Top Artificial Intelligence Startups in Chicago, IL

We're building the data platform to power safe and fair decisions. Checkr provides fast, accurate information to power informed decisions. Our innovative technology and robust data platform help customers assess risk and ensure safety and compliance to build trusted workplaces and communities. We’re a team that thrives on solving complex problems with innovative solutions that advance our mission. Come join us!

C3.ai is a leading enterprise AI software provider for accelerating digital transformation. The proven C3 AI Suite provides the comprehensive services to build enterprise scale AI applications 40x to 100x faster than alternative approaches. The core of the C3 AI Suite is a revolutionary, extensible, model-driven abstraction layer that dramatically enhances data scientist and application developer productivity. The C3 AI Suite supports any value chain in any industry with pre-built, configurable, high-value AI applications for predictive maintenance, fraud detection, sensor network health, supply network optimization, energy management, anti-money laundering, and customer engagement. c3.ai

Clearcover is a smarter car insurance choice. The company offers better coverage at lower prices than traditional carriers by using advanced technology, eliminating wasteful spending, and promoting transparency to help consumers make informed decisions. The company has been featured in Forbes and Inc for its innovative approach to redesigning car insurance for the everyday driver.

SourceIQ is a cutting-edge tech startup dedicated to revolutionizing supplier sourcing through automation. Our flagship product is a cloud-based enterprise solution that streamlines procurement and supplier management.

We’re an engineering company using AI to help companies collect their cash (Accounts Receivable). We're backed by a16z, Khosla, Activant, 1984 and Page One Ventures.

DISCO is the leading provider of ediscovery solutions for law firms, corporations, and government agencies. With technology and services that automate and simplify complex and error-prone tasks that distract from practicing law, DISCO empowers lawyers and their teams to effectively manage discovery processes. DISCO is the ediscovery choice of leading U.S. law firms including litigation boutiques and AmLaw, Fortune 500 companies, as well as government agencies around the world. Ready for an ediscovery upgrade? Request a demo at demo.csdisco.com.

nOps is an automated cloud optimization platform that makes it easy to allocate and manage cloud usage, commitments, and spend. Managing $4B+ in annual cloud spend, nOps helps companies of every size, from fast-growing startups to global enterprises, reclaim millions in wasted cloud costs. Cloud waste is one of the fastest growing challenges in tech. nOps tackles it by leveraging proprietary ML modeling and AI-powered automation to guide organizations toward the right commitment strategy. The platform eliminates manual provisioning entirely, delivering maximum cost savings without sacrificing reliability, so teams can focus on building and innovating. Trusted by innovative brands around the world, nOps has been recognized as a G2 Top 50 Security Product and G2 Leader for Winter 2025, is an AWS Advanced Technology Partner, and a proud FinOps Foundation Member with our CEO serving on the FinOps Foundation Governing Board.

Our mission is to make technical advances towards robots and humans working together side by side, with an emphasis on human-centric design. Diligent Robotics is developing a suite of artificial intelligence that enables robots to collaborate with and adapt to humans in everyday environments. Our first product is a hospital service robot that can assist clinical staff with logistical tasks, allowing them to spend more of their time on direct patient care, improving patient satisfaction, quality of service, and safety.

Hallak & Co. is the company behind O.S.C.A.R.™ Proprietary Operational Execution Infrastructure. O.S.C.A.R.™ establishes ownership, accountability, decision structure, KPIs, reporting and leadership cadence across organizations as growth, AI, automation and new ways of working increase operational complexity. Developed from nearly three decades of firsthand business-building and operating experience, O.S.C.A.R.™ is designed to strengthen how organizations execute across teams. Hallak & Co. is expanding O.S.C.A.R.™ through client organizations and a network of experienced Independent Executives, while building the foundation for a future O.S.C.A.R.™ SaaS platform.