Top Tech Startups in Buffalo, NY in 2027

KeepTruckin is a San Francisco-based company that serves more than one million drivers and over 100,000 businesses that power the physical economy by equipping them with the technology needed to improve the safety and efficiency of their operations. Shoaib Makani and his co-founders Ryan Johns and Obaid Khan founded the company in 2013 to serve the trucking industry, a workforce that is essential to the economy but underserved by technology. Today, KeepTruckin’s 400,000-strong network of connected vehicles, ranging from small trucking companies to Fortune 500 enterprises, is one of the largest in North America. The products that KeepTruckin builds deliver integrated value for a diverse range of industries, from construction and oil and gas to distribution and moving and storage. At every turn, KeepTruckin provides cutting-edge hardware and software that leverages the latest advancements in AI and computer vision to solve a broad range of problems for businesses with vehicles — spanning video-based driver safety, Electronic Logging Device (ELD) compliance, GPS tracking, dispatch, and fuel and maintenance. KeepTruckin’s series E round valued the company at $2.3 billion, and it currently employs more than 2,400 people worldwide.

AMPAworks is a team of doctors, nurses, and engineers who have built an IoT system leveraging computer vision deep learning to monitor and re-order inventory in hospitals. We provide real-time data that saves the average hospital $10million annually by automating manual inventory enumeration tasks.

About Zenskar Zenskar is an AI-native revenue automation platform built to handle real-world complexity. It sits between your CRM and ERP and automate everything in between: billing, revenue recognition, collections, usage metering, and analytics. Across any pricing model, any entity structure, any currency. Our vision: Zero-Touch: Finance. Agents execute. Humans supervise. Finance teams set the rules. Zenskar runs them. Founded by [Apurv Bansal](linkedin.com/in/bansalapurv) and [Saurabh Agarwal](linkedin.com/in/saurabh--agrawal), second-time founders whose previous startups were acquired by Snapdeal and Gaana. The team brings experience from Google, Deutsche Bank, Elevation Capital, Harvard Business School and IITs. We have 5x'd revenue in the past year.

Saddle Up AI is a digital marketing agency built for the trades. We work exclusively with MEP contractors (plumbing, HVAC, and electrical companies) and help them turn online searches into booked calls. What we do: - AI-built websites designed to turn visitors into calls - Google Ads and Local Services Ads (LSA) - Meta (Facebook & Instagram) Ads - SEO and local search visibility Contractors are great at what they do, but most don't have time to run their own marketing. We handle it end to end so owners can focus on running jobs while we keep the phone ringing. We're a remote team and we're growing. If you like working with small business owners, selling real results, and getting rewarded for performance, we'd love to hear from you.

HelixIntel is on a mission to help insurers move from paying for losses to predicting and preventing them. HelixPrevent turns real maintenance activity into risk intelligence carriers can underwrite against, giving insurance partners visibility into equipment condition, maintenance discipline, and emerging failure risk across their books, long before a claim is filed. That intelligence is powered by HelixCMMS, the maintenance platform their insureds use every day to stay organized and proactive.