Top Software Startups in 2026

Our startup is developing a software system to replace the current, outmoded paper-based data collection process used by clinical research investigators. This solution could save 25% of trial costs, accelerate time to market by 6-8 weeks, and drastically improve protocol compliance and data integrity.

The LiquidPiston 'X' engine is an advanced rotary internal combustion engine that is fuel efficient, extremely compact and lightweight, durable, quiet, and has near-zero vibration. The X-Mini engine is a 70cc gasoline SI engine, the size of a grapefruit, rated at 3-5 HP, weighing only 4 lbs. This engine is the company's most mature technology demonstrator - achieving 50% better fuel economy than comparable displacement piston engines. This engine can be used in generators, chainsaws, mopeds, UAVs, etc. In 2015 the company completed a $1M DARPA Feasibility study, and the company expects up to $12.5M in DoD contracts to develop diesel versions of its X engine for generator and UAV applications in 2016. The "X4" concept is a 30kW Diesel engine achieving 50% better fuel economy than a piston engine, in a 10x8x8" package, weighing 25lbs. While developed initially for the DoD, this engine will have applications including as a range-extending power source to increase range of an EV.

OpenTeams connects open source developers and projects with organizations that use that code in everyday life. Currently, 96 percent of proprietary apps contain open source components, which creates a management and maintenance time bomb. Open Teams fixes this problem by making it easy for organizations to connect and transact with the people that write and lead open source projects. Open source contributors showcase their contributions, get recognition and compensation for their work; organizations find and fund open source projects they depend on.

UpCloud sells hourly priced cloud computing resources from its data centres around the world. Customers can freely configure and scale their servers, run them when needed and pay for services that they only utilise. We have also developed a storage backend called MaxIOPS that offers the performance of up to 5 SSDs. We have capped the performance to 100 000 IOPS per storage device. Each VM can have up to four storage devices and thus enjoy performance of up to 400 000 IOPS and 4GB/s throughput.

ESP Inspire is your one-stop-shop for your entire needs relating to Web Design, Website Redesign, Web Development, E-Commerce, Website Maintenance, and Hosting. So far, ESP has designed and developed more than 600 websites In addition, ESP Inspire also provides complete Internet marketing solutions that include Search Engine Optimization, Pay-Per-Click Advertising, Social Media Optimization, and more. To-date, ESP has successfully optimized more than 1,000 websites bringing our clients targeted and steady traffic enabling them to enjoy a better ROAS (Return On Advertising Spend). ESP is driven by the idea of providing cost-effective solutions to our customers.

TimeDoc Health is empowering physicians to address one of the biggest problems in healthcare. Over the next 12 years, the number of chronically-ill Medicare patients is expected to nearly double, pushing Medicare into bankruptcy. TimeDoc Health is the leading Virtual Care Management solutions and services provider that enables providers to receive reimbursement, optimize VBC performance, and deliver better care through Medicare programs like Chronic Care Management (CCM), Remote Patient Monitoring (RPM), and Behavioral Health Integration (BHI). By combining advanced technology and a clinical nursing staff, TimeDoc augments existing client resources allowing them to reach an entire panel of patients on a monthly basis to close gaps in care, reduce costs, and deliver better clinical and financial outcomes.

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Open Road Integrated Media is a content marketing company that places the e-book in the center of a multi-platform universe, which includes film, video and other forms of digital entertainment.

Billion Dollar Boy in an influencer marketing agency setting a new standard for social communication. We are a team of doers who believe in the power of connectivity to meet the limitless demands of a digital audience. Combining creativity and collaboration with innovative technology, we produce better content through bright ideas and thoughtful solutions.

Zynq makes company offices smart with an all-in-one workspace management platform that redefines the relationship between people x space x time. Companies using Zynq can fully embrace the Hybrid Office, giving employees a quick way to find the best time and space to collaborate, meet with guests, and much more. Founded by ex-Googlers, we're backed by some of Silicon Valley's leading investors and our customers include top brands across many industries (like the LA Dodgers, Giorgio Armani, Estée Lauder and many more).