Top Tech Startups in Chicago, IL in 2026

At Zerigo Health, we're changing what it means to live with a chronic skin condition. Millions of Americans with psoriasis and eczema face a broken system — months-long waits for care, treatments that don't stick, and costs that spiral out of control. We're fixing that. Zerigo's platform combines an FDA-cleared smart home device, AI-driven personalized care plans, and real human support to deliver clinical-grade dermatology care where people actually live — at home. Our results speak for themselves: 88% clinical success rates, 73% treatment adherence, and over $10M in savings generated for every 1,000 members on our platform. We're a fast-growing, mission-driven team at a pivotal moment. We are energized by hard problems, improving things along the way to benefit our members and each other. If you are motivated by meaningful work and the prospect of building something that genuinely improves people's lives, you'll fit right in here.

Stellar Creative is a Chicago-based advertising agency that understands one simple truth: People never remember what you say. They remember how you make them feel. We don’t just create ads—we craft experiences that tap into human nature and psychology, leaving a lasting impression. Backed by a dedicated research team, we dive deep into market trends and consumer behavior to develop strategies that truly resonate. Our expertise spans innovative marketing, emotionally compelling video production, web design, and TV commercials. We combine data-driven insights with creative excellence to not only capture attention but create meaningful connections. Because when a brand makes people feel something, that’s when it becomes unforgettable.

STEAMe is a workforce technology start up company turning fragmented systems into engines of economic advancement. Our roots in NowPow—a nationally recognized social care referral platform that connected 13 million people to vital care services—taught us how to deliver multi-sided platforms that power complex ecosystems. We channel that expertise into STEAMe, with purpose-built workforce solutions that close data and process gaps, connect stakeholders, and accelerate job placement and prosperity at scale.

We are Raider T Recruiting, a third-party driver recruiting agency built to help carriers connect with qualified CDL-A drivers across the country. Our team specializes in recruiting for local, regional, and OTR positions, including company driver, lease purchase, and owner-operator opportunities. We work across a wide range of freight types and operations, including dedicated, intermodal, truckload, dry van, reefer, flatbed, and specialized freight. With more than 60 years of combined recruiting experience and a nationwide network of recruiters, we understand what both carriers and drivers need from the hiring process. Our focus is on clear communication, accurate job information, strong driver matches, and helping carriers keep their trucks moving with qualified candidates. At Raider T Recruiting, we do more than generate interest. We help create connections between drivers and carriers that make sense for both sides.