Top Tech Startups in United States in 2027

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SEP is a software product and design company that builds products for global, midsize and small companies. Started in 1988 and headquartered in Westfield, Indiana, SEP was created by four Rose-Hulman Institute of Technology graduates. SEP is one of Indiana’s largest software development firms with more than 180 employees. SEP partners with companies to develop software products and information systems that solve complex problems and building products that impact people’s lives. SEP serves Fortune and Global 1000 clients as well as mid-sized and startup companies.

AI-powered marketplace for diamond engagement rings moving over $100m in annual sales. Called the "Secret to Buying the Perfect Diamond" by the New York Times: nytimes.com/2018/12/07/your-money/diamond-comparison-shopping.html

Limit provides software, digital wholesale brokers, technology, sales, and data services for commercial insurance. The company was founded in 2020, and is based in San Francisco, California, United States.

PatientPop is a fast-growing healthcare technology company with $75 million in funding. PatientPop has one simple mission: to help healthcare practices thrive. We do this by giving providers everything they need attract and recall patients to continuously grow their practices. With PatientPop, providers can attract more patients, manage online reputation, modernize the patient experience, and automate the front office — all without sacrificing quality patient care. We've helped thousands of providers since our founding in 2014. Along the way, we cultivated an incredible work environment — one of the best, according to Great Place to Work.

Turntide Technologies is helping turn the tide on climate change with a revolutionary Platform for Sustainable Operations that drives down energy consumption and operating costs in buildings, agriculture, and electric transport. Our patented hardware and intelligent software are revolutionizing the $100 billion electric motor industry with a new platform so efficient, reliable, and adaptable that it reduces energy use by more than half. Our larger mission is to replace all the world’s motors with intelligent, optimal-efficiency systems so every watt is worthwhile for humanity. We’re looking for curious, intelligent, collaborative people from diverse backgrounds who want to make a real impact on the sustainability of our planet.

Bizwise builds AI tools that help small businesses launch, sell, and operate. Customers use our automated site generator, visual editor, and commerce features to run day-to-day.

Store and query unlimited machine data with Axiom’s serverless, cloud native data insight platform. Logs, events, metrics, etc - no matter what kind of machine data, Axiom is the place to store and query it. Gain immediate insights with our analytics feature, stream events live, create dashboards, and use alerting to have continuous monitoring. Built by engineers for engineers, Axiom is 'fire-and-forget' for any kind of data.

Stronghold creates virtual payment networks that enable instant settlement and interoperability between legacy and new payment networks. Check us out! youtube.com/@Strongholdpay/featured

We are building a world where no patient has to die of cancer. Our FDA-cleared flagship product, Unfold AI, reveals the invisible cancer that doctors miss, enabling oncologists and surgeons to achieve better treatment outcomes while preserving patients’ quality of life. Unfold AI is a multi-modal AI platform that combines a patient’s diagnostic data together (from EHR, PACS, and other healthcare systems) to create an interactive 3D map of the patient’s cancer, enabling more precise and personalized treatment. Unfold AI improves the ability of expert oncologists and surgeons in finding and eliminating cancer, demonstrated in multiple clinical trials.