Top User Interface Design Startups in 2026

Koda Health is a fast-growing digital health startup that leverages AI to help guide difficult conversations in healthcare, starting with end-of-life care planning. Our platform helps patients express and document their medical care preferences - ensuring patients receive the care they want and curbing the financial burden in the last years of life. Koda Health is a graduate of multiple prestigious startup development programs including TMC Biodesign, Techstars UnitedHealthcare Accelerator, and Lighthouse Labs. As a venture-backed company, Koda Health is committed to enhancing quality, cost, and access to care and to improving the experience for all our stakeholders to make health care work better for everyone.

Since 2002, we’ve had over 1.2 million enrollments and helped people fast-track their careers and make a meaningful difference, while supporting millions more through open-source content. We collaborate with over 250 leading designers from Google, NASA, Harvard, and Adobe to make world-class learning accessible. We are a fully remote company, bringing together exceptional talent from across the globe. Read more about our values, company culture and open positions: ixdf.org/about

Rhombus is a Silicon Valley startup and NASA Research Park partner. We are leaders in bringing big-data insights to Enterprise planning and decision-making at strategic, operational and tactical levels. Our advisory board includes two Nobel Laureates and a Draper Prize winner. We choose to solve pressing problems in National Security and Energy sectors using cutting edge cross-disciplinary approaches. Are you ready to help the US win the AI race?

Archesys provides a wide range of technical services and has been doing so for over 20 years, making a significant impact in the areas of organization, culture, and technology in both the private and public sectors. From digital modernization to process management, our team is the go-to resource for various government agencies looking to improve or overhaul their operations.

Alo Yoga is making the best yoga clothing in the world explicitly to inspire yogis.

Anime Universe is a story about us, our industries, the people we love and what they care about. It will be a fully immersive, safe and trusted environment where we will find a space for ourselves and our communities to create new memories and share our activities.

Orium (formerly known as Myplanet) is North America's leading consultancy and systems integrator specializing in composable commerce, customer data, and retail platform engineering. We have over a decade of experience in digital programs, and we work closely with best-in-class technology partners to bring modern commerce experiences to life as a member of the MACH Alliance. We're a remote-first company of over 200 globally-distributed employees. We've been a certified BCorp for over a decade. Based in Toronto with a global studio presence, we draw from a range of talents and perspectives to bring together data, systems thinking, and curiosity to build next-generation experiences. We’re building deep capabilities in data-driven design, AI implementation, and personalization while forming strong partnerships with leaders in machine learning, hardware development, and IoT platforms.

Deploy your idea into the market faster with a prototype-first strategy. Two Words is a design first company that enables businesses to grow faster. In a way, we assist in creating a world of illusion through prototyping, which involves making what appears to be a product but not getting inputs and opinions on whether your ideas are viable further. If not, the prototype’s responses will indicate a better development path.

We offer our clients a variety of end-to-end app design & development services including: - Strategy - Startup Branding - UX/UI Design - iOS Development - Android Development - PHP/MySQL Development - GraphQL Development - Flutter Development - React Native Development

We are a Forward Thinking Digital Innovation partner creating impactful business outcomes with Engineering & Experience. We are a leading Digital Transformation Services Company based out of US and India. We take a consultative solutioning approach towards digital transformation and product development using cutting edge technology, everlasting user experiences and innovation. Services Verticals: - Cloud Consulting & Adoption - Custom Application Development - Mobile Application Development - Microservices & ServerLess Development - AI & Machine Learning Development - Microsoft Dynamics & Power Apps Development - Salesforce Development - User Experience Design Services Our Strategy and Innovation practices reflect in steering our customers solutions in the right direction. Providing effective idea conceptualization, market-reseach, gap-analysis, road-mapping and LEAN Product Management helps our customers achieve the most of their developed products. Gleecus is ambidextrous when it comes to Technology and Experience creation. Our teams deep tech knowledge and expertise in empathetic user-experience brings the best of both worlds to our customers’ business and its users. We are Process Oriented. As simple as that. However we do not apply the “one size fits all” approach. We have identified LEAN management as our style of development, delivery and support. We keep our processes simple and transparent to keep our customers informed on a near-realtime basis and reduce development and delivery cycles. Following a Continuous Delivery and Integration practices we keep shipping features from Staging to UAT to Release in a swift manner.