Top B2B Startups in 2026

DATAMARK Inc., a provider of omni-channel contact centers and business process outsourcing (BPO) services since 1989, employs more than 4,500 people at our facilities in the United States, Mexico and India. DATAMARK, Inc. is a leading global Contact Center and Business Process Outsourcing (BPO) company headquartered in El Paso, Texas. We serve Fortune 500 companies, large enterprises and government agencies from delivery centers in the U.S., Mexico and India Our Fortune 500 and enterprise clients trust us to be an extension of their brand. DATAMARK contact center agents are proud to represent many of the most well-known companies and brands across the globe. We deliver unparalleled customer service in our omnichannel contact centers, ranging from SMS text to video chat and everything in between that your customers expect the world’s leading brands to have equipped. Our long-term client partnerships include customer care for leading international companies across a wide array of industries, including BFSI, interpretation & translation services, transportation, healthcare, and consumer electronics. Learn how DATAMARK combines outstanding omnichannel customer care, brand promotion, and continuous process improvement to deliver an unparalleled customer experience. Visit us at DATAMARK.net.

Modernizing Government. Maximizing Impact. GAMA-1 Technologies is a mission-driven, Small Disadvantaged Business empowering federal agencies to deliver smarter services through secure cloud modernization, AI-driven automation, and zero trust cybersecurity compliance. We specialize in enabling decision support mission critical data to benefit humanity—leveraging innovation to streamline government and accelerate outcomes that matter. With deep roots in environmental observation infrastructure and data modernization, we help agencies like NOAA, NASA, and others transform legacy systems, unify mission data, and embrace digital-first operations. Our solutions are engineered for public good—driving efficiency, reducing costs, and amplifying mission success. Powering Federal Efficiency Through Innovation, GAMA-1 delivers: • AI-Driven Analytics & Automation – Eliminating duplication of efforts and optimizing workflows. • Cloud & Infrastructure Modernization – Migrating to scalable, secure, and mission-ready environments. • Enterprise Data Management & Governance – Breaking down silos for smarter decision-making. • Adaptive Cybersecurity & Compliance – Safeguarding critical systems, protecting data integrity, while meeting evolving federal mandates. • Digital Transformation & Mission Enablement – Accelerating delivery with DevSecOps, low-code, and re-engineering. As an AWS Advanced Tier Partner, MS Partner, Scaled Agile Silver Partner, and Weather-Ready Nation Ambassador—with ISO 9001, 20000, 27001 certifications—we align technical precision with mission impact.

National Solar Technologies (NST), a Division of National Manufacturing & Distribution, Inc., has been going strong in the field of engineering and building solar power systems and solar lighting systems since 1997. Their systems are built to last and engineered for reliability in the most extreme types of climates and locations around the world. Their attention to detail when developing their systems allows for high reliability in austere and remote environments. National Solar Technologies has received awards from both the US Military and independent national award contests for systems that are operating in the USA and overseas. NST manufactures & supplies energy saving solutions to military/government customers as well as industrial/commercial customers throughout the world.

Language shouldn’t determine the quality of your care, but for 30 million patients in the U.S., it still does. Lexi is an early stage Harvard–backed startup building AI-native, real-time medical interpretation so clinicians and patients can communicate clearly across languages. Every day, clinicians lose precious time and patients face preventable risks because they can’t speak the same language, while traditional interpretation services remain slow, costly, and inconsistent in quality. For patients with limited English proficiency, this shapes every encounter with the health system. We’re building the real-time multilingual communication layer for healthcare to deliver instant, medically accurate, voice-to-voice interpretation using advanced speech processing and multilingual AI. Lexi is optimized for clinical workflows and engineered with HIPAA-grade privacy to protect patient data. Join us in making healthcare truly accessible for all!

Software is for running engineering teams is clunky, isolated, and costly - leveraging AI tools on top of them is harder than it should be. We're building a brand new workspace, from the ground up and open-source, to make the development process as frictionless as possible. Inter-team messaging, email wrappers, Markdown notes, Github integration, developer task management, a LaTeX editor, we want it all! You can check out, and contribute to, our repo here: github.com/macro-inc/macro We're an NYC based company, at Series A1 stage, in-office 5 days a week and fully comprised of software engineers from the top-down. We offer competitive compensation, great benefits, and an office culture unlike any other startup you've seen. If you like Rust, if you "like" Typescript, if you like AWS Cloud Development, if you're into open-source development creating tools for other engineers, give us a call!