Top Tech Startups in San Francisco, CA in 2027

Highnote is the world’s most modern card platform, purpose-built to grow customer loyalty, engagement, and revenue through embedded card issuance experiences. With an all-in-one platform and a fully integrated issuer processor built from scratch to address the use cases of today and tomorrow, Highnote gives enterprises unparalleled control, flexibility, and speed to realize their customer vision through innovative embedded finance experiences. Utilizing the developer-friendly Highnote platform, product and engineering teams at digital enterprises of all sizes can easily and efficiently embed virtual and physical payment cards (commercial and consumer prepaid, debit, credit, and charge), ledger, and wallet capabilities into their existing products, creating compelling value for users while growing revenue and building a unique and differentiated brand.

Amazon is guided by four principles: customer obsession rather than competitor focus, passion for invention, commitment to operational excellence, and long-term thinking. We are driven by the excitement of building technologies, inventing products, and providing services that change lives. We embrace new ways of doing things, make decisions quickly, and are not afraid to fail. We have the scope and capabilities of a large company, and the spirit and heart of a small one. Together, Amazonians research and develop new technologies from Amazon Web Services to Alexa on behalf of our customers: shoppers, sellers, content creators, and developers around the world. Our mission is to be Earth's most customer-centric company. Our actions, goals, projects, programs, and inventions begin and end with the customer top of mind. You'll also hear us say that at Amazon, it's always "Day 1."​ What do we mean? That our approach remains the same as it was on Amazon's very first day - to make smart, fast decisions, stay nimble, invent, and focus on delighting our customers.

At Paystand, we’re not just another fintech company—we’re trailblazers in decentralized finance (DeFi), transforming how businesses manage their finances. With thriving hubs in Santa Cruz, San Francisco, Austin, Minneapolis, Mexico City, Hermosillo, and Guadalajara, we’re leading a global revolution in financial systems. Recognized on the Inc. 5000 list for five consecutive years, we’re among the fastest-growing companies reshaping the future of finance. Our Expanding Ecosystem: Paystand isn’t just a company—it’s a growing global network. With the strategic acquisitions of Teampay, a leader in spend management, and Yaydoo, a top AR and AP platform in Latin America, we’re building an expansive ecosystem designed to revolutionize financial operations and fuel business growth worldwide.

Sleeper's mission is to connect people over sports. We believe the most important aspect of sports is its ability to bring friends and communities together. We do this via multi-player games like fantasy leagues, with messaging at the core of the experience. We're hiring and would love to meet you!

Keeper is an AI-native tax filing software, designed for people with complex taxes. Connect your bank to automatically uncover hidden tax breaks!

Chowbus is a food ordering platform which curates featured dishes from selected ethnic restaurants daily and delivers them fresh and hot to your home or office affordably with the tap of your cell phone. We provide dish-centric mobile ordering experience for consumers to easily explore and order authentic ethnic food and we empower local ethnic restaurants with the technology, tools, and marketing to grow their business.

We are providing a complete “business in a box” solution for owner-operators and small trucking carriers at a much lower cost using software engineering, data science and world class operations processes. Our mission is simple — to put more money in the hands of truck drivers and reduce their headaches. CloudTrucks will improve the three core metrics that every truck driver cares about — revenue, cash-flow and costs. We focus on the owner-operator and small trucking companies because they are the lifeblood of the industry and facing the largest pressures with fast rising insurance rates, predatory factoring options and a quickly changing landscape. It’s more important than ever to have someone in their corner whose incentives are 100% aligned with theirs.

Waste collection in the US is a 100 billion dollar industry that underpins the daily lives of every person and business. If successful, our software will simultaneously drive more sustainable waste processing practices and profitable economics for thousands of small and medium waste haulers, a win-win for planet Earth and SMBs.

At Sprinter Health, we’re tackling one of healthcare’s biggest challenges: reaching patients who have fallen through the cracks of our healthcare system. With a boots-on-the-ground clinician network and the tech platform to solve this problem at scale, we bring critical preventive care to folks who are otherwise not getting it, whether due to disability, socioeconomics, transportation insecurity, or simply not getting around to it. We believe that access to healthcare shouldn’t be so hard, and by making it easier for folks to get the diagnostics and preventive care they need, we can halt the growing tide of disease and healthcare costs in America. Since launching in 2021, we're now live across 15+ states, covering over 60% of the US population and partnering with 6 of the 10 largest U.S. health plans. We've served >60k patients in-home from ages 3 to 103. And with 5x revenue growth in 2023 and 6x growth in 2024, things are only accelerating. Our team of technologists, clinicians, and operators bring decades of experience from Google, Meta, Amazon, Epic, Aetna, and Oak St. Health. And with over $125M raised from top VC investors, including a16z, General Catalyst, GV, and Accel, we have everything we need to transform healthcare. Jobs at Sprinter Health We're looking for strong engineers and product managers at all levels who want to make an impact today. We want to change lives—save lives—and we could use all the help we can get. If you want to build things, we want to talk to you. If you want to grow faster than you ever could at a big company, we want to talk to you. If you want to make a difference, we want to talk to you.

Nash enables businesses to reliably deliver. The company exists to democratize local delivery for business across all industries and sizes. Nash uses the power of technology to build user-friendly infrastructure and smart interfaces that enable all merchants to exceed the rapidly evolving expectations of today and tomorrow's consumer.