Top Tech Startups in United States in 2027

We’re on a mission to make every human superintelligent. Our first product is a personalized AI like Jarvis in your pocket powered by everything you see and hear, that learns with you, remembers your entire life, and helps proactively before you even ask.

Jona is a technology company using AI to reveal the relationship between the microbiome and personal health. Our AI can input a person’s microbiome composition and, by having the AI read the entirety of the scientific and clinical literature, both interpret the health implications of the person’s microbiome and also provide guidance on the foods, lifestyle modifications and medications that can improve their microbiome and health, while providing fully sourced corresponding scientific evidence. We believe that rapid advances in microbiome science, use of generative AI to interpret complex testing and changes to the consumer health landscape have created a new opportunity to serve the 60-70 million Americans suffering from digestive problems. Although we are starting with digestive health, our combination of deep microbiome sequencing, large language models (AI) and repeated engagement with individuals enables us to quickly expand to address challenges in autoimmune conditions, obesity, mental health, Parkinson's, liver disease and more. Jona is an early stage company founded by Leo Grady, CEO in Residence at Breyer Capital, who is internationally recognized for his work to deliver AI in healthcare for nearly 20 years at pioneering bay area startups (HeartFlow), multinational medical companies (Siemens) and, most recently, as CEO of Paige.ai in New York.

Pave helps consumer and SMB credit risk teams increase approvals through AI-powered cashflow analytics. 100 million+ US consumers and businesses are financially underserved, simply because their data is not recognized by the traditional financial system. We solve this by transforming transaction data, loan performance outcomes, and credit reports into Cashflow-driven Attributes and Scores, enabling increased financial access to new customer segments without increasing risk. Our mission is to build a future where every person and business has access to equitable credit solutions by creating a new standard of Cashflow-driven Analytics. We’re growing quickly and would love to hear from you! [email protected]

MavenAGI is on a mission to reimagine enterprise customer experience, starting with support. We believe that today’s support experience is broken: slow and painful for customers, and expensive and human capital intensive for companies. We are building Maven to deliver better, cheaper support, for both end users and agents. With recent advancements in Generative AI, it is now possible to deliver delightful customer experiences at a fraction of today’s cost.

RDI is an overnight success — years in the making. We’re scaling fast (grew 4× last year), fueled by enterprise engagements with the top IVD manufacturers in the world. For a small team, we punch way above our weight. RDI has become the go-to CRO for large public diagnostics companies who rely on our creativity, tech-forward systems, and zero-excuses accountability to get trials done quickly and done right. We’re a fully integrated IVD CRO — a high-complexity CLIA lab, a technology-enabled CRO, and a national physician + lab network under one roof. This lets us run clinical trials with a level of speed and operational precision the industry isn’t used to. RDI was founded in 2008 and professionalized in 2017 through a search fund acquisition (not venture hype). We’re backed by long-term operators and growth investors — not dependent on VC burn or fundraising cycles. From 2022–2024, we expanded aggressively by doing the hard things right: building real infrastructure, earning trust from enterprise customers, and executing consistently. Our physician network was sourced from real insurance claims data and strengthened by CAP accreditation. No one has successfully started and scaled a modern CRO focused on diagnostics and medical devices in over 15 years. The industry is dominated by large, slow incumbents optimized for pharma — not speed, accountability, or precision. We’re the underdog — and we’re winning. Our goal is simple: prove our customers right, and prove the industry wrong. Get a feel for how we work: youtube.com/watch?v=3tccEbsWIl8

Conviva helps streaming businesses act within seconds of observation to grow their business ahead of the competition. Conviva’s leading global streaming analytics platform provides comprehensive, continuous, census-level measurement through real-time, server side sessionization at scale. Using just a single sensor and a single pipeline, its 60+ patent platform enables marketers, advertisers, tech ops, engineering and customer care teams to acquire, engage, monetize and retain their audiences. Conviva is dedicated to supporting brands like DAZN, Disney+, Hulu, Paramount+, Peacock, Sky, Sling TV, TED and WarnerMedia as they unlock the incredible opportunity in streaming media. Today the Conviva platform processes nearly 3 trillion streaming data events daily, supporting more than 500 million unique viewers watching 200 billion streams per year across 4 billion applications streaming on devices. To learn more, visit conviva.com. Conviva is headquartered in Silicon Valley, with offices in New York, London, Madrid, Bengaluru, Beijing and Singapore. Conviva is founded by professors from Carnegie Mellon and U.C. Berkeley and backed by NEA, Foundation Capital, and Time Warner Investments. To learn more, visit conviva.com.

Forma.ai is a Series A startup based in Toronto that’s reinventing sales intelligence for leading enterprise organizations. Forma.ai helps Fortune 500 companies automate and optimize sales compensation and critical sales operations functions. Our growth has been fueled by our passion for fundamentally changing and shaping how companies use sales intelligence to drive business strategy. We’re welcoming equally driven individuals who are excited about creating something big!

Visme is the world’s most versatile content creation tool, empowering individuals and leading brands to create and present compelling stories in the form of engaging presentations, infographics, documents, videos, graphics and everything in between.

When an operator stops at a Mudflap network truck/fuel stop, when there they open the Mudflap app and select the fuel stop where they want to fuel. One tap of a button will then ''generate a fuel code -- it's a numeric code unique to you and that particular truck stop,'' Desai said. That code is then what you show to the fuel desk clerk, and how they ID you as a Mudflap customer, turning on the pump for you. Then, essentially, you're done. Mudflap was established in 2016 by Sanjay Desai in Palo Alto, California.

KoiReader Technologies is a global MNC defining the future of Industrial AI. Founded by industry experts and powered by a strategic partnership with NVIDIA, we turn complex operational challenges into intelligent competitive advantages for our Fortune 500 clients. Through KoiVision®—our patented Digital Operations Platform and AI Operating Model—we are setting the global standard for how Generative AI and Computer Vision automate supply chain and logistics. Craft your own destiny. Join the leaders of the AI Revolution.