Top Enterprise Software Startups in 2026

Cockroach Labs is the creator of CockroachDB, the most highly evolved cloud-native, distributed SQL database on the planet. We help companies of all sizes — and the apps they develop — scale fast, survive anything, and thrive everywhere.

ABOUT ARTERA Our Mission: Make healthcare #1 in customer service. What We Deliver: Artera (formerly WELL Health®) is the patient communication platform that delivers happier staff, healthier patients, and more profitable organizations. We enable two-way conversations between patients and their healthcare teams through secure, multilingual messaging across multiple channels – including text, email, and telephone. By unifying disjointed touchpoints into a single, intuitive channel, Artera fuels connected patient experiences and empowers organizations to deliver the best customer service imaginable. Our Impact: Artera helps 500+ healthcare providers facilitate more than 1 billion messages for 40+ million patients annually. Our award-winning culture: In 2021, Artera was named #10 on the Forbes list of America’s Best Startup Employers, as well as being named one of Deloitte’s Fast 500 (#133). Artera was also recognized as one of the Best Midsize Companies to Work for in Los Angeles by Built In in 2022, and has been ranked on the Inc. 5000 list of fastest-growing private companies for three consecutive years. All of our open roles can be found at artera.io/careers

Hive is an email & SMS marketing CRM that helps brands sell more while keeping their customers happy and engaged. We make it easy for companies to segment and target their customers based on relevant attributes, automate email marketing campaigns, and send timely, high-converting emails. We started our company inside a University of Waterloo computer lab in early 2014, graduated from Y Combinator that summer (S14 batch) and have been growing ever since. Originally based out of Kitchener, our remote team of 14 is now distributed all across Canada!

Recorded Future arms security teams with threat intelligence powered by patented machine learning to lower risk. Our technology automatically collects and analyzes information from an unrivaled breadth of sources and provides invaluable context that’s delivered in real time and packaged for human analysis or instant integration with existing security technology.

Amperity is a stealth-mode enterprise software company founded by repeat entrepreneurs Kabir Shahani and Derek Slager. After a successful exit of their prior venture in 2013, the two are back at it again to address one of the largest unmet needs in the marketing technology space, and are building a powerhouse team to do so. Through the use of functional programming, modern big data tools, and a machine learning- powered data stitching platform, our team of talented engineers and trusted advisors are building a one-of-a-kind data-first application for marketing. Amperity is backed by some of the most notable names in tech -- including Madrona Venture Group, Liquid 2 Ventures, Hyde Park Ventures, and top executives and founders from multi-billion dollar companies like Concur, ExactTarget, Microsoft, and Isilon Systems.

Founded in 2013, DoorDash is a San Francisco-based technology company passionate about transforming local businesses and dedicated to empowering new ways of working, earning, and living. Today, DoorDash connects customers with their favorite local and national businesses in more than 1,000 cities across the United States and Canada. By building intelligent, last-mile delivery technology for local cities, DoorDash aims to connect people with the things they care about — one dash at a time.

Acquia empowers enterprises with cloud-based solutions to create & maintain killer web experiences with the open-source social publishing system Drupal. ► The Acquia Network is the ultimate Drupal management suite. Try it free for 30 days: bit.ly/yxUbKO ► Acquia Cloud gives you the simplicity you want with the reliability & scalability you demand: bit.ly/xVDm7D ► Drupal Gardens is a SaaS platform that makes building Drupal websites easier than ever before: bit.ly/A4YSyd

In an important time for truth in journalism — and in a world where readers find content in distributed ways — Chartbeat enables media organizations to understand and harness genuine audience engagement. As the analytics partner for more than 50,000 leading media sites around the globe, Chartbeat tracks what people are reading on a second-by-second, pixel-by-pixel basis on each site, article and page. Our content intelligence tools and quality metrics go beyond clicks and pageviews so you can understand reader engagement — the amount of time users spend actually reading content. This helps you value your best stories and ensure they thrive across platforms and devices.

Insurify is a comprehensive insurance comparison platform that allows users to instantly search, compare, and buy insurance online. Our goal is to transform the user experience for insurance shoppers, from quotes comparison to online bind. We're building a personalized experience, helping consumers make the right decision for their coverage, and saving them up to hundreds each year on their insurance premiums. Our team members and advisors are leaders from KAYAK and TripAdvisor and thought leaders from the insurance industry. Browse. Compare. Discover.

Karius is a life sciences company focused on generating genomic insights for infectious diseases with a non-invasive karius® test that helps clinicians make rapid treatment decisions. our laboratory is clia-certified and cap-accredited to perform high-complexity clinical laboratory testing. we provide unique genomic insights by detecting microbial cell-free dna (mcfdna) circulating in the bloodstream from pathogens causing an acute infection. proprietary technology efficiently extracts mcfdna directly from blood and depletes the strong human background signal and environmental contaminants. advanced machine learning algorithms allow analysis of complex genomic data in real-time. proprietary reference genome databases are constantly refined as more data becomes available.