Vice President Information Technology

Soufflé Therapeutics | VP, IT | Job Description

Soufflé Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!

Position Summary:

As Soufflé Therapeutics scales, we need a technology strategy that keeps pace with growing complexity across regulatory, scientific, and business needs. As our first VP, IT, you'll build and own that strategy, getting systems and infrastructure phase-appropriate before scale becomes a bottleneck. This is a highly cross-functional, hands-on leadership role, with real ownership to build the function from the ground up.

Key Responsibilities

• Lead the evolution of IT strategy as Soufflé transitions from research to clinical development, while planning ahead for later-stage portfolio and company needs
• Own IT infrastructure, cross-functional AI agents, cybersecurity, data management, and compliance
• Lead stakeholders in triaging and prioritizing initiatives spanning AI/ML integration, new systems for science, regulatory, and G&A, and platforms that optimize drug discovery
• Build and own the change management process for new system adoption across stakeholder groups
• Operate as a highly integrative, cross-functional partner to the leadership team

What Success Looks Like

• In 3 months: You've aligned a growth game plan for the next 2–3 years, with clear plans in place for key initiatives spanning AI/ML, quality, legal, and HR
• In 6 months: Your system roll-outs are landing successfully
• In 12 months: You're already setting the strategy for the company's next stage of growth, staying ahead of what's around the corner

Qualifications — Required

• 15+ years of relevant IT leadership experience in a biotech/pharma, including 6+ years in a similar lead role
• Working knowledge of ICH and FDA regulations, and HIPAA compliance requirements
• Led AI implementations successfully including agents and enterprise wide Chatbots.
• Experience with AI/ML across a broad application space
• Experience in R&D organizations transitioning systems from research to development, ideally at high-growth companies
• A hands-on approach to change management – owning system roll-outs with stakeholders end-to-end rather than handing them off

Education

• Bachelor's degree required; advanced degree a plus

At Soufflé Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

This is an onsite position in Watertown, MA (US) with flexibility as needed for collaboration and external engagements.