Top Mental Health Startups in California, US

We believe that mental health is just as important as physical health. We recognize that mental health issues can be complex and multifaceted, and we are dedicated to treating the whole person, not just the symptoms. We aim to create a world where mental health is no longer stigmatized or marginalized, but rather is embraced as an integral part of one's overall well-being. We believe that by providing quality care that is both evidence-based and compassionate, we can empower individuals to take charge of their mental health and achieve their full potential. We are passionate about making a positive impact on the lives of those struggling with mental health issues and we strive to be a force for positive change in the field of mental healthcare. Rula is a remote-first company. We currently hire in most U.S. states, with the exception of Hawaii.

Modern Health is a mental health benefits platform for employers. They are the only solution to cover the full spectrum of mental well-being needs through both evidence-based technology and professional support from a certified coach or therapist. Whether someone wants to proactively manage stress or treat depression, Modern Health guides people to the right care at the right time and helps companies save money in engagement and healthcare costs. Modern Health has raised over $11M from Kleiner Perkins and Y Combinator and works with top companies that want to take a proactive approach to mental well-being.

The world doesn't need another company just because. We promised only to build tapouts if we could figure out a way to impact society for the better. By 2025, tapouts will prepare one million children to take on our future challenges by transforming stress into success. tapouts is a science-backed program that was developed by educators and scientists to create a fun and safe space that enables children, ages 4-16 years, to learn lessons that last a lifetime. tapouts’ experienced and caring certified coaches help kids learn to express feelings, improve self-control, build confidence, and make friends around the world on their online platform. The weekly live virtual group sessions are 30 minutes and filled with games (and prizes!) with an approach combining best practices across interdisciplinary fields such as psychology, neuroscience, and education

At TalkDoc, we understand that having a mental illness is an extremely isolating experience, where most people don't even believe you suffer from a mental illness, or downplay what that might mean in your life. Patients who suffer from severe mental illness such as psychosis often go untreated until they hit the breaking point because of this. Talkdoc provides mental healthcare to patients on Medicaid, in more than 5 counties in California, through our professional corporation partnership. TalkDoc has established itself by having the best outcomes in the entire country for Medicaid. We see mental health hospital utilization rates of 0.16% per year, as compared to 3%-4% for the general Medicaid population who sees a mental health clinician. We've helped thousands of people live healthier and happier lives. We are moving from a family business to high-growth startup, and we started that three months ago. Our technology mission is to be the safest and most private form of healthcare, that keeps patient data private long-term, while still offering the most advanced technological solutions, such as AI clinical assistants in workflows.

We’re building a new kind of mental health system Industry-best clinical experiences, better client outcomes, groundbreaking innovation, and access to the highest quality care. This is how we’re raising the bar for the entire industry.

Kick Health helps smart, capable professionals overcome the fears that hold them back from being the very best versions of themselves. Our personalized telemedicine service offers easy access to sleep medicine and beta-blocker prescriptions, the insider's edge to blocking nervous symptoms like racing heartbeat, shaky hands, or trembly voice. Kick is partnered with leading experts from Stanford, Yale, and Harvard in psychiatry, medicine, and emotional fitness.

Vedicscan is an AI-powered astrology and spiritual wellness platform rooted in authentic Indian Vedic scriptures. We’re building an intelligent companion that combines astronomy data, rule-based astrology, and large-language-model reasoning to deliver personalized forecasts, compatibility checks, and actionable remedies. Our mission is to make astrology credible, transparent, and practical for the modern generation — moving it from superstition to a data-backed life-guidance tool. We’re currently developing our MVP and looking for a passionate technical cofounder who’s excited about blending machine learning, cultural heritage, and human-centered design into one seamless product.

We're building a relationships operating system for couples - a modern, AI-native platform to help couples gain understanding and coordinate their actions at scale. Our mission is to make relationship health as measurable and improvable as financial and physical health.

Today's healthcare plans & payers struggle with fragmented tools and inconsistent quality across their Behavioral & Mental Health services. Our end-to-end solution transforms network management by automating documentation review, monitoring quality metrics, and providing AI-powered decision support - all in one integrated platform. This comprehensive approach ensures consistent quality delivery across mental & behavioral health services while reducing administrative overhead.

We’re living in a time of polycrisis. Not one problem, but myriad entangled, global problems: climate collapse, social fragmentation, runaway technologies. The systems meant to sustain life are accelerating its breakdown. The old ways—isolation, extraction, and short-term gain—are collapsing under their own weight. They will not carry us forward. But something else is stirring. A deeper possibility. A different logic. Humanity needs to meet this moment, not with band-aid solutions, but with systemic transformation. We need innovation more than ever, but it must be life-aligned. For that, we need a radical shift in how we think, relate, and create. That's what the Flourishing Systems Foundation was designed to catalyze.