Top Software Startups in North America

Ewith.me is an AI-powered education, career, and productivity platform providing privacy-first tools for learning, writing, career development, exam preparation, and college discovery.

Healthcare in the U.S. is fundamentally broken. The system is so complex that 88% of U.S. adults do not have the health literacy necessary to navigate it without help. Solace cuts through the red tape of healthcare by pairing patients with expert advocates and giving them the tools to make better decisions—and get better outcomes. We're a Series B startup, founded in 2022 and backed by Inspired Capital, Craft Ventures, Torch Capital, Menlo Ventures, and Signalfire. Our fully remote U.S. team is lean, mission-driven, and growing quickly. Solace isn't a place to coast. We're here to redefine healthcare—and that demands urgency, precision, and heart. If you're looking to stretch yourself, sharpen your edge, and do the best work of your life alongside a team that cares deeply, you're in the right place. We’re intense, and we like it that way.

Today, 92% of low-income households can’t afford legal help, and meaningful reform is blocked by laws that prohibit non-lawyers from owning or operating law firms. Our mission is to change that. By equipping law firms with cutting-edge AI and world-class operations, we will push the industry 10 years forward, increasing the capacity for law firms to serve more clients so more households have access to justice. And we’re starting with plaintiff personal injury law firms. If we help 1-2 PI firms dominate in each state, we can raise the bar of competition and brute force massive change and unlock a legal system that works for everyone.

Early-stage startup.

Guile is a cybersecurity and AI engineering company building an autonomous penetration testing platform. We operate at the intersection of offensive security and agentic AI systems to give software teams continuous, red-team-level security validation.

Wise Agents is building the next generation of AI-powered digital employees for modern businesses. We help organizations automate repetitive and time-consuming workflows across operations, procurement, logistics, quoting, sales, and customer support. Our platform integrates with the tools companies already use—including CRMs, ERPs, email, spreadsheets, and messaging platforms—to enable teams to work faster, smarter, and more efficiently. Founded by a team of engineers, operators, and entrepreneurs, Wise Agents is focused on bringing practical AI to industries that have historically been underserved by emerging technologies. Our customers span manufacturing, distribution, logistics, and supply chain organizations across North America and Latin America, where our AI agents are already helping businesses reduce manual work, improve response times, and scale operations without increasing headcount. We're a fast-growing startup with significant commercial traction, a strong customer pipeline, and an ambitious vision: to build AI employees that become an essential part of every company's workforce. If you're excited about solving challenging problems, working directly with customers, and helping define the future of enterprise AI, we'd love to hear from you. We have raised over $1M USD till date.