Consumables NPI Engineer III

About the role:

We are seeking an outstanding Consumables NPI Engineer 3 to join the Manufacturing Systems Engineering (MSE) team at 10x Genomics. This is a key position for the commercialization of consumable products within the Global Operations Engineering team, and sustainment and technical stewardship of those products on-market. This multi-disciplinary position involves close collaboration with various groups including Microfluidics, Supply Chain Management, and New Product Development. You will play a key role in transferring new plastic components to volume manufacturing. This role partners with the Operations, NPI, Supplier Support, and R&D teams to improve robustness and efficiencies across multiple product lines.

The ideal candidate will have a proven track record in supporting complex plastic components used in on-market equipment for the life sciences or medical device industry. They should possess a broad understanding of the design and manufacturing of complex plastic systems and excel in solving complex problems.

What you will be doing:

1. Cross-Functional Collaboration

• Communicate NPI status, risks, and technical decisions to stakeholders across Operations, R&D, and Commercial teams.
• Support the Design for Manufacturability (DFM) feedback loop with R&D during transfer of new plastic components into manufacturing.

1. Supplier Support & Qualification

• Serve as the primary engineering point of contact for consumables suppliers during design, development and transfer of new products, driving qualification activities (e.g. IQ/OQ/PQ, first-article inspection, capability studies).
• Partner with Supply Chain Management to manage supplier relationships, including on-site engineering support as needed.
• Support supplier corrective actions and process changes to ensure yield, quality, and reliability targets are met ahead of production release.
• Provide as-needed support in life cycle management to ensure sustainment of on-market products.

1. Part Release & Change Control

• Own the part release process for new consumable components and assemblies, driving parts through ECOs/ECRs and change control to production status.
• Coordinate release readiness across engineering, quality, and supply chain gates to avoid downstream disruptions.
• Maintain accurate revision control and documentation throughout the release lifecycle.

1. BOM & Part Structure

• Build and maintain BOM and part structures in Arena PLM and Oracle ERP for new consumable products, ensuring accuracy of part numbers, revisions, and where-used relationships.
• Partner with Planning and Manufacturing to structure BOMs that reflect real production and supply chain flow.
• Troubleshoot and resolve BOM/part structure discrepancies that impact production, planning, or supply chain execution.

1. Manufacturing Documentation & WIN Development

• Author and maintain Work Instructions (WINs) for consumable manufacturing and inspection processes, ensuring clarity, accuracy, and compliance with quality requirements.
• Translate engineering specifications and process knowledge into effective, operator-ready work instructions.
• Support operator training and continuous improvement of documentation as processes evolve.

Minimum Requirements:

• Education: BS/MS in Mechanical, Manufacturing, Plastics, or Industrial Engineering.
• Experience: 6+ (BS) or 4+ (MS) years in manufacturing or NPI engineering, ideally within biotech, life sciences, or medical device industries.
• PLM/ERP: Demonstrated experience building BOM/part structures and managing part release using PLM (e.g. Arena) and ERP (e.g. Oracle) systems.
• Supplier Engineering: Experience qualifying and supporting suppliers (molding, machining, or assembly), including hands-on/on-site engineering support.
• Plastics: Direct experience with injection molding, LSR-thermoplastic assemblies, or precision plastics manufacturing - including direct experience in IOPQ planning and execution.
• Documentation: Experience authoring work instructions or manufacturing documentation in a quality-controlled environment.
• Change Control: Familiarity with ECO/ECR processes and engineering change management.
• Technical Foundation: Working understanding of 3D mechanical design, GD&T per ASME Y14.5, dimensional tolerancing, and process capability (Cpk/Ppk) analysis.
• Strong written and oral communication skills; ability to work cross-functionally across engineering, quality, and operations.