Top Artificial Intelligence Startups in San Francisco, CA

Create lets you turn English into full stack apps. It's an AI "text to app" builder for entrepreneurs. Our mission is to give everyone the power of software creation. Our ambitious first step is to power a new generation of entrepreneurs as their AI product engineer. We’re hiring for the early team (first 10) who want to create an iconic product and shape our culture. Our team is small and talent-dense. We’ve built products people love and look for people who care about building insanely great products. Our investors include Bessemer, Uncork and the founders of Shopify, Zapier, Turing, Docsend, Front, Intercom, Shippo, and more.

Post-human ideas that once belonged to science fiction are becoming material reality, embedded into technical systems through AI, robotics, biotechnology and new forms of computation. Yaya Labs is a technology studio born from science fiction. It started with a humanoid robot: a vector for experimentation that led to our first personality protocol, an embodied AI persona trained on ethics, memory, aesthetics and emotional grounding, and road-tested at cultural events around the world. From there, we began exploring what happens when human wetware, artificial intelligence and machine systems begin to converge. Today, Yaya Labs operates at the conceptual edge of human-machine relations, developing new interfaces between biology, technology and culture. We explore AI personality protocols, embodied intelligence, brain-computer interfaces and systems that challenge the boundaries of individual agency. The next phase of AI isn't simply about making machines more intelligent. It's about what happens when intelligence becomes embodied, networked and alive.

FleetWorks automates the 2B phone calls and emails that the freight industry makes every year. We use voice synthesis, generative AI, and integrations with logistics systems to solve the largest cost in this industry - people. We are a fast-growing startup in the logistics space led by a founding team from companies like Airbnb and Uber Freight. We are a YC backed company. For more information about us, visit ycombinator.com/companies/fleetworks

Therapists hold the world together. They also run businesses, file insurance claims, write letters, fill forms, supervise new grads and do hours of paperwork every night. Practice management software has existed for decades. It records what therapists do. It can't actually do any of it. Klara is the AI at the heart of Klarify. She handles the work that comes after the session: clinical notes, treatment plans, clinical letters, insurance claims, between-session resources, supervision prep and finding new clients. More than 11,000 therapists use Klarify today. Privacy comes first: Klara never trains on therapists' notes or client data. Our mission is to empower therapists, not replace them, so they can focus on the one thing only a human can do: be present with their client. Klarify is backed by Y Combinator (Spring 2026) and has raised $1.7M. Moody (CEO) is a second-time founder who co-founded Circleback.ai and hosts the Future of Therapy Podcast. Bergie (CTO) built LLM infrastructure at Workday.

Construction is one of the largest industries in the world, but it is also one of the least technologically innovative spaces. Conducting fast and accurate cost estimates is a massive pain point because of the tedious nature of takeoffs (measuring & counting materials needed from the drawings). Bobyard automates the construction takeoff process with CV and NLP models to make cost estimates 10x faster while eliminating mistakes. We are a lean startup backed by some of the best VCs in the world: 8VC, Primary, and Pear. Almost all of the work lies ahead of us. We are excited to create next-gen software for the built world!

Increase revenue and speed-to-market with our industry-defining AI design software. Our software enables fashion brands and retailers to understand consumer demand and create unique designs that are in high demand with high purchase likelihood, in minutes, not months. We bring the best industry-leading AI analytics and generative AI capabilities to fashion product development. Join some of the top 10 global fashion brands using our software to turbocharge the design and merchandising processes.

Uplane (YC F25) replaces marketing agencies with AI. We generate hundreds of ads with matching landing pages and steer the ad spend across channels like Meta, Google, LinkedIn and others. By connecting to CRM and ERP data, Uplane learns what drives profits and continuously improves campaigns. Companies waste billions on bad ads, mismatched landing pages, and poor budget allocation. Uplane fixes this by replacing a patchwork of agencies, spreadsheets, and siloed tools with one self-improving system. The result: Higher ROAS for enterprises and effortless, expert-level marketing for SMBs.

Traba is building a world where the global supply chain operates at peak efficiency. We connect industrial businesses with reliable workers to fill open shifts and empower both businesses and workers to reach their full productivity and potential.