Top Tech Startups in California, US in 2027

Biograph is a healthcare technology company that provides a series of comprehensive in-person assessments to gain insight across multiple dimensions of longevity. Members receive head-to-toe testing to provide a complete picture of their health. It continues through the year with ongoing engagement to help members meet their health and longevity goals. It's a longevity platform that aims to make significant progress in improving the lifespan and quality of human life as it delivers unparalleled service at their world-class facilities.

Epia Neuro is a neural technology company developing intent-driven systems designed to restore function and independence for people living with neurological conditions. Its platform integrates implantable neural interfaces, adaptive algorithms, and assistive devices to translate neural intent into real-world action. The company’s initial focus is stroke-related motor impairment, with expansion in cognitive decline and other neurological disorders, focusing on long-term solutions for the growing aging population.

Sparcle builds AI that enterprises can run inside their own walls. Bolt is a desktop workspace for Windows, Mac and Linux. One hotkey opens search, files, notes, a browser and 80+ utilities that run on your machine with no model call. When Bolt's AI runs, it masks secrets and personal data before anything leaves the device. Bolt is free for individuals and needs no account. Aeira is self-hosted enterprise search that checks each person's permissions before a document can be retrieved, so AI answers only use what that person may see. Enterprise deployments run on your infrastructure, with your own models and keys. Every consequential action is recorded in a signed audit trail that an auditor can verify offline. We are a small founding team in Sunnyvale, California, working on privacy, security and trust for AI at work. Founded in 2025. Download Bolt: sparcle.app/download