Jobs at Flagship Pioneering

• Define Iris Chat’s product vision, target users, most valuable use cases, differentiation, and roadmap. Translate long-term ambition into clear priorities, making disciplined decisions about what to build, sequence, and stop.
• Own the customer journey from onboarding and the first useful conversation through ongoing use ...

• Across a range of disease/therapeutic areas, build a deep understanding of addressable markets, industry landscape, customer (health care practitioner, payor, and patient) needs, and forecast future states and opportunities for growth in sectors of interest
• Carry out market sizing, competitive analysis using epidemiology, clinical, and commercial data...

• Own and operate Flagship's portfolio bioinformatics platform stack — including CodeOcean, Sequera (Nextflow Tower), Tamarind.bio, and adjacent tools — serving as the primary administrator, configurator, and first point of escalation for platform-level issues.
• Build and maintain a library of reusable, production-quality pipeline templates and starter dep...

• Lead, mentor, and grow , including external contractors and consultants; set a high technical bar and foster a culture of rigor, collaboration, and continuous improvement.
• Serve as a player-coach — providing direct technical contributions while managing team capacity, priorities, and professional development.

• Program Leadership: Lead development, implementation, control, and reporting of several AI/ML or computational projects within assigned ventures in line with broader strategic plans of PI and Flagship, budgets, and timelines.
• Technical Ownership: Take a specialized technical role on project teams to oversee method deve...

• Own and continuously evolve a multi-year research roadmap spanning predictive modeling, causal inference, and longitudinal analysis, informed by scientific, clinical, product, and market evidence.
• Translate the research roadmap into practical milestones, decision gates, and resource requirements.

• Own and continuously evolve a multi-year research roadmap spanning predictive modeling, causal inference, and longitudinal analysis, informed by scientific, clinical, product, and market evidence.
• Translate the research roadmap into practical milestones, decision gates, and resource requirements.

• Administer and optimize core research systems including ELN, LIMS, data management platforms, and other scientific tools including Benchling, CDD Vault, Quilt, AWS, Code Ocean, and Seqera, ensuring reliability, performance, and user satisfaction.
• Collaborate with stakeholders to gather, document, and translate requirements for R&D appli...

• Configure, tune, and iterate on autopilot firmware for fixed-wing airframes, including PID tuning, failsafe logic, auto modes, and mission scripting using ArduPlane;
• Read, modify, and debug ArduPilot source code (C++) to extend autopilot capabilities, implement custom behaviors, and resolve vehicle-level anomalies;

• Develop and execute a comprehensive business development strategy aligned with the company's scientific, clinical, and corporate objectives
• Identify, evaluate, and cultivate relationships with potential pharmaceutical, biotechnology, academic, and other strategic partners

• Serve as the technical lead and subject matter expert on complex data engineering projects involving interdependent systems, legacy environments, and emerging cloud-first platforms.
• Lead the implementation of data infrastructure, platforms, tools, and other data products.

About the role:

The VP, Business Development is a senior leader that will own the articulation and initial execution of the business development strategy for a subset of companies with the Flagship Pioneering ecosystem with the opportunity to negotiate and conduct transactions. The primary objec...

• Standard office environment in Cambridge with hybrid flexibility options.
• Collaborative, interdisciplinary teams engaged in high-impact innovation.

• Define Learning Targets & Model Advertising Performance – Identify the customer decision and business intervention to influence; construct training labels and measurement windows; assess data quality, bias, and leakage; and develop predictive models that forecast campaign and creative performance across channels, audiences, placements, and objectives.

• With drug development matrix teams, support the translation of overarching drug development strategy and vision into integrated, detailed project plans (scope, milestones, critical paths, dependencies, risks) across functions.
• Monitor progress versus plan; proactively identify issues and interdependencies, escalate to pr...

• Lead design, and execution of Flagship's visual communications across presentations, marketing collateral, digital assets, executive communications, events, and other internal and external materials, ensuring deliverables reflect the quality and innovation of the Flagship brand.
• Work with senior executives and cross-functional leaders to translate complex scientific, techn...

• Own the end-to-end monthly close process, ensuring GAAP compliance and timely, accurate reporting in alignment with each company's established close calendar.
• Manage core accounting functions including general ledger, accounts payable, vendor payments, payroll, equity administration, and treasury across all entities in scope.

• Lead the design, fabrication, and optimization of MEMS-based sensor components and microscale structures, from concept through manufacturable process.
• Develop and optimize cleanroom process flows including photolithography, thin-film deposition (PVD/CVD/ALD), dry and wet etching, and wafer bonding.

• Program Leadership: Lead development, implementation, control, and reporting of several AI/ML and computational projects within assigned ventures and PM programs across the preclinical, translational, and clinical continuum, in line with broader strategic plans of PI and Flagship.
• Technical Ownership: Own the build, scaling, benchmarking and maintenance of agentic systems th...

• Develop and optimize high-throughput automated protocols that translate biological workflows from the bench to integrated workcells.
• Partner with scientific teams to design automation solutions that balance biological fidelity, throughput, cost, reliability, and lead time.