Top B2B Startups in 2026

Pathos develops an AI-enabled drug discovery platform to reduce the medication development process. Its self-learning platform utilizes big data, technology, and artificial intelligence to identify targets, validate them, and establish their clinical efficacy. It also helps drug developers to explore novel concepts, and advance breakthrough therapies. The company's OS platform is capable of managing the entire end-to-end process of designing and developing novel therapeutics.

Orion Systems Integrators is an Information Technology resource dedicated to delivering IT services and solutions.

SELECCIÓN Consulting stands at the forefront of SAP consulting, embodying innovation in every facet of our services. Our firm is dedicated to becoming your trusted partner for all your digital needs, offering a comprehensive suite of solutions tailored to meet your unique requirements. With a focus on advisory, projects, managed services, and staff augmentation, SELECCIÓN Consulting delivers unparalleled expertise and support across the entire spectrum of SAP services. Our team of seasoned professionals is committed to providing strategic guidance and hands-on assistance to help you navigate the complexities of digital transformation seamlessly. At SELECCIÓN Consulting, we are proud to introduce RISE, a groundbreaking initiative designed to revolutionize your digital experience. With RISE, we bring unparalleled speed, agility, and cost efficiency to your digital endeavors, ensuring maximum returns on your investments. Whether you're looking to streamline processes, enhance productivity, or drive growth, RISE empowers you to achieve your goals with confidence and ease. As a trusted reseller and certified partner, SELECCIÓN Consulting boasts expertise across a diverse range of products and platforms. From S/4 HANA Public and Private Cloud to Google Cloud Platform migrations and management, UiPath automation, Pillir low-code/no-code assets, and ServiceNow integration, we offer comprehensive solutions to address your most pressing business challenges. Our commitment to excellence extends beyond mere solutions – it is embedded in every interaction, every recommendation, and every outcome we deliver. At SELECCIÓN Consulting, we are not just a service provider; we are your dedicated partner, invested in your success and committed to helping you unlock the full potential of your digital initiatives. Choose SELECCIÓN Consulting as your partner for SAP consulting, and embark on a transformative journey towards digital excellence. Experience the difference of working with a team that prioritizes innovation, collaboration, and results, and discover the true power of partnership in driving your business forward.

Since 1966, GPI has designed, managed and supported their clients on a wide array of projects. They’re employee-owned, known for their technical knowledge and commitment to getting each job done well. Their widely-recognized quality of service rises from the talent and energy of their exceptional team. The work ethic and dedication of the men and women at GPI allow us to deliver consistent, quality service to government agencies, municipalities, architects, commercial developers, and property owners. Their values as a firm and their commitment to their core strategic objectives including Employee Satisfaction, Quality Product, and Client Satisfaction have contributed to their continued growth and the confidence of their longstanding client relationships.

Cennox is a Global ATM Services & Fit Out Solutions business. Cennox provide a wealth of sector specific services and project capabilities designed to help our banking clients increase transaction levels and reduce costs. With offices and representation in 13 Countries and customers in over 100, Cennox is a leading brand for ATM Related Services.

Tek Global Data Analytics services help build intelligent solutions for data-driven businesses. Tek Global offers Data Management, Business Intelligence, Data Visualization and Advanced Analytics Solutions with 'Intelligence-First' Principle at the core and advocates true 'Data Democracy'.

Valcourt Building Services is a premier provider for waterproofing, restoration, and window cleaning services. Valcourt works on commercial office buildings, high-rise residential buildings, parking garages, hospitality, and healthcare buildings. Services include concrete repair, caulking, pressure washing, façade restoration, leak repair, bird proofing, epoxy injections, fall-protection systems, and rooftop anchors. The company was founded in 1986 and has grown from a small window cleaning company serving the Washington, DC area into one of the largest exterior maintenance companies in the country. From our corporate offices we proudly serve clients in Connecticut, New Jersey, Pennsylvania, Maryland, Virginia, Georgia, Florida, and Texas.

Automated Tire (ATI) is a trailblazing Series-A startup dedicated to transforming the tire-changing and wheel-balancing industry through innovative robotic technology. Founded by a team of seasoned entrepreneurs with deep expertise in the tire and automotive sectors, ATI is positioned to redefine the future of automotive service. Our Mission: ATI is overhauling the century-old tire-changing process. Frustrated by the inefficiencies and outdated methods prevalent in the industry, our founders set out to create a solution that integrates cutting-edge robotics to streamline tire service. Our goal is to deliver a faster, safer, and more efficient experience for customers, tire shops, and dealerships alike. What Sets Us Apart: Innovative Robotic Technology: Leveraging state-of-the-art robotics, ATI enhances the speed and accuracy of tire-changing and balancing, setting new standards in the industry. Experienced Team: Our team includes top talent from the Boston robotics community, with a proven track record in scaling successful startups and pioneering technological advancements. Strategic Backing: Supported by leading investors from the automotive and tire sectors, ATI is well-positioned for rapid growth and long-term success.