Top Tech Startups in North America in 2027

Alpaca Health enables clinicians to become entrepreneurs, starting in autism care. We help clinicians launch and scale their own clinics by providing AI-powered software, payer contracting, and full back-office infrastructure. Our goal is simple: shift power in healthcare away from large consolidated entities and back to clinicians. We've raised over $14M in funding from early-stage investors like Core Innovation Capital, Adverb Ventures, and South Park Commons, and are building for long-term category leadership. More importantly, we're serving hundreds of patients, while growing 30% MoM.

Alva is your Quantamental Investing AI Agent. Designed to supercharge your investment process, Alva automates the entire research workflow – from initial idea generation and deep data analytics to real-time trend monitoring, robust strategy formation, and thorough backtesting. Built collaboratively with the investment community, for the community, we empower you to build, share, and grow your investment edge together.

Enurgen builds DUET, a 3D physics-based software platform for utility-scale solar and battery storage. DUET simulates what a plant should produce at every timestep of a 30-year life, compares it against what the field actually did, and attributes the gap down to the individual component. Conventional monitoring can tell you a plant is underperforming — working out why is the hard part, and that's the problem we solve. Every megawatt-hour a solar plant fails to produce is one that comes from somewhere else. Recovering it needs no new land, no new panels, and no new interconnection queue — just a correct answer about what went wrong and where. The model came out of SUNLAB at the University of Ottawa, with more than a decade of research behind it. It runs across the asset lifecycle: - Design — terrain-aware 3D modelling to establish a realistic performance baseline before anything is built. - Construction — analysis from the moment equipment comes online, so issues surface before commercial operation rather than years into it. - Operations — minutely, string-level analysis with automated root-cause loss detection, separating recoverable losses from the ones that aren't and routing the fixable ones into the maintenance system. We're a small, early-stage team with an office in Ottawa, Ontario. The engineering work is heavy on data: analytical queries over fleet-scale time-series, streaming pipelines feeding live analytics, on-prem software that keeps running when the WAN doesn't, and dashboards that stay fast at that scale. Research sits at the same table as engineering, so the physics and the software get built against each other. Hybrid-first, with remote on the table for any role. Every role includes an equity grant. You don't need a solar background — the domain is interesting, our customers are sophisticated, and you'll pick it up.

There’s a massive transition happening in the video games industry right now. Gaming has become a full-blown cultural movement, and many fail to appreciate how it has already become the dominant form of leisure and entertainment for an entire generation. But as culture has evolved, technology has advanced, and more people have gravitated toward games, the industry incumbents that run the show haven’t kept up. Our big bet is that by empowering game creators with better technology, we'll make the entire ecosystem more welcoming, connected, efficient, creative, and fun for all. We’re an early stage startup backed by Thrive Capital, Griffin Gaming Partners, Ribbit Capital and a16z's inaugural SPEEDRUN class. Our mission is to help game creators achieve independence by building the tools they need to start, run, and scale their businesses.

Therapists hold the world together. They also run businesses, file insurance claims, write letters, fill forms, supervise new grads and do hours of paperwork every night. Practice management software has existed for decades. It records what therapists do. It can't actually do any of it. Klara is the AI at the heart of Klarify. She handles the work that comes after the session: clinical notes, treatment plans, clinical letters, insurance claims, between-session resources, supervision prep and finding new clients. More than 11,000 therapists use Klarify today. Privacy comes first: Klara never trains on therapists' notes or client data. Our mission is to empower therapists, not replace them, so they can focus on the one thing only a human can do: be present with their client. Klarify is backed by Y Combinator (Spring 2026) and has raised $1.7M. Moody (CEO) is a second-time founder who co-founded Circleback.ai and hosts the Future of Therapy Podcast. Bergie (CTO) built LLM infrastructure at Workday.

UpSunday is a brand, web, software and motion design studio based in San Diego, California, designing and building brands, websites, custom software, and motion and 3D for ambitious companies worldwide. We work as one small, senior team from first idea to launch: brand identity and strategy, websites that load fast and rank, custom software and products, and motion and 3D that make a brand feel alive. Everything is designed and built in house, so what you approve is what ships. We work with founders launching something new and established companies ready for their next chapter, in San Diego and around the world. Our work has been recognized by Awwwards and CSS Design Awards. Great work doesn't wait for Monday.

We’re building Reflow, a workforce and workflow intelligence platform that helps teams understand and improve how work gets done.