Top Health Care Information Technology Startups in 2026

Eko is a digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its suite of AI-powered digital tools. Its FDA-cleared technology is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect disease earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko is headquartered in Oakland, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. Eko exists to ensure all patients have access to early heart and lung disease detection that improves and extends their lives.

Maybe you’ve supported a friend or family member who’s dealing with cancer. Maybe you’ve battled it yourself. At Syapse, our mission is to enable healthcare providers to deliver the best care to every cancer patient through precision medicine and it's our personal connections to this mission that unites us Together, we're building a revolutionary suite of products that integrate complex oncology data and share insights across the cancer care ecosystem including cancer care centers and life science companies developing the next generation of cancer diagnostics and medicines. Join us in our exciting mission to scale precision medicine to reach every cancer patient on the planet. All while making a positive impact in the lives of people battling cancer, their families and the organizations committed to their care.

Healing Innovations is a medical technology company focused on improving care within the rehabilitation continuum. Our mission is to increase access to rehabilitation through the development and commercialization of market-leading robotic technology that helps people improve health, mobility, and independence. Healing Innovations offers advanced robotic technology, software, and services to care settings throughout the rehabilitation continuum. Healing Innovations was named the 2021 Tech Startup of the Year by the Nashville Technology Council.

At Birdie, we’re on a mission to reinvent care for older adults. Our work is more than building technology. It’s about empowering care providers and families to deliver better, more personalised support. We’re building advanced technology that makes a genuine difference to people’s lives. By bringing everything together, Birdie helps providers save time, reduce risk, and improve the quality of care. Our platform supports care providers with digital tools to manage care delivery, compliance, rostering, and family communication — all in one place. Families also benefit from peace of mind, with greater visibility into their loved one’s care. • Real-time health insights • Predictive analytics for early risk detection • Seamless digital record-keeping We’re solving complex problems in healthtech from data privacy to large-scale integrations - improving care outcomes every day. • 1000+ home care providers across UK and Europe • 117,000 older adults remaining safer and more independent at home • 73 million hours of care delivered in 2024

CitiusTech - A unicorn with $200M+ revenue is specialist provider of healthcare technology services and solutions to healthcare technology companies, providers, payers and life sciences organizations. With over 4,000 professionals worldwide, CitiusTech enables healthcare organizations to drive clinical value chain excellence, across integration & interoperability, data management (EDW, Big Data), performance management (BI / analytics), predictive analytics & data science, and digital engagement (mobile, IoT).CitiusTech helps customers accelerate innovation in healthcare through specialized solutions, healthcare technology platforms, proficiencies and accelerators. Armed with cutting-edge technology & expertise, world-class service quality and a global resource base, CitiusTech consistently delivers best-in-class solutions along with an unmatched cost advantage to healthcare organizations worldwide. CitiusTech recently acquired FluidEdge Consulting (FluidEdge), a national healthcare management consulting company headquartered in Philadelphia, PA. FluidEdge has been ranked in the Inc 5000 as one of the fastest growing private companies in the United States. FluidEdge is now a wholly owned subsidiary of CitiusTech. CitiusTech has been recognized as a great place to work by the Great Place to Work Institute® for eight consecutive years (2012 to 2019). CitiusTech has also been listed in the 2018 Healthcare Informatics (HCI) 100, placing it among the top 100 healthcare technology companies in the US, for the third consecutive year. CitiusTech has also been closely associated with key industry organizations, such as HIMSS, HL7, CHIME Foundation, AHIP and ACHP.

Take Command is a software start-up on a mission to accelerate the adoption of a new health insurance model. We’re a small team doing big things in the healthcare industry.

AlayaCare is a provider of revolutionary cloud-based home healthcare software. With a product spanning Clinical Documentation, Back Office Functionality, Patient and Family Portals, Remote Patient Monitoring, Telehealth and Mobile Care Worker apps, AlayaCare offers a platform for homecare providers to achieve better outcomes for patients and payers. For more information, visit AlayaCare.com

Tempus is a technology company that has built an operating system to battle cancer. Tempus enables physicians to deliver personalized cancer care through its interactive analytical and machine learning platform. The company provides genomic sequencing services and analyzes molecular and therapeutic data to empower physicians to make real-time, data-driven decisions. Our goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as we gather more data.

We’re passionate about providing easier access to high quality healthcare. Do you want to help people get the healthcare they want — and get patients back to being happy? PlushCare is a San Francisco-based tech startup that makes it easy to find and meet with a doctor online, even in the same day. Our mission is to provide patients with the best doctors and the best medical experience in a friendly and personalized way. Our technology platform enables over 100,000 patients (and growing) get care from a board certified doctor online. With a NPS of 90, and an App Store rating of 4.9, we strive to provide the healthcare experience that patients deserve. We’re growing rapidly and looking for people to join our passionate team..

CircleLink Health is revolutionizing chronic condition healthcare by integrating AI-powered solutions with compassionate human care. Our AI clinical agents and tele-nurses (health coaches) engage chronically ill patients between Dr. visits to help them thrive. We’re a post Series A company growing fast by driving better patient outcomes and seamless doctor reimbursements at hospital systems like Northwell Health and dozens of clinics nationwide. Investors include Vivek Garipalli (Flatiron Health founding board member, Clover Health Founder/CEO), Fresco Capital, NVP Capital, I2BF and Blue Cross/Blue Shield.