grow more productive crops, adapt risk models to major economic shifts, build better cars, improve customer support, or simply recommend the best purchase to make at the right time. Domino is backed by leading venture capital firms: Sequoia Capital, Bloomberg Beta, Coatue Management, Dell Technologies Capital, Highland Capital Partners, In-Q-Tel, and Zetta Venture Partners.

About Eight Sleep Eight Sleep is building an end-to-end predictive health platform, starting with the one place humans spend a third of their lives - the bed. Founded in 2014, we began by reimagining sleep as a trainable input to health and performance. Our flagship product, the Pod, turns the bed into an always-on lab, combining advanced temperature regulation, biometric sensing, and AI to optimize recovery, improve performance, and surface early signals for preventative action. Today, Eight Sleep has analyzed 1B+ hours of sleep data, serves customers across 30+ countries, and has recently raised an additional $100M to expand beyond sleep optimization into broader health prediction and intervention. Backed by leading investors including Founders Fund, Y Combinator, Valor Equity Partners, and HSG, we’re building the foundation for how people understand and improve their health every day - passively, continuously, and proactively. Learn more at eightsleep.com

Brex is building a first-of-its-kind solution to integrate the financial services and software that businesses need to be successful. While they build the future, we’ll be building everything they need to launch confidently and scale smarter. We are a hybrid company, optimizing for flexibility and connection. Our employees work remotely while coming to the office for a few coordinated days per week. We have offices in San Francisco, New York, Seattle, Salt Lake, Vancouver BC and Sao Paulo.

Faire was founded in 2017 on the belief that the future is local. We’re helping independent entrepreneurs chase their dreams by building an online wholesale marketplace that connects local retailers with thousands of emerging and established brands. Our platform empowers independent retailers with the advantages of big-box terms, and helps independent makers build and simplify their wholesale business.