Top Tech Startups in New England, United States in 2027

> Why Castle? So many Americans dream of owning a home but face a harsh reality once they get there. Maintenance, repairs, and running costs can leave many homeowners even more stressed, strained, and financially insecure than they were before. We believe that homes can still be incredible sources of wealth and security for millions of Americans, but that homeowners deserve better data to make better choices when it comes to managing their biggest asset. That’s why Castle is building payments infrastructure for the $3T spent on the home each year — starting with a bill-pay mobile app to help homeowners automate, consolidate, and reduce their spend. > Why you? We want to work with talented, curious, and creative people with many different experiences and perspectives who care deeply about our customers and want to help them solve real problems. A sense of humor and love of dim sum are a bonus. If that sounds like you, we want to work with you.

A new kind of CRM.

Layer Health is a health technology company that utilizes AI and large language models to streamline medical chart reviews. Layer Health's AI platform uses large language models (LLMs) trained on extensive patient data over time. This technology enables healthcare systems to analyze and interpret both structured and unstructured clinical information with an accuracy comparable to that of clinicians. In contrast to conventional software solutions that predominantly depend on fixed rules, Layer Health’s AI operates with a reasoning approach akin to that of a clinician, allowing it to navigate highly nuanced and intricate situations throughout a patient's complete medical record.

AI Business Boomer is an implementation-first AI automation service led by Sam Monac. We help small business owners and operators use practical AI systems to save time, respond to leads faster, reduce manual admin, and make day-to-day operations more repeatable. Our work is not abstract AI consulting. We build useful workflows around real business bottlenecks: missed calls, slow follow-up, invoice reminders, intake forms, scheduling, customer communication, reporting, websites, and operational handoffs. Interns joining AI Business Boomer work close to real business problems, live tools, customer-facing pages, automation workflows, content systems, QA, research, outreach, and growth operations. The work is hands-on, fast-moving, and useful for candidates who want practical experience building with AI instead of only talking about it.

US Staffing Company

EliseAI is an AI startup transforming complex healthcare and housing systems. By deeply integrating into workflows and automating operations, it makes them efficient and cuts costs for all. Its platform supports medical practices with patient scheduling, intake and front-desk operations and helps property managers handle leasing, maintenance and resident engagement. EliseAI replaces fragmented tools with one integrated system that reduces manual work and improves accessibility and experience for residents and patients alike. The company is based in New York with teams in San Francisco, Boston and Chicago. To learn more, visit eliseai.com/careers.

We’re a squad of fintech builders, powered by Stripe, on a mission to shatter old remittance and banking limits and unleash instant cross-border payments for the Caribbean and Latin America’s business and community landscape. Whether someone is sending funds from Toronto, London, or Miami, or spending it in Kingston Jamaica (our first country), our closed-loop ecosystem gets money moving fast, locally, and for real impact.