Top Tech Startups in Maryland, US in 2027

Frame is the missing link on the family-building journey. Frame’s concierge model extends the care of in-person clinics by providing patients with 1:1 personalized support, telemedicine and coaching. Inspired by the challenging fertility journey of its wife/husband co-founders, Jessica and Corey, Frame was built alongside women’s health and fertility experts to improve patient and clinician satisfaction, operational efficiency and clinical outcomes.

Machinio.com is one of the world’s largest platforms connecting buyers and sellers of inventory and related services across multiple industries. Founded in 2013 and acquired in 2018, Machinio now serves over 4,000 paying clients globally and continues to expand its reach and impact. Thousands of dealers and suppliers rely on the platform to market and sell their equipment, connecting them with millions of prospective buyers each year. Machinio is widely recognized for leveraging technology to simplify and modernize the buying and selling process. By introducing innovative tools and improving marketplace efficiency, the company has helped both buyers and sellers save significant time while facilitating high-value transactions worldwide. Machinio System is Machinio’s all-in-one software solution built specifically for dealers and service providers. Launched in 2018, it combines modern, fully customizable, SEO-optimized websites with a fully integrated CRM platform for dealers. This unified solution enables businesses to manage their entire workflow in one place — including inventory, lead management, quoting, invoicing, contact databases, email marketing campaigns, and more. With continuous feature development and a strong product roadmap, Machinio System empowers dealers and service providers to maintain a professional online presence, leverage intelligent sales and marketing tools, and consistently generate and nurture business opportunities. Machinio has been featured in leading media outlets including Forbes, Business Insider, Inc., EquipmentWorld, Agriculture.com, and others.

Mindgrub fuses creative and technical expertise in Mobile Application Development, Web Development and Social Media. We build custom software along the critical path of singularity. We leverage hardware disruption, content management systems, education technology, augmented reality, gamification and user-centric design. Mindgrub finds and implements innovative solutions for enterprises using platforms and technologies such as iPhone, iPad, Android, and Drupal. Serving both domestic and international clients, Mindgrub is headquartered in Baltimore, Maryland with offices in Boston, New York City, Philadelphia, and Washington DC.

KamiwazaAI provides an AI platform that enables enterprises to deploy AI solutions across various environments, including cloud, core, and edge. The company's GenAI Engine facilitates the integration of private AI with private data. KamiwazaAI focuses on novel technologies like Inference Mesh and Distributed Data to support enterprise AI applications.

Quantum computing has the potential to impact every area of human society for the better--our goal is to build computers to redefine industries like medicine, materials science, finance, artificial intelligence, machine learning, cryptography, and more.

The only conversational AI platform for Self Storage. When others close their doors at 6PM, you’re still open. 24/7 in fact. You’d be surprised at how many people are looking to rent storage units at 2AM. The goal of automation should be to make the lives of people easier—whether those people are your customers or your facility manager. Automation eliminates repetitive and tedious tasks—freeing up people to spend their time on more worthwhile activities.

Kyra is a creator first company. We help the world's best creators work with the world's best brands, powered by our proprietary data platform Kyra IQ.

We built a nationwide legal services platform that helps law firms and pro se parties gain access to more efficient, transparent, and accessible legal services that are not traditionally available. Our main services are Service of Process and E-Filing .We currently serve over 2,000 law firms throughout the US, as well as countless pro se parties.

Saddle Up AI is a digital marketing agency built for the trades. We work exclusively with MEP contractors (plumbing, HVAC, and electrical companies) and help them turn online searches into booked calls. What we do: - AI-built websites designed to turn visitors into calls - Google Ads and Local Services Ads (LSA) - Meta (Facebook & Instagram) Ads - SEO and local search visibility Contractors are great at what they do, but most don't have time to run their own marketing. We handle it end to end so owners can focus on running jobs while we keep the phone ringing. We're a remote team and we're growing. If you like working with small business owners, selling real results, and getting rewarded for performance, we'd love to hear from you.

Hallak & Co. is the company behind O.S.C.A.R.™ Proprietary Operational Execution Infrastructure. O.S.C.A.R.™ establishes ownership, accountability, decision structure, KPIs, reporting and leadership cadence across organizations as growth, AI, automation and new ways of working increase operational complexity. Developed from nearly three decades of firsthand business-building and operating experience, O.S.C.A.R.™ is designed to strengthen how organizations execute across teams. Hallak & Co. is expanding O.S.C.A.R.™ through client organizations and a network of experienced Independent Executives, while building the foundation for a future O.S.C.A.R.™ SaaS platform.