Top Tech Startups in South Carolina, US in 2027

Founded in 2013, DoorDash is a San Francisco-based technology company passionate about transforming local businesses and dedicated to empowering new ways of working, earning, and living. Today, DoorDash connects customers with their favorite local and national businesses in more than 1,000 cities across the United States and Canada. By building intelligent, last-mile delivery technology for local cities, DoorDash aims to connect people with the things they care about — one dash at a time.

The Inside Sales Solutions approach builds on more than 20 years of experience selling and leading inside teams. We’ve seen what works and what doesn’t – and how each company needs its own formula for successful sales – and we put that expertise to work uncovering new opportunities for high-tech companies large and small. We are a premier inside sales agency with an entrepreneurial focus and a collaborative environment. We have a startup culture and influence global tech leaders - IBM, Oracle, HP, and McAfee to name a few.

T-Rex has been recognized as a “fastest growing company” on the Inc. 5000 list. We’re blazing new paths in federal government IT modernization and transformation with our deep technical expertise in Systems Integration and Development, Cloud Adoption and Infrastructure Optimization, Cybersecurity, Data Engineering and Analytics, and Mission Critical Services.

Chowbus is a food ordering platform which curates featured dishes from selected ethnic restaurants daily and delivers them fresh and hot to your home or office affordably with the tap of your cell phone. We provide dish-centric mobile ordering experience for consumers to easily explore and order authentic ethnic food and we empower local ethnic restaurants with the technology, tools, and marketing to grow their business.

Metabase is bringing data tools with the elegance and simplicity of consumer products to the crufty world of enterprise business intelligence. Our Open Source analytics and business intelligence application let installs in minutes, and can connect to most commonly used databases. It lets anyone in your company quickly ask questions, and create dashboards or nightly emails without knowing SQL. We provide an opinionated open source starting point for how companies should measure, analyze and share their data as well as a suite of tools to deal with the complexity that arises as they grow.

Pomelo Care is the national leader in evidence-based healthcare for women and children. We deliver personalized, high-quality clinical interventions from reproductive care and pregnancy, infant care and pediatrics, to hormonal health through perimenopause and menopause, with long-term preventive care and condition management. Our model delivers 24/7 multispecialty care to address the medical, behavioral, and social factors that most significantly impact outcomes for women and children. We partner with payers, employers, and providers to expand access to quality healthcare across the system. To search career opportunities or to learn more, head to pomelocare.com.

Created in 2009 by Yael Aflalo, we design and manufacture the majority of our limited-edition collections in our factory headquarters in downtown Los Angeles. All other garments are produced by responsible manufacturing partners here in the U.S. or abroad using sustainable methods and materials. We source sustainable fabrics and vintage garments while incorporating better practices throughout our supply chain to make beautiful styles at a fraction of the environmental impact of conventional fashion. It is our mission to lead and inspire a sustainable way to be fashionable.

THE PROMISE With ultrasound a doctor can see into the heart of someone in cardiac arrest or into the abdomen of a woman with an ectopic pregnancy, and save their lives. 75 years after its invention, ultrasound remains an indispensable tool for diagnosis and monitoring. THE PROBLEM 60% of the world lacks access to medical imaging because current technologies are unwieldy, expensive, and require extensive training. While doctors carry supercomputers in their pockets, they still rely on the 200-year old stethoscope​ as their primary diagnostic tool. THE SOLUTION Our mission is to democratize healthcare by making medical imaging accessible to everyone around the world. Butterfly Network has raised >$350M to develop and commercialize a handheld, smartphone-connected ultrasound probe powered by AI. We operate at the intersection of medicine, engineering, and machine learning to create breakthrough technology that becomes smarter with each new patient.

Machinio.com is one of the world’s largest platforms connecting buyers and sellers of inventory and related services across multiple industries. Founded in 2013 and acquired in 2018, Machinio now serves over 4,000 paying clients globally and continues to expand its reach and impact. Thousands of dealers and suppliers rely on the platform to market and sell their equipment, connecting them with millions of prospective buyers each year. Machinio is widely recognized for leveraging technology to simplify and modernize the buying and selling process. By introducing innovative tools and improving marketplace efficiency, the company has helped both buyers and sellers save significant time while facilitating high-value transactions worldwide. Machinio System is Machinio’s all-in-one software solution built specifically for dealers and service providers. Launched in 2018, it combines modern, fully customizable, SEO-optimized websites with a fully integrated CRM platform for dealers. This unified solution enables businesses to manage their entire workflow in one place — including inventory, lead management, quoting, invoicing, contact databases, email marketing campaigns, and more. With continuous feature development and a strong product roadmap, Machinio System empowers dealers and service providers to maintain a professional online presence, leverage intelligent sales and marketing tools, and consistently generate and nurture business opportunities. Machinio has been featured in leading media outlets including Forbes, Business Insider, Inc., EquipmentWorld, Agriculture.com, and others.

At TixTrack, we support our clients by creating superior ticketing solutions for performing arts and cultural institutions through a combination of modern technology, beautifully simple design, and the art of listening. Headquartered in the heart of the Broadway Theatre District, NYC, we are a small, but growing team of hardworking, highly motivated individuals. We are passionate about our work and driven to innovate with our customers to solve current and future challenges with new solutions. Our core product, Nliven, is a real-time platform that helps venues manage ticket sales efficiently while creating a more engaging buying experience for customers. With a presence across both the US and UK, we are anticipating robust growth in 2026. Even with a highly dispersed, largely remote workforce, we stay connected through our Slack channels, virtual events and regional meetups. Come see how we “role”.