Top Diagnostics Startups in 2026

The human microbiome is the next frontier of precision medicine. Just like our genes, our microbiome is unique and can help predict our health in many ways, from our disease risk to how the drugs we take effect us. Most importantly, unlike our genes, it's dynamic - so can be harnessed for better health. There's just one problem - that same dynamism makes it extremely challenging to study, and that slows progress. Microbiome researchers need more data to turn potential into reality. That's why we're creating novel tools to track, analyze, and store daily microbiome profiles of clinical trial participants, providing vastly more data than is possible with current tools, all for a fraction of the cost. This gives investigators far deeper insight into how the microbiome influences and is influenced by clinical interventions. The outcome? Microbiome-based prescriptions and solutions that are personalized to meet patient needs.

We are developing and selling innovative sample prep systems and applications that improve the enrichment of rare biomarkers that are used in the diagnosis and management of cancer patients.

TOBY is a health tech company that offers early cancer detection with noninvasive, AI-powered tests.

FluxErgy is dedicated to creating efficient point-of-care diagnostics, by making laboratory technology more accessible to healthcare providers. Leveraging our engineering expertise, our platforms will allow diagnostic developers to bring their ideas to life.

Radiology is the second most used healthcare service, used by over 51% of the workforce annually. Despite the critical role of radiology in healthcare, the process for undergoing a medical imaging exam has remained unchanged for decades. OneImaging is solving this with a concierge approach and a premium-quality radiology network of over 4,000 vetted providers across 48 states, which also reduces imaging costs by 60-80%. Our solution helps patients and families access essential radiology services at fair prices and without surprise bills, all while delivering immediate savings and ROI for employers and payers on every exam.

Spartan is bringing complete sample-to-result DNA testing systems to medicine. Spartan’s technology fully integrates DNA collection, extraction and analysis, with an intuitive interface that is easy to operate. For the first time, healthcare providers and their patients can get DNA results on demand.

Informuta is an infectious disease intelligence company that forecasts drug resistance trajectories to guide antibiotic selection with precision and quantify treatment-emergent resistance risk for the first time. Informuta uses proprietary AI and novel predictive genomic biomarkers to give clinicians the confidence to choose therapies that won’t fail their most vulnerable patients - transforming antibiotic prescribing from reactive to predictive and empowering smarter, future-proofed decisions.