Top Mobile Health Startups in 2027

Eko is a digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its suite of AI-powered digital tools. Its FDA-cleared technology is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect disease earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko is headquartered in Oakland, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. Eko exists to ensure all patients have access to early heart and lung disease detection that improves and extends their lives.

Greenspace (greenspacehealth.com) is transforming mental health systems by improving the way that care is accessed, measured and delivered. Greenspace is a growth stage technology startup with offices in Toronto and Kelowna. Since launching in 2016, the platform has been deployed across thousands of mental health practices and organizations and expanding across Canada and the US. Mental illness has passed HIV/Aids, malaria and diabetes as the leading cause of disability in the world. While there is no cure, psychotherapy is the most cost and clinically effective form of treatment. Greenspace has developed solutions that draw on technology and clinical research to improve patient outcomes within this traditional psychotherapy model. Our Measurement Platform enables mental health providers and organizations to implement consistent evidence-based measurement into their practice. Our Intake Module facilitates a more effective referral into mental health and addictions services. Our Self-Guided Module is a population health solution that provides mental health support directly to individuals in various settings. We recently helped develop and launch Wellness Together Canada (ca.portal.gs) – a major initiative funded and launched by Health Canada to provide virtual mental health and substance use support for all Canadians through COVID-19.

Twin Health is a revolutionary Precision Health platform combining IoT Sensors, Machine Learning, and Medical Science to reverse chronic diseases like diabetes and improve human metabolic health. It was founded by experienced entrepreneurs with extensive experience building software platforms used by more than 100 million devices around the world. We are backed by Sequoia Capital, Iconiq Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena and Sofina with $183M in Series A, Series B, and Series C funding. At Twin, we have achieved groundbreaking medical results for chronic disease reversal (12 papers published in top medical journals) using our patent-pending Whole Body Digital Twin™ technology (5 patents filed), which analyzes complex biosignals from wearable sensors, predicts metabolic outcomes using ML, and recommends highly-personalized treatments based on the metabolic profile of each patient. Our interdisciplinary team consists of engineers, scientists, and medical doctors who collaborate closely to develop these technologies and deliver exceptional health outcomes. We launched our product in 2018 with an initial focus on diabetes; doctors and coaches use our IoT- and ML-based software platform to improve the health of diabetic patients every day.

Plume is a health tech company for the transgender community. The company focuses on radically increasing access to care, medication, and products for the trans community, supporting a bold, authentic and healthy lifestyle. Its vision is to make gender-affirming care available to anyone until it transforms healthcare for every trans life.

Lemonaid Health is a direct-to-consumer online healthcare company – we’re a technology company, an online doctor’s office and an online pharmacy. We exist to help Americans nationwide get the convenient and affordable primary care they need online. Our doctors, nurse practitioners, pharmacists and customer service team wow patients with an amazing 5* level of service every time. We’re building the most convenient and affordable healthcare experience in the US, which we believe will start as an online company. According to the Inc 5000, we’re the 25th fastest growing company in San Francisco! We’re an entrepreneurial team of over 100 people. We’re backed by large strategic investors and amazing healthcare investors like OTV and Health Velocity Capital. Take a look at the reviews on our website for what patients say about how we help them. We’re proud that we’re the highest rated online consumer healthcare app on the Apple App store. Our internal team culture is to try to wow others in the team as much as we WOW our patients.

THE PROMISE With ultrasound a doctor can see into the heart of someone in cardiac arrest or into the abdomen of a woman with an ectopic pregnancy, and save their lives. 75 years after its invention, ultrasound remains an indispensable tool for diagnosis and monitoring. THE PROBLEM 60% of the world lacks access to medical imaging because current technologies are unwieldy, expensive, and require extensive training. While doctors carry supercomputers in their pockets, they still rely on the 200-year old stethoscope​ as their primary diagnostic tool. THE SOLUTION Our mission is to democratize healthcare by making medical imaging accessible to everyone around the world. Butterfly Network has raised >$350M to develop and commercialize a handheld, smartphone-connected ultrasound probe powered by AI. We operate at the intersection of medicine, engineering, and machine learning to create breakthrough technology that becomes smarter with each new patient.

Salvo Health helps millions of Americans who face chronic health conditions through specialty medicine and innovative virtual-first clinics. Salvo Health members receive support with a coordinated care team, customized care plan, and async, on-app, communication through a direct-to-consumer subscription model, no insurance required. Salvo Health is backed by leading health care investors from innovators like Livongo, Ro, Ginger, Forward, Brightline, Tia, and others. Salvo Health care will draw on expertise from board-certified specialty physicians, registered dietitians, psychologists, and health coaches who will deliver wraparound support on a multi-month journey to better health. Salvo Health is the first to bring a scalable, tech-enabled “functional medicine” approach to chronic disorders. We go beyond masking symptoms to identifying the root causes for each person, so conditions can be managed.

At American Well, we believe digital care delivery will transform healthcare. Our mission is to connect and enable providers, insurers, patients, and innovators to deliver greater access to more affordable, higher quality care. We do this by partnering with our clients to deliver video visits over mobile and web. We have doctors, therapists, and specialists on staff to help people get care when and where they need it most.

CheckedUp is a point of care company that actively engages patients before, during and after visiting the medical practice. Our vision and trajectory is to be the premier specialty point of care company providing condition-specific, active patient engagement through a variety of digital touch points to help patients as they make critical decisions about their treatment. We help practices and doctors engage with their Patients to help improve health outcomes and elevate the patient experience.

Tombot makes robotic animals that transform the daily life of individuals, families and communities facing health adversities. Originally designed to meet the specific medical needs of seniors with dementia, Tombot Puppies have also been preordered for children with Autism, adults with high impact chronic pain, major depressive disorder, anxiety, bipolar disorder, and PTSD, and for long inpatient stays and arduous outpatient treatments at hospitals. Peer-reviewed studies show that robotic animals positively affect some users’ ability to cope with stress, anxiety, loneliness, depression and pain, reducing their need for psychotropic and opioid medications. Key Milestones and Metrics: • Completion of our 5th generation prototype and 3rd round of customers studies with 100s of seniors with dementia • Over 3,900 preorder and waitlist customers • Member of StartX: Stanford-funded startup accelerator program • Member of the Canadian Creative Destruction Lab accelerator program • Member of Children’s Hospital of Los Angeles accelerator program (CTIP) • Large-scale clinical trials in development with Children’s Hospital and the University of Southern California to demonstrate reduced stress, anxiety and pain for pediatric hospital inpatients • Large scale study in development with the LAC-USC Hospital Burn Unit to demonstrate reduced stress, anxiety, and pain for pediatric burn patients • Major national and international media coverage • Winner 2019 RoboBusiness Pitchfire competition • Filed multiple trademark, design and provisional utility patent applications • U.S. TAM: $9.0B (seniors with dementia plus mild cognitive impairment)