Top Artificial Intelligence Startups in Chicago, IL

AssemblyAI is a remote-first company building powerful AI models for developers, startups, and enterprises to transcribe and understand their audio data. Our mission is to make production-ready, state-of-the-art AI models accessible to developers and product teams at extremely large scale through simple APIs. Customers, including Spotify, Algolia, Dow Jones, Happy Scribe, BBC, The Wall Street Journal, and NBCUniversal, use our APIs to transcribe and understand millions of videos, podcasts, phone calls, and zoom meetings every day. Our APIs power innovative products like conversational intelligence platforms, meeting summarizers, content moderation, and automatic closed captioning. We're growing at breakneck speed, and recently announced our Series B round. We've raised $63M in total funding, backed by leading investors including Insight Partners, Accel, Y Combinator, Patrick and John Collision (Founders of Stripe), Nat Friedman (Former CEO of GitHub), and Daniel Gross (Entrepreneur & Investor in companies including GitHub, Uber & SpaceX). Our team is made up of problem solvers, innovators, and top AI researchers from companies like DeepMind, Google Brain, Meta AI, Amazon and Apple. They conduct cutting-edge AI research and develop novel algorithms and techniques to continually push the state-of-the-art in speech recognition and NLP. Join our world-class, remote team and help us build an iconic deep learning company!

LogicMonitor®’s SaaS-based observability and IT operations data collaboration platform helps ITOps, developers, MSPs and business leaders gain visibility into and predictability across the technologies that modern organizations depend on to deliver extraordinary employee and customer experiences. LogicMonitor seamlessly monitors everything from networks to applications to the cloud, empowering companies to focus less on troubleshooting and more on innovation. For more information, visit logicmonitor.com. Great Place to Work Certified, 2022 Best Places to Work, Built in Austin 2022 Company with the Best Benefits, Built in Austin 2022

Clearcover is a smarter car insurance choice. The company offers better coverage at lower prices than traditional carriers by using advanced technology, eliminating wasteful spending, and promoting transparency to help consumers make informed decisions. The company has been featured in Forbes and Inc for its innovative approach to redesigning car insurance for the everyday driver.

C3.ai is a leading enterprise AI software provider for accelerating digital transformation. The proven C3 AI Suite provides the comprehensive services to build enterprise scale AI applications 40x to 100x faster than alternative approaches. The core of the C3 AI Suite is a revolutionary, extensible, model-driven abstraction layer that dramatically enhances data scientist and application developer productivity. The C3 AI Suite supports any value chain in any industry with pre-built, configurable, high-value AI applications for predictive maintenance, fraud detection, sensor network health, supply network optimization, energy management, anti-money laundering, and customer engagement. c3.ai

DISCO is the leading provider of ediscovery solutions for law firms, corporations, and government agencies. With technology and services that automate and simplify complex and error-prone tasks that distract from practicing law, DISCO empowers lawyers and their teams to effectively manage discovery processes. DISCO is the ediscovery choice of leading U.S. law firms including litigation boutiques and AmLaw, Fortune 500 companies, as well as government agencies around the world. Ready for an ediscovery upgrade? Request a demo at demo.csdisco.com.

Our mission is to make technical advances towards robots and humans working together side by side, with an emphasis on human-centric design. Diligent Robotics is developing a suite of artificial intelligence that enables robots to collaborate with and adapt to humans in everyday environments. Our first product is a hospital service robot that can assist clinical staff with logistical tasks, allowing them to spend more of their time on direct patient care, improving patient satisfaction, quality of service, and safety.

PayMaple is a best in class platform company that assists organizations to lower costs and increase profits with proprietary payment and data warehousing solutions. Our foundation is built upon transparency, and we set out to help businesses better understand how their operation is run.

Martal Group is a top lead generation & sales agency servicing B2B tech companies. We are a turnkey solution sales partner generating qualified leads, providing support staff and sales streamlining services, right through to signed contracts. Our team specializes in creating leads for SaaS, IT services and IOT vendors who cater enterprise software, location-based services, search relevance, data annotation, video analytics, consumer insights, sales performance management, cloud backup, fleet management, AI powered applications and other products. We provide managed services for outbound sales, our fractional sales executives, marketing leaders and account managers will help your team in sourcing deals, pitching prospects and winning new business. Our U.S. and Canada based executives serve as an extension of your sales and marketing team; they are sourced to fill your sales teams’ calendar with new business, accelerate your growth and fill gaps in your process. We build weekly prospect lists enriched by intent data. We target decision makers using multiple touch points - email marketing, linkedin messaging, cold calls and trade shows.

nOps is an automated cloud optimization platform that makes it easy to allocate and manage cloud usage, commitments, and spend. Managing $4B+ in annual cloud spend, nOps helps companies of every size, from fast-growing startups to global enterprises, reclaim millions in wasted cloud costs. Cloud waste is one of the fastest growing challenges in tech. nOps tackles it by leveraging proprietary ML modeling and AI-powered automation to guide organizations toward the right commitment strategy. The platform eliminates manual provisioning entirely, delivering maximum cost savings without sacrificing reliability, so teams can focus on building and innovating. Trusted by innovative brands around the world, nOps has been recognized as a G2 Top 50 Security Product and G2 Leader for Winter 2025, is an AWS Advanced Technology Partner, and a proud FinOps Foundation Member with our CEO serving on the FinOps Foundation Governing Board.

Every enterprise wants to become AI-native, but very few know how to turn rapidly evolving AI capabilities into production systems that create measurable business value. That's where Tribe AI comes in. We are an AI-native services company that helps Fortune 500 companies and ambitious startups design, build, and deploy production-grade AI systems. Our teams work directly with clients to solve high-impact problems using LLMs, agentic workflows, RAG, multimodal AI, evaluations, and modern AI infrastructure not just prototypes or demos. Unlike traditional consulting firms, our engineers, architects, product leaders, and AI specialists embed alongside client teams to understand their business, design practical solutions, and deliver systems that operate reliably in production. We're proud partners of OpenAI and Anthropic, giving us early access to frontier models and close collaboration with the teams building the future of AI. At Tribe, you'll work on challenging AI problems across industries including healthcare, finance, manufacturing, cybersecurity, life sciences, and enterprise software. Every engagement is different, which means continuous learning, meaningful ownership, and the opportunity to shape how the world's largest companies adopt AI. If you're excited about solving difficult technical problems, working directly with customers, and shipping AI systems that matter, you'll fit right in.