Top Biotechnology Startups in 2027

Intelligent Digital Drug Discovery and Development (ID4) platform, which provides - Crystal Structure Prediction - Computation of Relative Free energies - Solubility predictions - Prediction of Nucleation Conditions for Crystal Structures for biotechnology and pharmaceutical clients

Curi Bio is innovating at the intersection of human stem cells, tissue-specific biosystems, and AI/ML-enabled data analytics. Curi helps scientists and drug developers create highly mature, predictive iPSC-derived cell models, innovative biosystem designs that enable high-throughput clinically-relevant readouts, and phenotypic screening using deep learning techniques for cell-based assay insights.

Our CapsidMap™ platform uses AI to systematically and rapidly optimize AAV capsids, overcoming the limitations of naturally occurring virus capsids by improving targeting ability, payload size, immune evasion and manufacturability. By building a massive and detailed map of synthetic AAV capsid sequence space, we can quickly navigate the landscape to find enhanced gene therapy vectors with transformative potential.

Deep Genomics is using artificial intelligence to build a new universe of life-saving genetic therapies. The future of medicine will rely on artificial intelligence, because biology is too complex for humans to understand. At Deep Genomics, our geneticists, molecular biologists and chemists develop new ways of detecting and treating disease using our biologically accurate artificial intelligence technology

Platform that can be customized for a variety of research purposes - clinical document abstraction, Mass Spec repository, longitudinal study data management

Lifebit is a leading innovator in bioinformatics software solutions and AI. In 2021, the London, UK based company closed its Series B funding round of US$60M led by Tiger Global, to fuel ongoing product innovations and global market expansion. Lifebit is pushing forward the frontiers of health and knowledge by democratising access to, and powering analyses of, omics big data. We are the pioneers revolutionising bioinformatics and biomedical data analysis. The company’s flagship product, Lifebit CloudOS, is fast becoming the industry’s standard for unified and secure research over distributed big data. On top of its core foundation, the platform provides integration to open-source analysis and visualisation tools, as well as a marketplace of proprietary ones, a powerful data and cohort browser, and advanced AI functionality that together are powering discoveries in drug discovery and vaccine development. Top tier pharmaceutical organisations, global research institutes, and bioinformatics companies the world over are deploying Lifebit CloudOS. In April 2020 we closed our Series A funding round with tremendous support from new and previous investors. Based in London, UK, Lifebit is a diverse team spanning Europe and North America, with each person empowered and involved in every aspect of the business.

The company leverages machine learning, automation, and peptide synthesis to build platforms for science at scale. With its foundations in engineering disciplines, the company’s platforms vertically integrate proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance basic research, target validation, and clinical trials.

Excelra's data and analytics solutions empower innovation in life sciences across the value chain from discovery to market. The Excelra Edge comes from a seamless amalgamation of proprietary curated data assets, deep domain expertise and data science. The company's multifaceted teams harmonize and analyze large volumes of disparate unstructured data using cutting-edge technologies. We galvanize data-driven decisions to unlock operational efficiencies to accelerate drug discovery and development. Over the past 18 years, Excelra has been the preferred data and analytics partner to over 90 global clients including 15 of the top 20 large Pharma companies.

Our mission is to harness advanced technologies to increase our understanding of the biology that underlies lifespan, and to seek interventions that enable people to lead longer and healthier lives. We bring together scientists and technologists, thinkers and tinkerers, to explore the fundamental biology of aging. At Calico, you'll work closely with scientists to help ask big scientific questions, and invent software to help answer them. We're part of the Alphabet family, which includes Google, Verily, Waymo, and other companies.

Manifold is a leading research cloud built for life sciences. Biomedical research is now about data of increasing scale, modality, velocity, and complexity. It is also inherently collaborative. The old tools aren’t working. Manifold gives researchers a single place to collect, harmonize, and analyze life sciences data, without having to set up compute infrastructure, do complex data integrations and prep, or hire a large software team.