Top Mental Health Startups in 2027

Lyra is transforming mental health care through technology with a human touch to help people feel emotionally healthy at work and at home. We work with industry leaders, such as Morgan Stanley, Uber, Amgen, and other Fortune 500 companies, to improve access to effective, high-quality mental health care for their employees and their families. With our innovative digital care platform and global provider network, 10 million people can receive the best care and feel better, faster. Founded by David Ebersman, former CFO of Facebook and Genentech, Lyra has raised more than $900 million. Our roles can be full-time in our Burlingame, CA headquarters, OR virtual (remote candidates must be based in the United States).

Workit Health picks up where inpatient and outpatient addiction treatment leaves off. The Workit mobile platform, our flagship product, is a “recovery in your pocket” sobriety maintenance solution. We provide users with twenty-four hour access to written and audio driven therapeutic tools, an adaptive learning component, and a social environment for recovery support. The Workit platform makes recovering addicts and alcoholics' lives better by enabling them to immediately access help wherever and whenever they need it.

Big Health’s mission is to help millions back to good mental health by providing safe and effective non-drug alternatives for the most common mental health conditions including insomnia and anxiety. Designed by leading clinical experts, Big Health’s digital therapeutics expand access to gold standard care, including behavioral medicine, and are backed by industry-leading research and randomized controlled trials. By seamlessly integrating across the care pathway, from member engagement to billing via pharmacy benefit managers, Big Health simplifies adoption for both payers and patients, providing an inclusive, scalable, and affordable approach without serious side effects. Please note that Big Health will never contact job candidates via text message or any other messaging platform including Telegram. All official correspondence will occur through email. If you have concerns please reach out to [email protected].

Aura, “*Spotify for mental wellness,”* is the all-in-one app for mental wellness & sleep that provides the world’s most extensive mental wellness content library & community. Over 8 million people choose Aura to find peace, and Aura has won “Best of Apple”. By partnering with hundreds of top coaches & therapists worldwide as creators, Aura offers the world’s largest premium collection of meditations, stories, sleep tracks, life coaching, cognitive behavioral therapy, breathwork, hypnosis, prayer, and much more. Moreover, Aura is a community where coaches host free live sessions and even 1-1 coaching. Unlike traditional meditation apps that provide one-size-fits-all content libraries created by a few coaches, Aura leverages AI to provide anyone with personalized access to its all-in-one mental wellness library that continuously learns what works for you. Aura’s vision is to build the digital ecosystem for mental wellness and provide the power of healing to anyone, anywhere, anytime. Aura Health is a mission-driven, San Francisco-based start-up backed by world-class investors such as Cowboy Ventures, Reach Capital, 1517 Fund, and UC Berkeley SkyDeck, and executives of Spotify, Apple, Meta, and Youtube, just to name a few.

The world doesn't need another company just because. We promised only to build tapouts if we could figure out a way to impact society for the better. By 2025, tapouts will prepare one million children to take on our future challenges by transforming stress into success. tapouts is a science-backed program that was developed by educators and scientists to create a fun and safe space that enables children, ages 4-16 years, to learn lessons that last a lifetime. tapouts’ experienced and caring certified coaches help kids learn to express feelings, improve self-control, build confidence, and make friends around the world on their online platform. The weekly live virtual group sessions are 30 minutes and filled with games (and prizes!) with an approach combining best practices across interdisciplinary fields such as psychology, neuroscience, and education

We’re in the middle of a behavioral health crisis that we can’t ignore—especially not when it comes to our children. 1 in every 5 children has a behavioral health condition, yet up to 80% still get little or no help. Far too many families face insurmountable barriers when their child really needs help, and parents are too often left feeling alone and without the support they need. We can do so much better. That’s why we’re here!  When you join Brightline, you’re joining a team that has an unstoppable drive to change the lives of families across the country. We’re a team of thoughtful problem-solvers, expert and kind clinicians, and experienced operators and technologists. Above all, we’re committed to helping each other succeed, learn, and grow—all while bringing care to families when, where, and how they need it. No matter what you’re looking for in your next role, we’re pretty confident that you’ll #FindItAtBrightline.

Our vision at Tava is to make meaningful connection between mental health providers and clients accessible and easy.

Osmind is the platform for clinicians and researchers advancing new life-saving mental health treatments. Today, mental health disorders are one of the leading causes of death worldwide, especially among young adults, and are tied to shortening lifespans. While there have been developments in new psychiatric medications since the first FDA approval in 1954, today there is a growing movement among clinicians, patients, and researchers who are recognizing the need to accelerate new science. The Osmind treatment platform is currently used by leading interventional mental health practices to safely administer, monitor, and analyze the use of TMS, ECT, ketamine, SPRAVATO®, and psychedelic medicine for people living with moderate to severe mental health conditions. The core EHR technology is precisely developed for interventional treatment workflows and designed to support a strong therapeutic alliance, including journaling tools and assistance with health plan reimbursement, which is a significant access hurdle for millions of patients. Research from our platform is already helping to set new standards for mental health interventions. In the largest published real-world analysis of ketamine infusion therapy (KIT), we teamed up with Stanford University School of Medicine to share findings in the Journal of Affective Disorders (March 2022). Osmind is a San Francisco–based public benefit corporation led by scientists, technologists, and psychiatrists. We are backed by top investors DFJ Growth, General Catalyst, Future Ventures, Tiger Global, and Y Combinator. Come join us for an incredible amount of autonomy and ownership at a fast-growing startup working on one of the world's biggest problems.

Bearable makes mental and physical health tracking convenient and accessible to all, removing the need to juggle multiple different apps to stay on top of one's health and helping people to spot unique health patterns.

Headspace is your lifelong guide to better mental health. We make mental health support accessible to everyone, no matter their background or experience. Through our flagship Headspace app, we provide mindfulness tools for everyday life, including meditations, sleepcasts, mindful movement and focus exercises. Our enterprise offerings combine this experience with a human-centered model of care, with coaching, therapy, psychiatry and EAP services under one roof. Our team of experts ranges from mental health clinicians, to Emmy award-winning producers and data scientists, working together as one to help millions of people around the world be healthier and more productive. To learn more, please visit headspace.com.