Puzzle Medical Devices careers

An estimated 26 million patients suffer from heart failure worldwide, resulting in a global healthcare spending of $108B. While great improvements in chronic heart failure therapy have been achieved in the last couple of decades, mortality and readmission rates have seen a limited impact. Patients with advanced heart failure − refractory to medical therapy − are often at increased risk for conventional surgical left ventricular assist device implantation. Even with optimal patient care, cumulating to yearly spending of $28B in the United States, these patients have a 2-year survival rate of 50% and limited quality of life.

Puzzle Medical Devices Inc. is a Canadian company with the focus of improving patient quality of life and reducing the global economic burden related to heart failure. ModulHeart features a proprietary modular assembly allowing sequential percutaneous implantation of the pump components, which are then assembled using a transcatheter technique. The device is implanted in the descending aorta and is designed to augment native blood flow and end-organ perfusion in order to stabilize patients with advanced stage heart failure, halt disease progression and avoid acute decompensations. Its minimal trauma to the blood components, allows for long-term, safe and efficient heart support without open-heart surgery. To date, Puzzle Medical has successfully completed acute in-vivo preclinical implantations with tremendous success.