Top Material Science Startups in 2027

Enovix is a advanced silicon-anode lithium-ion battery development and production. The Company's proprietary 3D cell architecture increases energy density and maintains high cycle life. Enovix is building the first advanced silicon-anode lithium-ion battery production facility in the U.S. The Company's initial goal is to provide designers of category-leading mobile devices with a high-energy battery so they can create more innovative and effective portable products. Enovix is also developing its 3D cell technology and production process for the electric vehicle and energy storage markets to help enable widespread utilization of renewable energy.

unWOOD is a new category of material engineered to transform low-value plastic waste into a sustainable and durable wood alternative. It rescues plastic from landfills, saves mature trees from being cut down, and is fully recyclable at the end of its life. unWOOD outperforms traditional wood by being resistant to water, termites, weather, and heat. One metric ton of Plastic Waste Recycled makes 2MT of unWOOD (that’s 40 benches) and saves 3 fully matured trees.

Novyte is building production-grade materials informatics platforms that help R&D teams in chemistry, materials science, pharmaceuticals design and manufacturing to test and optimize materials faster using AI/ML. We combine intelligent automation, AI systems, and scientific computing to accelerate real-world experimental workflows. This is deep-tech product engineering — not a typical SaaS dashboard.

Amaratek provides specialized contract services to the U.S. Department of Defense and other government and commercial partners, with a focus on developing innovative technologies and practical solutions to complex technical challenges. Our work has included the development of biological systems for the neutralization of chemical warfare agents, including the successful delivery of a working system to the U.S. military. Our experience supporting defense-related programs has given our team a unique understanding of how to develop reliable technologies for demanding environments where performance, safety, and operational reliability are critical. We recognize that many of the capabilities and technical approaches developed for military applications can also provide significant value in civilian and humanitarian settings. Amaratek applies this experience to civil government and international projects where the need for resilient and dependable infrastructure often mirrors the challenges faced in defense environments. Areas such as public health, water treatment and management, energy systems, transportation, and environmental protection require many of the same principles of reliability, adaptability, and innovative problem-solving. In addition to our work with U.S. government agencies, Amaratek provides technical services and expertise to foreign governments, nongovernmental organizations (NGOs), and social entrepreneurs. We work collaboratively with our partners to understand their specific challenges and develop practical, sustainable solutions that can be implemented in real-world environments. Our goal is to take the technical expertise and problem-solving capabilities developed through demanding defense and government projects and apply them more broadly to challenges that improve the resilience, safety, and quality of life of communities around the world.

Asgard Aerospace is building a coordinated industrial network that expands U.S. aerospace and defense manufacturing capacity. The company operates an advanced manufacturing and integration facility in Austin, Texas, and pairs this physical capability with Launchbelt, a secure digital platform that connects fragmented suppliers into a unified production ecosystem. Launchbelt provides a defense-aligned digital thread for travelers, traceability, QA, and compliance, with intelligent routing that evaluates capability, capacity, and performance across thousands of facilities. This creates predictable, high-reliability throughput for space, defense, aviation, UAS, and eVTOL programs. Asgard’s Command Forge facility serves as the anchor node of the network. It delivers composites, machining, harnessing, and integrated assembly with AS9100D and ITAR/CUI infrastructure, and it validates Launchbelt workflows through live production cycles. Each Forge is a replicable model that strengthens national aerospace capacity and supports program-level certainty for government and commercial partners. Asgard establishes a new category in the industrial base: a defense-aligned manufacturing network that synchronizes the operations of many facilities through a combined physical and digital platform. The result is faster onboarding, reduced coordination friction, higher quality, and an industrial system built for modern aerospace scale.