Top Artificial Intelligence Startups in 2026

At Toi Labs, we’re pioneering the next frontier of personal health monitoring—starting in the most unexpected place: the bathroom. By transforming the toilet into a passive health companion, we deliver real-time, actionable insights into gut health and more—without requiring users to change their behavior. Our platform enables early detection and preventive care right from the home. Recognized by TIME as a Best Invention of the Year and backed by TOTO, Sloan and the NIH, we’re combining elegant design, embedded technology, and data science to redefine how—and where—healthcare happens.

nate is a venture-backed, intelligent automation, social shopping and payments startup, with offices in New York and London. nate just closed its series A round, raising 38MM from Renegade, Forerunner Ventures, Coatue and Canaan, among others. nate was created based on the principle of “humans inspire, machines execute”. It guides our team to create a product and company that is truly consumer and privacy first, and that will play a part in online shopping solutions from moment of inspiration to purchase.

Afresh is on a mission to reduce food waste and increase access to nutritious food globally by transforming the fresh food supply chain. Our AI-powered solutions optimize the multi-trillion-dollar grocery industry's food ordering, production, and merchandising processes. We built the first platform capable of handling all of Fresh food’s complexities. We are relentlessly focused on helping grocers reduce waste, increase profitability, and bring better, fresher food to their communities. Afresh is currently deployed in hundreds of grocery stores across the United States and is on track to reduce 30 million pounds of food waste per year with our existing customers alone. By 2021, we're aiming to reduce food waste by a quarter billion pounds per year. We are a passionate team united by our mission to make an impact. As an Afresh employee, you’ll own meaningful work that will challenge you and change the future of how fresh, nutritious food makes its way through the supply chain. We hope you’ll join us!

Leucine is multiplying on its mission to make global drug manufacturing compliant and audit-ready. Within a short period, we have signed up Fortune 500 companies as customers and raised funds from marquee VC investors. Hundreds of pharmaceutical manufacturing & quality teams globally use the Leucine no-code platform daily to improve drug quality, efficiency, and sustainability by orchestrating 300+ complex regulated workflows from material receipt to batch release. We are now looking to onboard ambitious individuals across engineering, product, design, customer success, and sales to scale the product.

TrueFoundry is an Enterprise Platform as a service that enables companies to build, ship and govern Agentic AI applications securely, at scale and with reliability through its AI Gateway and Agentic Deployment platform. Its AI Gateway encompasses a combination of - LLM Gateway, MCP Gateway and Agent Gateway - enabling enterprises to manage, observe, and govern access to all components of a Gen AI Application from a single control plane while ensuring proper FinOps controls. Its Agentic Deployment platform enables organizations to deploy models on GPUs using best practices, run and scale AI agents, and host MCP servers - all within the same Kubernetes-native platform. It supports on-premise, multi-cloud or Hybrid installation for both the AI Gateway and deployment environments, offers data residency and ensures enterprise-grade compliance with SOC 2, HIPAA, EU AI Act and ITAR standards. Leading Fortune 1000 companies like Resmed, Siemens Healthineers, Automation Anywhere, Zscaler, Nvidia and others trust TrueFoundry to accelerate innovation and deliver AI at scale, with 10Bn + requests per month processed via its AI Gateway and more than 1000+ clusters managed by its Agentic deployment platform. TrueFoundry’s vision is to become the Central control plane for running Agentic AI at scale within enterprises and empowering it with intelligence so that the multi-agent systems become a self-sustaining ecosystem driving unparalleled speed and innovation for businesses. To learn more about TrueFoundry, visit truefoundry.com.

FiscalNote is a technology-powered global software data and media company that uses powerful machine learning to provide clients with the right policy information and insights, and at the right time so that they can better navigate market risk and uncertainty and maximize new opportunities. As the premier hub of domestic and global information for more than 5,000 clients worldwide, FiscalNote’s tools, analysis, news, and award-winning journalism delivers context, clarity, and a competitive edge in a rapidly changing world. To learn more about FiscalNote and its family of brands visit fiscalnote.com. FiscalNote has raised more than $230 million from prominent investors such as S&P Global, The Economist Group, NEA, Mark Cuban, Jerry Yang, Steve Case, etc.

At Alloy, we work with consumer goods companies that make the products we eat, wear, and use every day. We’re tackling a real and complex problem for them—managing supply and demand in the face of constantly changing customer behavior, highly complex supply chain networks, 40-year-old data standards and labor-intensive manual processes. Alloy is fast-growing, profitable, and backed by leading investors with an expanding presence across the world. Our team hails from successful startups, leading tech companies and Fortune 100 enterprises. We believe deeply in fostering individual ownership, iterating to excellence, focusing on what matters, communicating openly & respectfully, and supporting one another.

Citylitics delivers predictive intelligence on local utility & public infrastructure markets The U.S. needs to invest $4.5 Trillion over the next 5 years to upgrade its infrastructure, including water, energy, public transit, roads, airports, and more. Citylitics is the only source of predictive intelligence on where, how, and why these infrastructure investments will be made. Our Data Engine transforms over a billion documents buried in 31,000+ cities & utilities data sources into high value intelligence for targeted business development. The largest infrastructure industry leaders rely on Citylitics for external datasets and intelligence reports Citylitics' vision is a world where data drives Trillions of dollars of societal infrastructure investment towards the most ideal social, economic, and environmental outcomes.

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

VideaHealth products help clinicians, health insurances and large providers to detect diseases more accurately and earlier than the dental clinicians. This can help dental practices to become more profitable, health insurances to automatically approve claims and overall, significantly increase patient health.