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Therapeutic hypothermia, or total body cooling, is a cost-effective treatment method used to improve survival rates and outcomes following cardiac arrest, myocardial infarction, stroke, subarachnoid hemorrhage, traumatic head injury, spinal cord injury, neonatal encephalopathy, heatstroke, cerebral edema, subarachnoid hemorrhage, and ARDS. The field of therapeutic hypothermia is evolving, with better understanding of the molecular effects of hypothermia and the development of hypothermia induction equipment based on different physiological principles.
The ideal hypothermia induction device should meet the following requirements: provide fast rate of cooling; allow body temperature within a narrow range; non-invasive, compact, easy-to-use, and transportable; have a low side effect profile; provide easy access to the patient; allow for controlled rewarming.
No commercially available device meets all of these criteria. Because of the lack of accepted standards in cooling methods and the inability of a select induction device to meet all ideal requirements listed above, the acceptance of therapeutic hypothermia by the medical community is not as widespread as it could be.
Conversely, a simple, compact, and easy-to-use hypothermia induction device with a favorable side effect profile can become a standard in providing hypothermia therapy. In collaboration with the Department of Engineering at the University of Kansas, we have designed, built and tested a prototype device based on a new physiologic principle of body cooling by administering Hyper-Cold Air™ through a mechanical ventilator using normoventilation or Compensated Hyperventilation™.
We believe our method of hypothermia induction will address the shortcomings of existing hypothermia devices and potentially replace other methods and equipment currently in use. The new device will bring uniformity to the hypothermia equipment industry, expand the use of therapeutic hypothermia in hosp
The ideal hypothermia induction device should meet the following requirements: provide fast rate of cooling; allow body temperature within a narrow range; non-invasive, compact, easy-to-use, and transportable; have a low side effect profile; provide easy access to the patient; allow for controlled rewarming.
No commercially available device meets all of these criteria. Because of the lack of accepted standards in cooling methods and the inability of a select induction device to meet all ideal requirements listed above, the acceptance of therapeutic hypothermia by the medical community is not as widespread as it could be.
Conversely, a simple, compact, and easy-to-use hypothermia induction device with a favorable side effect profile can become a standard in providing hypothermia therapy. In collaboration with the Department of Engineering at the University of Kansas, we have designed, built and tested a prototype device based on a new physiologic principle of body cooling by administering Hyper-Cold Air™ through a mechanical ventilator using normoventilation or Compensated Hyperventilation™.
We believe our method of hypothermia induction will address the shortcomings of existing hypothermia devices and potentially replace other methods and equipment currently in use. The new device will bring uniformity to the hypothermia equipment industry, expand the use of therapeutic hypothermia in hosp
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Sergei Shushunov, MD
Founder TTM Inc, MD, Critical care pediatrician,
inventor, entrepreneur
Valuation
$0
Funded over
1 round
Latest round
Seed (Jun 2014)
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