Top Tech Startups in United States in 2026

At Toi Labs, we’re pioneering the next frontier of personal health monitoring—starting in the most unexpected place: the bathroom. By transforming the toilet into a passive health companion, we deliver real-time, actionable insights into gut health and more—without requiring users to change their behavior. Our platform enables early detection and preventive care right from the home. Recognized by TIME as a Best Invention of the Year and backed by TOTO, Sloan and the NIH, we’re combining elegant design, embedded technology, and data science to redefine how—and where—healthcare happens.

About Us -Founded in 2017 by IIT Delhi alumni, Attentive is a B2B vertical SaaS company serving the outdoor services industry in the United States. We are building an end to end SaaS platform with a deep-tech core that analyses geospatial imagery, enabling us to provide a suite of software solutions for our clientele.

MoodMe is an innovative B2B tech leader on a mission to revolutionize the way businesses engage and gain insights through AIaaS and enterprise agreements. By leveraging the power of Face AI technologies, we create experiences that are not just engaging but profoundly insightful, providing a window into the hearts and minds of the target audience. Our vision is to set the standard in empathetic engagement, where user-centric experiences boost customer satisfaction, foster loyalty, and drive outstanding performance across diverse industries. At our core, we are dedicated to uniting innovation and ethics to craft an AI landscape that is unbiased and empathetic, ultimately making a powerful positive impact on a global scale. And this is only the beginning!

Localcoin is a financial technology company that operates the largest cryptocurrency ATM network in Canada. Our network allows users to buy and sell Bitcoin, Litecoin, and Ethereum at over 400 retail locations across North America in more than 9 provinces and 3 states. Founded in 2017, Localcoin empowers consumers to join the cryptoeconomy by offering a simple cryptocurrency buying/selling experience to over 40,000 customers. Our partners include independent retailers and franchises such as Hasty Market and Gateway Newstands. We are a profitable cryptocurrency startup and we are growing at an exponential rate with over 50 new locations opened monthly. Localcoin’s mission is to bring cryptocurrency to your community, one ATM at a time. Learn more at localcoinatm.com.

TrueFoundry is an Enterprise Platform as a service that enables companies to build, ship and govern Agentic AI applications securely, at scale and with reliability through its AI Gateway and Agentic Deployment platform. Its AI Gateway encompasses a combination of - LLM Gateway, MCP Gateway and Agent Gateway - enabling enterprises to manage, observe, and govern access to all components of a Gen AI Application from a single control plane while ensuring proper FinOps controls. Its Agentic Deployment platform enables organizations to deploy models on GPUs using best practices, run and scale AI agents, and host MCP servers - all within the same Kubernetes-native platform. It supports on-premise, multi-cloud or Hybrid installation for both the AI Gateway and deployment environments, offers data residency and ensures enterprise-grade compliance with SOC 2, HIPAA, EU AI Act and ITAR standards. Leading Fortune 1000 companies like Resmed, Siemens Healthineers, Automation Anywhere, Zscaler, Nvidia and others trust TrueFoundry to accelerate innovation and deliver AI at scale, with 10Bn + requests per month processed via its AI Gateway and more than 1000+ clusters managed by its Agentic deployment platform. TrueFoundry’s vision is to become the Central control plane for running Agentic AI at scale within enterprises and empowering it with intelligence so that the multi-agent systems become a self-sustaining ecosystem driving unparalleled speed and innovation for businesses. To learn more about TrueFoundry, visit truefoundry.com.

At US Mobile, we’re on a mission to revolutionize connectivity. We're building a next-generation connectivity platform to connect the next billion wireless devices onto nationwide 4G and 5G networks, including your phone, drone, car, watch, pet tracker, and everything in between. We’re accomplishing this by leveraging cutting-edge technology and forward-thinking UI design. Whether it’s with our free high-speed international roaming, customizable perks, AI-facilitated plan savings, customizable plans, or real-time dashboards, we’re building the industry’s most delightful user experience all backed by our excellent customer service. We’re a rapidly-growing and innovative start-up with incredible and sustainable growth. We ranked 94th on Inc. 5000's list of private companies in the US in 2019, and we were recently featured this year by Forbes as one of America's top startup employers.

At January, we bring humanity to consumer finance. Using data intelligence, we create trust and deliver better outcomes for consumers and creditors alike. Our mission is simple: expand access to credit while empowering consumers to achieve lasting stability and control of their financial lives. We began by building the foundation for creditors to engage with and support their borrowers at scale across the entire debt lifecycle. We’ve mastered outsourced collections by combining best-in-class performance with differentiated consumer satisfaction and superior compliance.  And we’re just getting started. Together, we’re creating a financial system where trust and opportunity spark lasting change in people’s lives.

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

Speechmatics are global experts in deep learning and speech recognition, providing technology that understands every voice. We have built the most accurate and inclusive speech-to-text engine available, which is now working with an amazing mix of global companies. We are VC backed, in the final stages of growth fundraising. Joining us means working with some of the smartest minds around the world, focused on cutting-edge projects and deploying the latest techniques to disrupt the market. We believe in putting people first; we’ll do all we can to help you develop your skills and give you the tools you need to thrive. We support people to work wherever they work best and also understand the importance of coming together to collaborate, socialise and build relationships. This is only the beginning; we’re looking for amazing people like you to continue our journey…

NightUp is a cutting-edge nightlife reservation platform that lets customers seamlessly book tables and tickets to nightclubs, lounges, and events across the United States. By eliminating the need for direct contact with venues and promoters, NightUp modernizes the outdated booking process with a streamlined mobile experience, making reservations faster and more convenient. In 2025, the U.S. bars and nightclubs industry was valued at approximately $39 billion. With constant promotions, evolving venues, and emerging hotspots, staying informed can be overwhelming. NightUp bridges the gap between users and venues, fostering a more connected nightlife community. With thousands of nightclubs across the country, the potential for expansion is limitless.