Top Medical Devices Startups in 2026

Element Science is currently focused on developing a device to protect vulnerable populations experiencing temporary periods of elevated risk for sudden cardiac death, successfully and cost-effectively while delivering an outstanding patient experience. By leveraging significant advances in technology and materials, it is creating a novel therapeutic wearable that will allow many more patients at risk of sudden cardiac death globally to receive a potentially life-saving therapy.

At ACTO, we’re on a mission to disrupt how drugs and devices are commercialized in the US and around the world. ACTO is the only one-stop-shop sales, marketing and training platform uniquely designed for life sciences to help increase sales and brand awareness while reducing compliance risks. We help pharma, medical device and dental companies increase rep effectiveness, message consistency and build a culture of continuous learning while helping them stay compliant.

We are are a startup in Sunnyvale. Our mission is to help and enable people to manage their Diabetes and Hypertension in all aspects of their daily life. We utilize our award winning hardware and software alongside a readily available care team. We focus on the wholistic care of patients inside and outside of the Doctor’s clinic. We connect with patients in the Doctors clinic, helping them get familiar with the program and vitals measurement devices and continue that relationship beyond the appointment. We provide a connection with our care team to provide timely health related answers, as well as, food and vitals measurement reviews to help our patients make lifestyle adjustments that are specific to them. As we continue to empower and support our patients, they have shown great strides in improving their overall health!

Cellular Vehicles is founded by two medtech engineers coming from Auris Health, a recent $3.4B J&J acquisition. They're working on optimizing "last-meter" delivery for cell therapies, which is becoming a huge unmet need as the CT field transitions from systemic to targeted administration of cells. Since company formation around 6 months ago, the team has conducted needs finding and concept development work towards iterations of their product, and they recently conducted a human cell study that backs the promise of their technology. Their vision is to offer the hardware infrastructure required to accelerate the transition towards localized cell-based therapeutics.

Levisonics Inc. is a technology company focused on the commercialization of a proprietary acoustic tweezing platform technology with applications in blood coagulation analysis, pharmaceutical drug development and testing, and fluid rheological measurement.

Our product is an eQMS specific for the medical device world. We specifically focus on quality not compliance and this is integrated into everything we do. This mindset allows us to help our customers be more effective and efficient at what they do best.

Biomeme's platform transforms your smartphone into a mobile lab for advanced DNA diagnostics and real-time disease surveillance. The system includes a docking station for real-time PCR, a mobile app to control the system and analyze results, and targeted test kits for preparing samples and identifying pathogens or diseases by their specific DNA or RNA signatures. The cutting edge platform performs to the gold standard used by the world's most advanced central labs but requires no lab equipment or special experience to use. The low-cost, user-friendly system enables mobile testing at the point-of-need for health care (mobile clinics, disease tracking, home use), agriculture (plant disease tracking, food safety), vector surveillance (Malaria, West Nile, Lyme disease), veterinary medicine, environmental monitoring (soil and water safety), and even education and citizen science.

The LUM System was designed by leading engineers and scientists in partnership with surgeons from academic and medical centers as an integrated system with three unified components: drug, device and decision software to guide cancer surgeons in the detection and removal of cancer cells in real-time during surgery. The LUM System includes three integrated components: a fluorescent optical contrast agent that is cancer- and immuno-activated, a novel hand-held imaging device that instantly scans the cavity walls to view the fluorescent cells with single-cell detection, and proprietary decision software that displays the image instantly on a monitor to guide surgical removal of cancerous tissue.

Our patented communication device, the Live1, provides seniors and those who care for them the ability to video chat, call, set appointment and medication reminders, detect falls, and receive direct access to aides 24 hours, 7 days a week. LiveCare greatly reduces the readmission rates of patients, increases the efficiency of home care facilities and nursing homes, and reduces unnecessary costs and ambulance rides. Families also love the peace of mind knowing their loved ones are safe, and have an easy way to connect with them via their personalized Family App.

Tidepool is a 501(c)(3) nonprofit organization with the mission of making diabetes data more accessible, actionable, and meaningful by liberating data from diabetes devices, supporting researchers, and providing great, free software to the entire diabetes community, including people living with diabetes and their healthcare providers. Tidepool Loop is a project to build and support an FDA-regulated version of Loop, to be available in the iOS App Store, intended to work with commercially available insulin pumps and CGMs.