Top Tech Startups in Los Angeles, CA in 2026

RDI is an overnight success — years in the making. We’re scaling fast (grew 4× last year), fueled by enterprise engagements with the top IVD manufacturers in the world. For a small team, we punch way above our weight. RDI has become the go-to CRO for large public diagnostics companies who rely on our creativity, tech-forward systems, and zero-excuses accountability to get trials done quickly and done right. We’re a fully integrated IVD CRO — a high-complexity CLIA lab, a technology-enabled CRO, and a national physician + lab network under one roof. This lets us run clinical trials with a level of speed and operational precision the industry isn’t used to. RDI was founded in 2008 and professionalized in 2017 through a search fund acquisition (not venture hype). We’re backed by long-term operators and growth investors — not dependent on VC burn or fundraising cycles. From 2022–2024, we expanded aggressively by doing the hard things right: building real infrastructure, earning trust from enterprise customers, and executing consistently. Our physician network was sourced from real insurance claims data and strengthened by CAP accreditation. No one has successfully started and scaled a modern CRO focused on diagnostics and medical devices in over 15 years. The industry is dominated by large, slow incumbents optimized for pharma — not speed, accountability, or precision. We’re the underdog — and we’re winning. Our goal is simple: prove our customers right, and prove the industry wrong. Get a feel for how we work: youtube.com/watch?v=3tccEbsWIl8

Built for the most demanding enterprise workloads, from AI and HPC simulations to Splunk Observability, genomics and PACS medical imaging, geospatial datasets, media editing and rendering, and video surveillance, the Qumulo Data Platform unlocks the full power of an organization’s information. It is a unified global file system solution that spans data centers, edge, and public clouds, enabling efficient, accelerated computing and extending the reach of data unbound by protocol or transport limitations.

A personal fitness service that combines certified personal trainers, mobile apps and cloud technology to deliver fitness results. How it works: - Meet your trainer in-person, 1-4x each month. - Get personalized, guided mobile app workouts from your trainer. - Stay connected, motivated and accountable, 24/7. GAIN Trainer Network - Highly vetted, expert certified personal trainers - Diverse network spanning multiple fitness specialties in select geographic markets GAIN Clients App - Best-in-class guided workout experience - Performance tracking of exercises, sets, reps - 2,000 exercise instruction multimedia & detailed database developed by top fitness experts GAIN Trainers App - Personalized workout program building tools - Suite of client management & communication tools - In-person meeting scheduling & verification system

In an increasingly digital world, MemoryWell is solving a growing list of healthcare’s most challenging engagement problems with an unexpected solution: Empathetic, human interaction. Our solutions make the person the center of healthcare. MemoryWell delivers dramatic increases in satisfaction and retention. And our rich, person-centered dialogs yield the most accurate SDOH and HRA data available. MemoryWell grew out of the experience our founder, Jay Newton-Small, had caregiving for her father, who had Alzheimer's. When she moved him into a senior community, she was asked to fill out a long questionnaire about his life. This made no sense: who would remember pages of hand-written data points for 100+ residents in that community? Instead, as a longtime TIME Magazine correspondent, she wrote his story for his caregivers and pasted it on the walls throughout the community. It transformed his care. Two of his caregivers were Ethiopian and they'd had no idea Jay’s father, Graham, had lived in Ethiopia for years early on in his career with the United Nations. They became his champions, sitting for hours asking him about what it was like to work with Emperor Haile Selassie. Seeing the impact her story had on her father’s experience was enough to influence Jay to transition from her role at TIME to launch MemoryWell. In addition to the life stories product, MemoryWell has leveraged insights and journalistic engagement to reduce churn in Medicare Advantage. Medicare Advantage churn averages 10% and is as high as 40% during the first 90 days. Enrollees have grown numb to automated texts and robocalls, resulting in expensive data gaps. MemoryWell provides human-to-human engagement that resolves these problems with skillful conversation, relationship building, and education.

Aphid is a global automation network for people and businesses to utilize artificial intelligence bots.

Kyra is a creator first company. We help the world's best creators work with the world's best brands, powered by our proprietary data platform Kyra IQ.

Whippy is the AI platform built by a professional poker player turned two time founder, bootstrapped past 1,000 customers with zero VC money, profitable, and growing fast. We build AI agents that answer calls, screen job candidates, and run entire workflows for businesses across the country. Our customers save millions per year and our named case studies prove it. Our engineering team is bigger than the rest of the company combined, and our sales motion is founder led, which means early hires work directly with the CEO, not three layers below him. We use AI to run our own company the way we sell it: every hire here automates their own job first. We hire for slope, not pedigree. The people who join early get handed real ownership fast: our last off script hire now runs an entire function. If you outwork everyone around you and want to learn how a real business runs from inside every decision, this is the place.

Fullcourt is driving the digital transformation of the basketball community. Creating a marketplace organizing games and events, while building tools to help small basketball businesses and services.

We collaborate with startups and industry leaders around the world to invent and reinvent the products of tomorrow. From branding to UX/UI design to custom web and mobile app development, we give meaning and feeling to budding businesses.

Vend is a SaaS payments company leveraging AI and automation to elevate parking into a first-class mobility vertical