Top Software Startups in 2026

EngagedMD is a fast-growing B2B software company that has developed the leading patient journey management solution for the fast-growing fertility sector. Nearly half of fertility patients in the US use our eLearn and eSign tools. Clinics use our software to reduce repetitive, manual tasks and streamline the patient journey, which helps them increase capacity and growth while improving the patient experience and reducing doctor and staff burnout. We are known for having a collaborative, friendly, high energy and fast-moving culture and a focused, start-up atmosphere.

Fullscript is a disruptive healthcare technology and service company. Our portfolio brings together the best nutritional supplement wholesale business with the premier online supplement dispensing platform. We provide innovative solutions for integrative practitioners and patients who seek a personalized experience and a holistic approach to healthcare. In the summer of 2018, Natural Partners, a national player in wholesale supplement distribution, merged with Fullscript, the creators of the first online supplement dispensing platform, to create Natural Partners Fullscript. Since then, NPFS has been the preferred partner of over 300+ professional supplement brands, EHRs such as Power2Practice and Jane, and major influencers in integrative health including Dr. Josh Axe and Dr. Aviva Romm.

Ornith Labs is a hybrid government/commercial research and development (R&D) team at Edgesource Corporation focused on national security and public safety missions in the world of "Counter UAS" (cUAS). Our solutions are used by companies and governments worldwide to keep civilian populations safe from the threat of weaponized commercial-grade drones. We recognize that the future of autonomous uniquity will create tremendous opportunity, but also unprecedented dangers. Our work seeks to mitigate those dangers by proactively anticipating and defeating emerging threats. You can read more about us here: dronelife.com/2022/12/14/counter-uas-technology-for-the-private-sector-edgeso…

As passionate scientists and engineers, we are well aware of the plethora of critical problems in the world that cannot be solved because humanity simply does not have enough computing power. To address this, Vorticity is developing a radically new silicon chip architecture and system to dramatically accelerate scientific computing problems. Vorticity’s mission is to expand human ingenuity. To do that we are building a team of exceptional people to work together on big problems. Join us!

Confido (YC S21) automates the expensive work of retrieving and analyzing CPG accounting data so that fast-growing CPG brands can track and optimize their spend. In 2024, it shouldn’t take 100+ hours of human labor for Mr. Beast’s Feastables (one of our customers) to determine how many millions were spent on buy-one-get-one deals last quarter; and whether or not that money was well spent. To solve these problems, we’ve built an all-in-one solution that deeply integrates with ERPs and other accounting systems, scrapes financial data from retailers and distributors, and leverages modern AI to analyze financial documents. Today, we work with 50+ fast-growing brands, processing $1b+ in revenue. We have raised $3.6M from leading investors. Our team has deep industry experience from Anheuser-Busch and SimpleMills, and engineering experience from Google, Square, HubSpot, and ThoughtSpot.

JUST A VERY INTELLIGENT SYSTEM or JAVIS is a works platform that enables users to get their work done through simple conversations over interfaces like WhatsApp From enabling teams to analyse company data & access trusted AI driven insights on-the-go, to collecting orders from retailers & distributors - businesses use JAVIS in a variety of ways Launched in 2018, Javis is a fast-growing AI platform for enterprises and is relied upon by thousands of users to deliver superior business performance every day. We currently have two offices in Mumbai & Gurgaon We are committed to foster a diverse and inclusive workplace in Javis. We strongly believe that when people of different backgrounds, experiences and perspectives come together, we create a pleasant and supportive workplace that leads to better products for our clients Come do the best work of your life here at Javis and play your part in changing the way people work & learn

Conviva helps streaming businesses act within seconds of observation to grow their business ahead of the competition. Conviva’s leading global streaming analytics platform provides comprehensive, continuous, census-level measurement through real-time, server side sessionization at scale. Using just a single sensor and a single pipeline, its 60+ patent platform enables marketers, advertisers, tech ops, engineering and customer care teams to acquire, engage, monetize and retain their audiences. Conviva is dedicated to supporting brands like DAZN, Disney+, Hulu, Paramount+, Peacock, Sky, Sling TV, TED and WarnerMedia as they unlock the incredible opportunity in streaming media. Today the Conviva platform processes nearly 3 trillion streaming data events daily, supporting more than 500 million unique viewers watching 200 billion streams per year across 4 billion applications streaming on devices. To learn more, visit conviva.com. Conviva is headquartered in Silicon Valley, with offices in New York, London, Madrid, Bengaluru, Beijing and Singapore. Conviva is founded by professors from Carnegie Mellon and U.C. Berkeley and backed by NEA, Foundation Capital, and Time Warner Investments. To learn more, visit conviva.com.

Pixability is a video advertising software company that uses data science to optimize large, complex campaigns across YouTube, Facebook, Instagram, and Connected TV. The company’s industry-leading optimization and insights solutions are independently verified by the YouTube Measurement Program, the Facebook Marketing Partner Program, Oracle’s Data Cloud’s Moat Measurement, and other third parties. Pixability’s suite of solutions are used by the top media agencies and brands including Dentsu-Aegis, Havas, Interpublic Group, Omnicom, Publicis, and WPP, as well as Swatch, Ford, KIND, L’Oréal, and Puma. For more information about Pixability’s video advertising platform, please visit pixability.com.

We are leading Cloud based digital signage management platform. Ranked #1 on G2 as highest rated Digital Signage platform with over 700 reviews. Visit our website optisigns.com and watch 1 min overview video

Resonate Pulse is a SAAS platform that enables our enterprise clients to monitor and action customer feedback real-time, where it happens, when it happens. Both in the front-line and the strategy teams we help re-shape the business. We make sure to put the end-customer front and centre, and help create that differentiatior every business needs.