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Kinovi is developing novel drug binding kinetics at scale for accelerated drug discovery1-10 Employees
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Kinovi is developing novel drug binding kinetics at scale for accelerated drug discovery
Kinovi’s proprietary Conformational Dynamics Electrotransduction (CODE) allows monitoring of conformational changes that occur when an analyte and its target interact. These measures are based on a quantum tunneling phenomenon that generates an electromagnetic signal capable of being captured via a specially purposed field-effect transductor. Proprietary methods allow for the stabilization of the biomolecule into nanodisks with little to no modification compared to their native structure. This allows for the target-analyte interaction to be captured in a time-resolved manner, with enough sensitivity to classify the interaction (allosteric/orthosteric), and even with the possibility of performing biased agonism studies. Our solution is protected by a comprehensive IP portfolio covering critical aspects of the process as well as proprietary methods kept as trade secrets.
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