Top Digital Health Startups in 2027

One in two people experience debilitating back, neck, shoulder, or joint pain — but traditional treatments have failed to meet their needs. Physical therapy can be expensive and hard to access; appointments often involve long commutes and missed work. Making matters worse, unresolved pain can trigger the overuse of opioids and surgeries. We’re making high-quality care accessible by pairing wearable sensors and computer vision with a world-class clinical team. Hinge Health puts a digital clinic in every member's pocket. Now millions of people can access personalized digital care from a physical therapist, guidance on behavior change from a health coach, and expert consultations with an orthopedic surgeon. With a single app and wearable technology like our Enso device, we’re helping to reduce pain, surgeries, and opioid use. Join us in reimagining healthcare from the ground up and empowering people to move beyond pain.

Needing to see a doctor is hard. Getting care shouldn't be. Luma's Patient Success Platform™ unifies and automates each of a patient's healthcare journeys -- access & operational, clinical, and financial -- to help them be healthier. It integrates with more than 80 EHRs to give staff and clinicians a fuller view of the patient with less manual outreach. With Luma, healthcare organizations see an average of 37% more referred patients in the first six months, and achieve a 39% average revenue increase.

The Verse: Building Games That Heal **THE VERSE OVERVIEW**: The Verse creates games, experiences, and rituals that uplift humanity. **WHO WE ARE:** The Verse is a global community of inspired gamers, developers, designers, scientists, artists, visionaries, teachers, and students who join together to passionately contribute their wide-ranging expertise to invent experiences that enhance human flourishing. **MISSION:** Our mission is to collaboratively create digital therapeutics and experiences that are playful, embodied, and ritual-enriched, that invite co-creation and foster participation and that enhance health, improve well-being and raise consciousness.

Our story started when our co-founders, whilst working as medical doctors, recognized that the holistic textbook version of medicine was not at all what was being provided for patients. The reality is that a stretched healthcare system fails to engage people in their medical care at the preventative stages. As a result, the $3 trillion currently spent on healthcare goes on to prevents only 10% of premature deaths. With digital therapeutics, we have the opportunity to prevent 40% of premature deaths that are caused by behavioral patterns. Quit Genius is a behavior change platform that combines digital coaching, personalized content, wearable technology and medication to help people overcome addictive behaviors.

Carrot Fertility is the leading global fertility care platform, serving people of every age, race, income, sex, sexual orientation, gender, marital status, and geography. Trusted by hundreds of multinational employers, health plans, and health systems, Carrot's comprehensive clinical program delivers industry-leading cost savings for employers and award-winning experiences for millions of people worldwide. Whether there is a need for care through fertility preservation, male-factor infertility, pre-pregnancy, IVF, pregnancy and postpartum, adoption, gestational surrogacy, or menopause, Carrot supports members and their families through many of the most memorable and meaningful moments of their lives. With Carrot, you can pursue your possible. Carrot has received national and international recognition for its pioneering work, including Best Diversity, Equity, & Inclusion Product from the Anthem Awards, Fast Company's Most Innovative Companies, CNBC's 100 Barrier Breaking Startups, and more. Carrot is regularly featured in media reporting on issues related to the future of work, women in leadership, healthcare innovation and diversity, equity, and inclusion, including MSNBC, The Economist, Bloomberg, The Wall Street Journal, CNBC, National Public Radio, Harvard Business Review, and more. Carrot is a remote-first company with teams in more than 40 states across the United States and dozens of countries around the world. It has received numerous workplace awards, including Fortune's Best Workplaces in Healthcare, Quartz’s Best Companies for Remote Workers, and Great Place to Work and Age-Friendly Employer certifications. Learn more at carrotfertility.com.

Spruce is a communication software platform built for independent healthcare practices. Our HIPAA-grade, cloud-based solution integrates a business phone system with texting, faxing, and telemedicine—optimizing care collaboration, streamlining patient interactions, and ensuring accountability. Trusted by tens of thousands of healthcare organizations across the U.S. and backed by over 60,000 5-star reviews, Spruce is transforming healthcare communication.

Our mission: to eliminate every barrier to mental health. Spring Health is a comprehensive mental health benefit for employers. We help employees understand their mental health issues and connect with best-in-class providers to get the right treatment at the right time. From early detection to full recovery, Spring Health is the only clinically validated solution proven to be more effective than traditional mental healthcare. By combining the latest technology with vetted providers, we help engage 1 in 3 employees, reduce recovery times, and lower healthcare costs. We are an award-winning, passionate, and mission-driven team with the support of leaders in psychiatry, and have raised $30M to date from prominent VCs including Northzone, Rethink, Work-Bench, RRE, and General Catalyst.

MedMe is building the operating system for the pharmacies of the future, powering their transformation from dispensaries to community healthcare hubs. Hi, I’m Rui and I’m the Co-Founder and Chief Clinical Officer of MedMe. I’m a pharmacist, and despite a $200k Doctor of Pharmacy degree, I still spend most of my time writing notes by hand and fielding phone calls for refills. When in fact, pharmacists can directly prescribe meds (like birth control), adjust diabetes/heart medications, give over 20 different vaccines/injections, and much more! I was almost ready to leave my profession when I met my co-founders Purya & Nick. Purya was a health data scientist for the government and Nick a product engineer for the Tesla Roadster. They’d watched their own parents struggle with managing 10+ medications and were equally passionate about using pharmacists to provide more services for patients in the community. Together, we identified the biggest problem to be existing pharmacy software built 20 years ago with the primary purpose to sell drugs. So, we built MedMe. Our mission is to build an all-in-one cloud-based platform that empowers pharmacists to schedule, document, and manage clinical services at scale. Our clients include the 2 largest pharmacy chains in Canada, servicing 3500+ pharmacies, and powering over ~20M patient services, including playing a critical role across the country throughout the pandemic. We have raised over $3.7M USD to date including from M12 (Microsoft’s Venture Fund), MaRS IAF, and Y-Combinator. We're building on our rapid growth and role throughout the pandemic to take our modular platform to the next level; providing community pharmacies of all sizes and geographies the transformative technology to service high-quality care experiences and accessible healthcare offerings to their patients.

iSono Health is developing AI-powered solutions for accessible and personalized health monitoring . Our first solution, ATUSA, combines a wearable, automated ultrasound and AI to transform breast cancer screening by increasing quality, improving access, and lowering cost. ATUSA system produces repeatable 3D images, independent of operator skill in 1min, enabling accurate and rapid diagnosis. iSono Health’s deep learning technology extracts acoustic biomarkers from quantitative ultrasound data to identify and track functional properties of breast tissue enabling early detection and monitoring of breast cancer.

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