Top Software Startups in North America

John Fisher (Founder & CEO) and Cody Fisher (Co-Founder & COO) are the father and son entrepreneurial team behind CBD Pros USA. When Cody was young, John brought him along on many business trips, especially during his early days as a successful franchisee in the automotive products industry. Cody learned at a young age how to maneuver through the intricacies of business and what it takes to be a leader in very competitive markets. In 2018, John and Cody saw an and entry point in the CBD industry and pounced on it. Opening several stores within months of the Farm Bill (December 22, 2018) being signed into law, their business acumen quickly earned them a strong position in the market. Instead of following other business models strictly dedicated to a pricing model, they decided that the focus of their CBD locations would be on educating the public, and raising the industry standards for quality control, third-party-lab-testing, and fair pricing on great products. Consequently, their staff is extremely knowledgeable about CBD strains and the potential health benefits that CBD and other cannabinoids may have. John’s and Cody’s commitment to running a transparent, ethical business has moved them to the forefront of the industry and is keeping them leaders in a fast-moving, ever-changing environment.

Create lets you turn English into full stack apps. It's an AI "text to app" builder for entrepreneurs. Our mission is to give everyone the power of software creation. Our ambitious first step is to power a new generation of entrepreneurs as their AI product engineer. We’re hiring for the early team (first 10) who want to create an iconic product and shape our culture. Our team is small and talent-dense. We’ve built products people love and look for people who care about building insanely great products. Our investors include Bessemer, Uncork and the founders of Shopify, Zapier, Turing, Docsend, Front, Intercom, Shippo, and more.

Spero helps practices offer virtual IOP (VIOP) to patients anywhere who are transitioning out of IP care, or who need more than OP care to prevent IP hospitalization. This increases access to care while lowering readmission rates. We focus on simplifying consultations and documentation for clinicians so they can focus on patient care, while also tracking patient progress through assessments and behavior reports to create a predictive care model. This helps inform clinicians when a patient is high risk, progress is regressing, individualizes treatment plans, and offers other insights. This data quantifies patient symptoms better than normal qualitative documentation. Spero helps clinics improve patient care and quantify treatment outcomes to allow clinics to negotiate VBC contracts with insurance, which increase clinic revenue and lowers costs for insurance. VBC means higher quality care, in-network coverage for patients (lower out of pocket costs), and decreased readmission rates.

Anon is the Integration Platform for the Internet. Empowering developers to build user-permissioned integrations for sites without APIs.

Trustible AI is an early-stage DC based Software-as-a-Service startup that is on a mission to enable organizations to adopt Trustworthy and Responsible AI (RAI) practices. Our platform helps companies set internal RAI policies, establish a single source of truth for AI use cases, conduct internal AI audits, create public transparency pages and comply with an increasing number of AI regulations. We seek to empower customers to develop Responsible AI, define internal policies and perform external algorithm audits. We believe AI has the power to help the world, but only if it's developed and deployed with ethical considerations in mind. We think good AI governance helps build better AI and should be a critical component of any enterprise AI strategy.

Our mission is to connect people with purpose by providing a platform for jobseekers and volunteers to find meaningful work that aligns with their values. We believe that everyone has something to offer, and that by working together– no matter where we are located– we can make a difference in the world. We are committed to providing a user-friendly platform that makes it easy for people to find work that makes a social impact from home– whether that's in big cities or remote regions of the planet. We are committed to providing opportunities for people of all backgrounds and skill levels to find their calling via one-time actions like petitions and fundraisers, volunteer roles, and paid positions with nonprofits, advocacy organizations, political campaigns and action committees, social impact startups and enterprise, and within all levels of government. We also offer a variety of resources, services, and tools to help individuals find the right fit within the social sector. We believe that cause-driven work is a key way to contribute to society. We are excited to do our part to help promote social good via aligned careers and expand social impact around the world. Visit us at Remotelygood.us.

About GrowthX AI At GrowthX, we've redefined what AI-powered growth means for modern marketing teams. Since launching in 2024, we've grown from concept to eight-figure annual revenue. To date, we've raised a $12M Series A led by Madrona Venture Group and we partner with 50+ companies ranging from high-growth startups to industry leaders like Surge AI, Loveable, Webflow, Ramp, Superhuman, Strapi, Abnormal Security, and Homebase. We've built something different—what we call "service-as-software." Instead of handing you tools and leaving you to figure them out, we deliver complete outcomes. Our platform combines sophisticated AI workflows with expert human oversight to create, distribute, and optimize content that drives real business results. Our philosophy is simple: AI should serve experts, not replace them. We're not just building software. We're building the growth infrastructure that marketing teams wish they'd always had.