Top Life Sciences Startups in 2027

Thirty Madison is a family of specialized healthcare brands devoted to creating exceptional outcomes for all. Each of its specialized brands is focused on a specific ongoing condition, and thoughtfully designed to support the unique needs of its community with personalized treatments and care; with Keeps for men's hair loss, Cove for migraine, Picnic for allergies, Facet for skin conditions, and NURX for sexual health. With empathy at the heart of its innovation, its proprietary care model empowers hundreds of thousands of people with ongoing conditions with the accessible, effective treatments across a lifetime of care.

More than 40% of all fresh produce is wasted in the US, which accounts for over $17 billion dollars in lost product annually and contributes more CO2 emissions than all of US transportation combined. Globally, food that is never consumed accounts for 7% of the global freshwater supply and 308MM hectares of land. Our goal is to reduce these drastic numbers by making the produce supply chain smarter. Strella uses proprietary IoT biosensors to monitor and predict produce quality in real time as it travels the supply chain. We reduce food waste and help deliver better quality produce to consumers. Our product is used commercially in high-value decision-making in apple and pear storage. We’re growing the team to improve our product and service higher impact markets.

At Sprinter Health, we’re tackling one of healthcare’s biggest challenges: reaching patients who have fallen through the cracks of our healthcare system. With a boots-on-the-ground clinician network and the tech platform to solve this problem at scale, we bring critical preventive care to folks who are otherwise not getting it, whether due to disability, socioeconomics, transportation insecurity, or simply not getting around to it. We believe that access to healthcare shouldn’t be so hard, and by making it easier for folks to get the diagnostics and preventive care they need, we can halt the growing tide of disease and healthcare costs in America. Since launching in 2021, we're now live across 15+ states, covering over 60% of the US population and partnering with 6 of the 10 largest U.S. health plans. We've served >60k patients in-home from ages 3 to 103. And with 5x revenue growth in 2023 and 6x growth in 2024, things are only accelerating. Our team of technologists, clinicians, and operators bring decades of experience from Google, Meta, Amazon, Epic, Aetna, and Oak St. Health. And with over $125M raised from top VC investors, including a16z, General Catalyst, GV, and Accel, we have everything we need to transform healthcare. Jobs at Sprinter Health We're looking for strong engineers and product managers at all levels who want to make an impact today. We want to change lives—save lives—and we could use all the help we can get. If you want to build things, we want to talk to you. If you want to grow faster than you ever could at a big company, we want to talk to you. If you want to make a difference, we want to talk to you.

At TalkDoc, we understand that having a mental illness is an extremely isolating experience, where most people don't even believe you suffer from a mental illness, or downplay what that might mean in your life. Patients who suffer from severe mental illness such as psychosis often go untreated until they hit the breaking point because of this. Talkdoc provides mental healthcare to patients on Medicaid, in more than 5 counties in California, through our professional corporation partnership. TalkDoc has established itself by having the best outcomes in the entire country for Medicaid. We see mental health hospital utilization rates of 0.16% per year, as compared to 3%-4% for the general Medicaid population who sees a mental health clinician. We've helped thousands of people live healthier and happier lives. We are moving from a family business to high-growth startup, and we started that three months ago. Our technology mission is to be the safest and most private form of healthcare, that keeps patient data private long-term, while still offering the most advanced technological solutions, such as AI clinical assistants in workflows.

Eli is a women's health company on a mission to improve lifelong health through continuous hormone monitoring. Hormones impact physical and mental health every day and at every stage of life. Eli offers real-time insights from hormones in saliva that can be tracked continuously over time, unlike traditional testing methods or send-out tests that only provide a single snapshot. With just three simple steps, Eli's at-home technology provides women with personalized hormone profiles to make informed decisions about their health. Eli is filling a data gap to transform how women manage their hormonal health in key areas like menopause, fertility, contraception, and endocrine conditions. Eli has raised a total of $9 million so women can have the information they need to optimize their overall health from puberty to beyond menopause.

Seed Health, Inc. is a microbial sciences company pioneering applications of bacteria to impact human and environmental health. In collaboration with leading academic partners, our foundry model accelerates breakthrough science to develop live biotherapeutics and consumer innovations. Our Scientific Advisory Board is comprised of leading scientists with expertise in microbiology, immunology, genetics, metabolomics, gastroenterology, pediatrics, environmental sciences, and women’s health. Learn more—seedhealth.com Our consumer portfolio, Seed®, develops next-generation probiotics for specific developmental stages and various ecosystems of the body—seed.com

AcuityMD is bringing transparency and efficiency to the medical device market by helping suppliers build stronger and compliant relationships with doctors and other healthcare providers. Our vertical-focused SaaS and data platform helps Medical Device sales, marketing, medical education, and product development teams collaborate around the multi-faceted relationships these companies have with the users of their products.

We provide the industry’s only direct-to-consumer healthcare test that analyzes microbial and human gene expressions (mRNA), with technology exclusively licensed from Los Alamos National Lab, in order to provide individuals with health insights and the nutrition they need. By joining Viome, you are joining a revolutionary movement. A movement that – for the first time in human history – will make becoming ill a matter of choice, and not simply bad luck. Scientists have worked for over a decade to develop this technology that offers unprecedented visibility into your body. With this, we can create a unique profile of the biochemistry and ecosystem inside of you, and make personalized, actionable, and adaptive recommendations for your health. Our at-home tests are not just one-time tests, but your true health companion, enabling you to monitor your health over time. Your results and recommendations adapt to your changing ecosystem so you are always aware and taking action towards maximizing your vitality and lifespan. The Viome team is made up of scientists, engineers, researchers and entrepreneurs who are passionate about radically improving the wellness of our customers.

Loyal is a consumer-focused dog longevity & genomics company. We help our furry friends live longer, healthier lives. Loyal was internally incubated by Celine Halioua while at The Longevity Fund. Celine was previously a Ph.D. candidate at Oxford in gene therapy economics and holds a BSc in Neuroscience.

Patient-matched orthodontic appliances designed from digital impressions may decrease treatment duration for patients and chair time for clinicians. SO will market this aesthetic medical device to orthodontists and their patients.