Top Information Technology Startups in 2026

Develo is redefining the pediatric care experience by bringing its leading pediatric operating system and revenue cycle management (RCM) services to independent pediatric practices across the country. We've built a modern platform that pediatricians, patients, and parents all love with functionality extending far beyond traditional electronic medical record (EMR) system capabilities.

Your Founding Team, On Demand. Better partners with founders and enterprises to take products from 0 → 1 — and from build → market. We combine engineering and distribution so companies don’t just ship software, but ship products that can be adopted, sold, and scaled. The same team stays across product and growth, reducing resets between building and acquiring customers. We operate two focused practices: Better Software — a 0→1 engineering team designing and building robust web, mobile, and AI-native systems with long-term architecture in mind. btrsw.com Better Marketing — a marketing team helping early and growth-stage products gain traction through positioning, content, and acquisition systems. btrgrowth.com

SamCart is the first e-commerce platform, built from the ground up, for direct to consumer brands. Online shopping has changed. Today’s eCommerce runs on selling products, not brands. By focusing on the product level, and not the store level our customers can create beautiful sites that showcase their products, convert visitors into customers, and increase the value of each purchase. SamCart's mission is to empower entrepreneurs and brands with the tools they need to succeed. With our easy to use eCommerce platform and superior customer support, we have helped tens of thousands of businesses sell billions of dollars worth of products.

T-Rex has been recognized as a “fastest growing company” on the Inc. 5000 list. We’re blazing new paths in federal government IT modernization and transformation with our deep technical expertise in Systems Integration and Development, Cloud Adoption and Infrastructure Optimization, Cybersecurity, Data Engineering and Analytics, and Mission Critical Services.

Mosaic is the AI-Powered Workforce Management software that's radically changing how companies are managed. We helps companies manage the skills of their workforce and uses AI to prevent burnout, empowering teams to do their best work while still having a life. Mosaic provides the tools needed to connect and manage a modern distributed workforce.

Xometry, backed by General Electric, Highland Capital Partners, and other venture investors, is a rapidly growing startup that is transforming American manufacturing. Our proprietary instant quoting technology and nationwide network of manufacturers provides an unparalleled on-demand manufacturing experience. Custom manufacturing is a $60 billion industry in the United States, and it is our mission to provide advanced manufacturing capabilities to customers of all sizes - from Fortune 500 companies and government agencies to small businesses and startups.

We eliminate tens of thousands in upfront data expenses, while giving you the instant flexibility to pick up real-time full exchange feeds or terabytes of historical data when you need it. Whether you're a Fortune 500 bank or a single-person startup, we scale with your budget and needs to deliver the same cutting edge performance and data integrity. For more info, visit databento.com

Zowasel leverages data science, nature-based solutions, and technology to improve smallholder farmers' productivity, sustainability, and profitability across the value chain. The company works with corporate organizations, from processors to manufacturers, breweries to FMCGs, financial institutions, DFIs, and agricultural research institutions, committed to sustainable agriculture and transforming agriculture from a carbon source to a carbon sink. Zowasel provides farmer cooperatives and agribusinesses with technology and alternative finance and guarantees markets across national, regional, and global markets needed to earn more for their crops. Founded 2014 in Lagos, Nigeria, Zowasel is on a mission to develop sustainable value chains across communities, people, and the planet. Visit zowasel.com to learn more.

MindCloud builds wrappers around SaaS APIs, enabling a common interface between them. We then build integration workflows using these wrappers, allowing our clients to sync data between systems and trigger between across multiple platforms. MindCloud is full service. We take care to understand our clients' requirements and deliver them start to finish. While we hand-code these integration workflows, MindCloud is concurrently building a next-generation low-code platform for building and maintaining integrations.

Making the “Best Ideas Win” is our mission. We believe that innovation has the power to make the world a better place, is too important to be left to chance, and that every individual deserves an opportunity to make the most of their ideas. Our software is used by the most innovative companies in the world. We have over 200 customers that use Brightidea to give people a voice in sharing their ideas at large organizations. The problem we’re solving is complex, creative, and exciting. Each of our products can function as a powerful stand-alone tool or utilized as part of a tightly-integrated system. Our suite provides the most mature solution available to support the entire end-to-end innovation process.