Top Tech Startups in Missouri, US in 2026

Today, there's more data and users outside the enterprise than inside, causing the network perimeter as we know it to dissolve. We realized a new perimeter was needed, one that is built in the cloud and follows and protects data wherever it goes, so we started Netskope to redefine Cloud, Network and Data Security. Since 2012, we have built the market-leading cloud security company and an award-winning culture powered by hundreds of employees spread across offices in Santa Clara, St. Louis, Bangalore, London, Melbourne, and Tokyo. Our core values are openness, honesty, and transparency, and we purposely developed our open desk layouts and large meeting spaces to support and promote partnerships, collaboration, and teamwork. From catered lunches and office celebrations to employee recognition events (pre and hopefully post-Covid) and social professional groups such as the Awesome Women of Netskope (AWON), we strive to keep work fun, supportive and interactive. Visit us at Netskope Careers. Follow us on LinkedIn and Twitter @Netskope for more updates.

Chowbus is a food ordering platform which curates featured dishes from selected ethnic restaurants daily and delivers them fresh and hot to your home or office affordably with the tap of your cell phone. We provide dish-centric mobile ordering experience for consumers to easily explore and order authentic ethnic food and we empower local ethnic restaurants with the technology, tools, and marketing to grow their business.

Better data leads to more performant models. Performant models lead to faster deployment. We help deliver value from AI investments faster with better data by providing an end-to-end solution to manage the entire ML lifecycle.

PermitFlow is redefining how America builds. We’re an applied AI company serving the nation’s builders, tackling one of the largest information challenges in the economy: understanding what can be built, where, and how. Our AI agent workforce helps the fastest-growing construction companies navigate everything from permitting and licensing to inspections and project closeouts – accelerating housing, clean-energy, and infrastructure development across the country. Despite being a $1.6T industry, construction still suffers from massive delays, wasted capital, and lost opportunity. PermitFlow has already delivered unprecedented speed, accuracy, and visibility to over $20B in development, helping contractors reduce compliance time, de-risk projects, and scale with confidence. America is entering a CAPEX super-cycle, from data centers and factories to housing and renewables, and joining PermitFlow is building the AI at the heart of every construction project powering the next wave of re-industrialization. We’ve raised over $90M, most recently completing our Series B, from top-tier investors including Accel, Kleiner Perkins, Initialized, Y Combinator, Felicis, and Altos Ventures, with backing from leaders at OpenAI, Google, Procore, ServiceTitan, Zillow, PlanGrid, and Uber.

Our mission is to accelerate progress toward a smaller, fairer, safer criminal justice system—and to do so at-scale. Recidiviz is a tech startup through and through: we take the speed and problem solving of the tech world and apply it to big public policy challenges where there is huge opportunity for impact. Using modern data infrastructure and thoughtful product design, we’ve been able to safely and permanently reduce incarceration and improve outcomes. We work side-by-side with justice-impacted communities, ecosystem partners, and leaders of the criminal justice system to build a better path forward. In addition to the revenue we earn from states, some of the most respected philanthropists and foundations—including Arnold Ventures, the Chan Zuckerberg Initiative, and the Mozilla Foundation—support our work.

Varsity Tutors is a live learning platform that connects students and professionals with personalized instruction to achieve any goal. To date, students have accessed more than three million hours of live instruction on the platform. Experts are available to meet in person or through the company’s award-winning online and mobile platforms, which account for the majority of all sessions.

We built a nationwide legal services platform that helps law firms and pro se parties gain access to more efficient, transparent, and accessible legal services that are not traditionally available. Our main services are Service of Process and E-Filing .We currently serve over 2,000 law firms throughout the US, as well as countless pro se parties.

Pomelo Care is the national leader in evidence-based healthcare for women and children. We deliver personalized, high-quality clinical interventions from reproductive care and pregnancy, infant care and pediatrics, to hormonal health through perimenopause and menopause, with long-term preventive care and condition management. Our model delivers 24/7 multispecialty care to address the medical, behavioral, and social factors that most significantly impact outcomes for women and children. We partner with payers, employers, and providers to expand access to quality healthcare across the system. To search career opportunities or to learn more, head to pomelocare.com.

Archesys provides a wide range of technical services and has been doing so for over 20 years, making a significant impact in the areas of organization, culture, and technology in both the private and public sectors. From digital modernization to process management, our team is the go-to resource for various government agencies looking to improve or overhaul their operations.

Machinio.com is one of the world’s largest platforms connecting buyers and sellers of inventory and related services across multiple industries. Founded in 2013 and acquired in 2018, Machinio now serves over 4,000 paying clients globally and continues to expand its reach and impact. Thousands of dealers and suppliers rely on the platform to market and sell their equipment, connecting them with millions of prospective buyers each year. Machinio is widely recognized for leveraging technology to simplify and modernize the buying and selling process. By introducing innovative tools and improving marketplace efficiency, the company has helped both buyers and sellers save significant time while facilitating high-value transactions worldwide. Machinio System is Machinio’s all-in-one software solution built specifically for dealers and service providers. Launched in 2018, it combines modern, fully customizable, SEO-optimized websites with a fully integrated CRM platform for dealers. This unified solution enables businesses to manage their entire workflow in one place — including inventory, lead management, quoting, invoicing, contact databases, email marketing campaigns, and more. With continuous feature development and a strong product roadmap, Machinio System empowers dealers and service providers to maintain a professional online presence, leverage intelligent sales and marketing tools, and consistently generate and nurture business opportunities. Machinio has been featured in leading media outlets including Forbes, Business Insider, Inc., EquipmentWorld, Agriculture.com, and others.